Sentences with phrase «rna messages»

RNA messages act like recipes telling the cell exactly what ingredients to use to make the protein.
Both of these proteins were found to promote cell quiescence by blocking other RNA messages that instruct the cell to start dividing.
There is no evidence that low levels of variant RNA messages resulting from failure to terminate some messages at the intended to termination point have any deleterious effect.
The promoter is the place at which are in a message starts being transcribed from the gene, and RNA messages are the means by which h genes can influence organism's ability to make proteins.
RNA interference, or gene silencing, is a way to destroy specific RNA messages so that a particular protein is not made.
A natural process called nonsense - mediated decay, or NMD, provides cells with the ability to detect errors in the coded RNA messages, called transcripts, that are copied from DNA when genes are activated.
If you imagine the female egg cell (and later, the fertilized egg) as a spherical planet with its own intrinsic biological geography, then certain characteristics of that cell — the location of protein molecules or RNA messages or biochemical traits like pH or even the internal connective structures called microtubules — will be more prominent in certain regions, like one hemisphere as opposed to the other, or near the surface rather than near the core.
Recent advances in single - cell genomics technology has made it possible to separate individual cells from different tissues and organs, and measure the sets of RNA messages — called the transcriptome — which help give each cell its own identity.
They also searched for sequences that enhance the efficiency of translation, when RNA messages are interpreted to build products such as protein molecules.
They discovered that IGF2BP3 binds to and stabilizes hundreds of leukemia - promoting RNA messages and consequently increases how much protein is made, resulting in an environment that is conducive to leukemia cell growth.
RNA messages are copies of small snippets of DNA that move out of the cell nucleus to be converted into proteins.
Rao and the research team found that it plays an important role in the development of the MLL - rearranged subtype of leukemia by regulating various RNA messages that contribute to the disease.
A specific protein called IGF2BP3 stood out due to its pervasiveness in the cells and its ability to bind to RNA messages within the cell.
They found that wtf genes made two different RNA messages - a short message (which encodes the poison) and a long message (which encodes the antidote).
Then the embryo's own DNA starts to make its own RNA messages.
In most cases both alleles are active and transcribed by the cells into an RNA message.
They can do this in various ways, but the new pictures are about one way in particular: events occurring after the attachment of the machinery to an RNA message (mRNA) copied from a gene.
They also expressed lower levels of an RNA message that controls the expression of a family of proteins called SOC, known to inhibit the migration of hematopoietic stem cells.
The researchers saw a remarkable sight: a strand of DNA transcribed by a little glob of the enzyme RNA polymerase into a genetic RNA message, ready to be translated into a protein.
EJCs are like chapter marks or tags deposited in the cell's nucleus as a gene's copied RNA message is edited, or spliced.
«We only want to dislodge or replace the EJC at one spot in the gene's spliced RNA message,» explains Krainer.
A molecular machine that makes proteins using the genetic instructions in RNA message molecules
17:17 - Using RNA sequencing, Brivanlou has identified 4 new RNA message molecules for huntingtin in embryo cells.
Ultimately, cells use this RNA message as instructions for constructing a protein — the huntingtin protein.
Researchers will have to bear in mind that some of the detrimental huntingtin protein may come from a shorter RNA message, which may be missed by some gene - silencing drugs.
Studying mice, Bates» team has found that the splicing step, where the non-coding gibberish is removed from the RNA message, goes wrong if the huntingtin RNA is expanded, as it is in Huntington's disease.
Bates» team showed that a protein usually responsible for the editing of RNA message molecules actually sticks to expanded huntingtin RNA, but not to normal huntingtin RNA.
One possible implication of this work is for so - called «gene - silencing» therapies for Huntington's disease, which aim to reduce production of the huntingtin protein, by sticking to its RNA message molecules and telling cells to get rid of them.

Not exact matches

The message in the RNA molecule is then «translated» into a particular protein (enzyme).
They first do this by destroying the maternal RNA (DNA messages) that originally came from the maternal genes in the egg.
Since messenger RNA is nothing but the imprint of the gene whose message it is carrying, it is possible to use it to chemically generate the DNA sequence or gene it corresponds to.
RNA carries messages from DNA, huddled in the nucleus, to the rest of the cell so that proteins can be produced locally.
What makes these tangles distinct is that they sequester proteins involved in RNA splicing, the process by which instructional messages from genes are cut and pasted together.
Looking for plants that tolerate stress Inside the cells of a corn plant, tiny molecules called RNA relay messages to help with cell activity.
The element produces a physical loop in the RNA, Gladyshev explains, which interacts with ribosomes and changes UGA's message.
First, enzymes zip along DNA, producing ticker - tape - like messages called messenger RNA.
Scientists looked at messenger RNAs, which carry genetic messages from DNA to help make proteins — long chains of amino acids that form structural components of body tissue such as muscle and hair.
Doing the screen involves using short pieces of RNA, called small hairpin RNAs, which are inserted into the cell and are able to halt messages from specific genes, keeping the genes from making proteins.
Active genes produce molecular messages called RNA through a process called transcription.
Because RNA carries the genetic message from DNA to the cell's proteinmaking factories, or can directly perform acts such as gene regulation, it, too, is an appealing target for therapies.
RNA was once thought to be a mere middleman, carrying genetic messages from the DNA in the nucleus out to cellular structures called ribosomes, where it directs the production of proteins.
Activation of a gene induces a cell to make an RNA copy of its code, edit unneeded segments out of that message, and splice together a final version of the message that provides cellular factories (ribosomes) with a template to make one specific protein.
The details are technical, involving how far — how many coded RNA letters — a premature stop signal occurs relative to a location on the message that serves as a loading site for an EJC (exon junction complex).
However, we now know that there's more to it than that, and there are several genetic diseases where the RNA is directly poisonous to cells, rather than simply carrying a harmful message.
A way of silencing genes using specially designed molecules of RNA — like DNA but made of only a single strand — that target the message molecules in cells and tell them not to make a certain protein
What these groups are attempting basically is «gene silencing», with a twist - it's aimed directly at the DNA, rather than targeting a «message molecule» called RNA.
Human Argonaute - 2 (hAgo2) is known as «slicer» for its unique ability among the 4 human Argonaute proteins to directly cut messenger RNA — which carries the information coded in genomic DNA to make a protein — and thus disable «messages» generated from genes.
While messenger RNAs carry genetic messages outside a cell's nucleus, microRNAs perform a nearly opposite function — preventing gene expression.
Effects of 3 diets with various calcium contents on 24 - h energy expenditure, fat oxidation, and adipose tissue message RNA expression of lipid metabolism - related proteins
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