Sentences with phrase «rna interference»

Thereafter, negotiated global settlement agreement by which UMass became a co-owner of Max Planck's competing patent applications on RNA interference.

Silencing Viral Genes Beeologics» solution, Remebee, utilizes a mechanism called RNA interference (RNAi, also known as gene silencing) a mechanism that inhibits or hinders gene expression.

Three Presentations, a double - sided worksheet on epigenetics and a fun class quiz which cover the following topics: Transcription Factors and the Oestrogen Receptor, DNA methylation and Histone Acetylation (epigenetics), RNA interference, as well as how these are implicated in cancers.

This applies to the design and manufacture of RNA, DNA, and viral products for research and laboratory use, including RNA interference, gene expression, and gene editing.

Utilizing a Nobel prize - winning technology known as RNA interference (RNAi), the Institute's new RNAi Center will be a catalyst for accelerating discovery toward new therapies against myriad diseases, and is one of a small, select group of dedicated RNAi facilities worldwide.

This complex plays a key role in the RNA interference (RNAi) pathway that silences gene expression.

These findings show, for the first time, that RNA interference could potentially serve as an important therapeutic alternative in the management of glaucoma risk factors.

Scientists are investigating the use of a process called RNA interference as a way of reducing elevated pressure in the eye that can cause glaucoma.

Using an RNA interference screen, Swanton and his colleagues identified a set of genes involved in the regulation of mitotic arrest and in the metabolism of ceramides, lipid molecules abundant in cell membranes that influence whether tumors are sensitive to certain chemotherapy agents.

Arognaute plays a key role in the RNA interference (RNAi) pathway that silences gene expression.

The drug, named Inclisiran, utilizes a technique called RNA interference therapy which targets, and switches off, a specific gene known to be responsible for elevated LDL levels.

These snippets trigger a natural cellular process called RNA interference, which dials down the levels of the polyphenol - degrading enzymes and prevents browning.

In contrast, other gene silencing drugs with names like RNA interference, siRNA or shRNA, need to be injected directly into the substance of the brain and don't spread very far without help.

Using genome - scale RNA interference (RNAi) screening and other high - throughput methodologies to uncover the functions of noncoding RNAs in the mammalian system, the McManus Lab has generated and characterized many small (micro) RNA conditional knockout mice.

Background: Small non-coding RNAs, including miRNAs, and gene silencing mediated by RNA interference have been described in free - living and parasitic lineages of flatworms, but only few key factors of the small RNA pathways have been exhaustively investigated in a limited number of species.

Scientists devised a powerful algorithm that improves the effectiveness of research technology harnessing RNA interference...

The research, published in the journal Nature, described the use of RNA interference (RNAi) technology to silence genes involved in the metabolism of cholesterol read more

In 2006, UMMS's Craig C. Mello, PhD, Howard Hughes Medical Institute Investigator and the Blais University Chair in Molecular Medicine, was awarded the Nobel Prize in Physiology or Medicine, along with colleague Andrew Z. Fire, PhD, of Stanford University, for their discoveries related to RNA interference (RNAi).

The Center for RNA Interference and Non-Coding RNAs (RNA Center), established under the Red and Charline McCombs Institute for the Early Detection and Treatment of Cancer, is a unique collaborative initiative among MD Anderson Cancer Center, Baylor College of Medicine, the University of Texas Health Science Center at Houston, Rice University and the University of Houston that will focus on gaining insights into the roles of newly discovered RNAs in cancer initiation, progression and dissemination.

short interfering RNAs (siRNAs)-- small, double - stranded molecules that are used in RNA interference to prevent the translation of genes into proteins.

The projects will provide training in: current molecular biology techniques (including RNA interference, genetic transformation, analyses of gene expression); cell biology techniques (cell culturing, cell transfections, imaging); protein biochemistry (2D electrophoresis, protein functional analyses); and bioinformatics (structure predictions, phylogenetic analyses; molecular interactions).

