Sentences with phrase «rna isoform»

In the context of the current study, TRAF6's regulation of RNA isoform expression is important to the function of hematopoietic cells and reveals another dimension to how cells respond to infection, Starczynkowski said.

Consequently, this RNA isoform is not transported to the dendrites for translation.

More than half of mammalian genes generate multiple messenger RNA isoforms that differ in their 3 ′ untranslated regions (3 ′ UTRs) and therefore in regulatory sequences, often associated with cell proliferation and cancer; however, the mechanisms coordinating alternative 3 ′ - UTR processing for specific mRNA populations remain poorly defined.

Not exact matches

The reason it's called MGF — mechano growth factor — is that the mRNA [messenger RNA] of isoform 4 is elevated when mechanical stress is applied to muscle tissue.

(Mixture - of - Isoforms) for isoform quantitation using RNA - Seq is a probabilistic framework that quantitates the expression level of alternatively spliced genes from RNA - Seq data, and identifies differentially regulated isoforms or exons across Isoforms) for isoform quantitation using RNA - Seq is a probabilistic framework that quantitates the expression level of alternatively spliced genes from RNA - Seq data, and identifies differentially regulated isoforms or exons across isoforms or exons across samples.

We thus confirmed that the predominant expression of Boule during reproductive development is in the adult testis, including a testis - specific isoform, and also identified previously unreported low levels of Boule RNA in mouse ovaries.

We replaced exon 3, which encodes a part of the RNA binding domain and is present in all Boule isoforms (Figure 3C), with a lacZ - neo vector through homologous recombination in embryonic stem cells.

However, although many thousands of alternatively spliced transcripts are routinely detected in RNA - seq studies, reliable large - scale mass spectrometry - based proteomics analyses identify only a small fraction of annotated alternative isoforms.

CCDC66 is evolutionarily conserved in different vertebrate species and exhibits a complex pattern of differential RNA splicing resulting in various isoforms in the retina.