Based on their new phylogenomic maps, the researchers believe that RNA interference played a large role in the separation of monocots — plants that have a single seed leaf, including orchids, rice, and sugar cane — from other flowering plants.

One such evolutionary signal is RNA interference, a process that cells use to turn down or silence the activity of specific genes.

RNA interference of fascin reduced the number of filopodia, and remaining filopodia had abnormal morphology with wavy and loosely bundled actin organization.

Bernstein et al. «Role for A Bidentate Ribonuclease in the Initiation Step of RNA Interference», Nature, 409: 363 - 366, 2001.

We studied the remodeling of cytoskeleton networks during invadopodia formation and elongation using ultrastructural analysis, spatial distribution of molecular markers, and RNA interference silencing of protein expression.

Using RNA interference (RNAi), first author Richard Possemato targeted these genes in human breast cancer cells implanted in mice.

RNA interference further supported these results.

The 2006 Nobel Prize in Physiology or Medicine recognized the discovery RNA interference (RNAi), a basic mechanism of gene regulation that also provides an important new tool for functional genome analysis.

«Even more surprising, RNA interference also played a major role in the emergence of flowering plants themselves,» said Rob Martienssen, Professor and HHMI - GBMF Investigator at Cold Spring Harbor Laboratory.

RNA interference (RNAi)-- a revolutionary technique for gene silencing.

The protein, Argonaute - 2, is a key player in RNA interference, a powerful cellular phenomenon that has important roles in diverse biological processes, including an organism's development.

Cenix BioScience is a contract research organization focused on the discovery and pre-clinical development of novel therapeutics, specializing in advanced applications of RNA interference (RNAi) gene silencing combined with high content phenotyping in cultured cells in vitro and in animals in vivo.

We first designed a protocol for RNA interference (RNAi) to induce knockdown of sema2a.

RNA interference could stop those proteins from being produced and prevent varroa mites from harming bees.

The potential of a gene - silencing technique called RNA interference has long enticed biotechnology researchers.

In 2008, Jin and coworkers published in Nature Biotechnology their discovery that certain antibiotics called fluoroquinolones (ciprofloxacin is one) can make the RNA interference process work more efficiently — in general.

The technology uses a naturally occurring process called RNA interference.

This «RNA interference» tactic hijacks the natural machinery inside the cell that microRNAs use.

Joshua - Tor made her mark on structural biology with the solution of Slicer, an Argonaute protein that performs the enzymatic slicing of messenger RNA to carry out the process of RNA interference (RNAi).

Most dramatically, they've employed the use of RNA interference (RNAi), a technique that can knock out the function of individual genes.

The team is taking several approaches to inhibit HIF - 1 activity, including RNA interference, dominant negative constructs, and small molecule inhibitors.

The precision of the RNA interference process translates in better predictability of the biological effects of siRNA based drugs.

Silence Therapeutics develops a new generation of medicines by harnessing the body's natural mechanism of RNA interference, or RNAi, within its cells.

When Filer and coworkers used RNA interference (RNAi) to knock down the amount of the largest subunit of Pol III, rpc - 1, in C. elegans, the worm lived longer.

Our multidisciplinary approach includes transgenesis, real time imaging, multi-parameter flow cytometry, transcriptomics, RNA interference, proteomics and single cell methodologies.

P0051: Transcriptome Analysis of Bemisia tabaci during Tomato yellow leaf curl virus (TYLCV) Acquisition and RNA Interference to Manage Whitefly - transmitted Viruses

Our drug candidates harness a naturally occurring mechanism known as RNA interference, which is able to selectively inhibit gene expression

The researchers used a technique called RNA interference (RNAi) to screen a group of genes known to be involved in animal development, in order to study the signaling mechanisms that regulate whether the animal would produce a head or tail during regeneration.

Multimedia Resources include educational websites, videos, and apps, which cover basic heredity, genetic disorders, eugenics, the discovery of the structure of DNA, the human genome, cancer, neurobiology, plant genetics, RNA interference, epigenetics, and bioinformatics.