Sentences with phrase «rna molecules»

A type of gene silencing treatment in which specially designed RNA molecules are used to switch off a gene

The new technique works by taking advantage of the fact that RNA molecules are passed between the infected corn and the Aspergillus fungus.

Knowing this, the UA researchers modified the corn plants» genetic code so it produces hairpin - shaped RNA molecules within the kernel, and when the fungus takes hold, these are sent into it.

One group of small, non-coding RNA molecules could serve as a marker to improve cancer staging and may also be able to convert some advanced tumors to more treatable stages, report a University of Chicago - based research team in the April 1, 2008, issue of the journal Genes & Development.

Around that time, the RNA field had reached a pinnacle, so Doudna pivoted to focus on RNA - protein interactions and the function of RNA molecules in cell biology.

RNA structure prediction The recent interest in RNA, specially non-coding RNA molecules, has prompted us to develop a series of tools for the alignment of RNA structures and the prediction of their functions.

Like DNA, RNA molecules are often folded.

The unfolded RNA molecules can then be guided through the joint channel to the Exosome.

But introducing large amounts of targeted RNA molecules into the environment is not.

They unwind RNA molecules or, respectively, proteins and guide them to the active centers of the specific degradation machinery.

The technique allows researchers to directly observe individual messenger RNA molecules (mRNAs) as they are translated into proteins in living cells.

That diet, a mixture of pollen and honey called «beebread,» is shot through with a special kind of microRNA (miRNA), noncoding RNA molecules that help regulate gene expression.

The researchers made use of RNA interference, a natural process whereby RNA molecules inhibit gene expression.

«The Ski complex feeds RNA molecules to the Exosome,» explains the biochemist.

To be degraded by the Exosome, RNA molecules have to be unfolded first — this task is executed by the Ski complex.

Any errors that occur during the synthesis of RNA molecules or unwanted accumulation of RNAs can be harmful for the cell.

The technique, developed by two separate research groups, one at Princeton led by Thomas Gregor, associate professor of physics and the Lewis - Sigler Institute for Integrative Genomics, and the other led by Nathalie Dostatni at the Curie Institute in Paris, involves placing fluorescent tags on RNA molecules to make them visible under the microscope.

Ribozymes are RNA molecules with enzymatic activities.

The long and short RNA molecules overlapped with each other, as well, which means that the shorter molecules may be fragments of the longer ones, the researchers report in a paper published online today by Science.

The other new Common Fund initiative launching in 2013 will focus on RNA molecules that cells secrete to communicate with each other.

Tiny RNA molecules may be key players in cancer, according to three reports published in the 9 June Nature.

MicroRNAs (miRNAs) are small non-coding RNA molecules that play a crucial role in regulating gene expression in animals and plants.

They identified a set of long RNA molecules, which they dubbed PALRs (for promoter associated long RNAs), and a set of short ones (PASRs).

Cells make proteins by copying genes into RNA molecules, which serve as templates for building proteins.

Researchers know that the cells of species such as yeast, flies and humans make far more RNA molecules — copied from DNA — than they seem to need.

What that indicates, Gingeras says, is that the long RNA molecules are being copied from near the front of a gene, where they interfere with the gene's production until they are reduced to smaller pieces.

In 2015, Russell and his collaborators showed that a vent surrounded by an approximation of Earth's early ocean could link RNA molecules into a two - part strand, and Barge says they will soon release more results.

The researchers showed that Hsp90 inhibition reduced production of AR - V7 through a new and unexpected mechanism of action — by changing the way that messenger RNA molecules carrying the code for AR - V7 are processed.

Scientists have taken a big step toward developing therapies based on naturally occurring tiny RNA molecules called microRNAs.

«Our research revealed how small RNA molecules can work with other cell signals called transcription factors to generate specific types of neurons, in this case motor neurons.

Biologists suspect that life as we know it emerged from an «RNA world» in which RNA molecules could copy themselves and store genetic information.

Peter and his team discovered sequences in the human genome that when converted into small double - stranded RNA molecules trigger what they believe to be an ancient kill switch in cells to prevent cancer.

Special RNA molecules stop the synthesis of proteins from a target gene (top); other genes are unaffected (bottom).

In RNAi, double - stranded RNA molecules target a messenger RNA with a corresponding sequence and cause it to be chewed up, thus preventing the messenger RNA from making its protein.

Drugs made from synthetic DNA are tailored to grab onto these mutant messenger RNA molecules, binding to them and preventing them from churning out toxic proteins.

Small RNA molecules originally developed as a tool to study gene function trigger a mechanism hidden in every cell that forces the cell to commit suicide, reports a new Northwestern Medicine study, the first to identify molecules to trigger a fail - safe mechanism that may protect us from cancer.

The RNA molecules direct which proteins the cell produces, so the RNA sequences show how tumor cells behave differently to normal cells.

Their technique, called serial analysis of gene expression (SAGE), works by tracking RNA molecules back to their DNA sources.

Cancer cells treated with the RNA molecules never become resistant to them because they simultaneously eliminate multiple genes that cancer cells need for survival.

In September, Alnylam Pharmaceuticals announced that its small RNA molecules silenced the gene that causes the progressive disease hereditary ATTR amyloidosis in a successful phase III trial.

Like infinitesimally small Lego blocks, the nucleic acids that make up RNA connect to each other in very specific ways, which force RNA molecules to twist and loop into a variety of complicated 3D structures.

When all goes well, messenger RNA molecules in our cells produce the good proteins that are essential to life.

Scientists aiming to turn RNA molecules into therapies are entering this year with new optimism, after years of frustration.

And one of the interesting ones is [that] the clay minerals will help membranes to assemble; so it turns out there is a very common clay mineral that it previously had been looked out by prebiotic chemists and shown to help RNA molecules to assemble.

Xi Chen at Nanjing University in China and colleagues have now found that beebread contains lots of small RNA molecules called microRNAs that regulate the expression of genes.

Researchers at Sanford - Burnham Medical Research Institute have identified a set of RNA molecules that are detectable in tissue samples and urine of prostate cancer patients, but not in normal healthy individuals.

These small RNA molecules must be trimmed from long hairpin - loop structures, raising a question: How do cells know which RNA loops need to be processed this way and which don't?

These RNA molecules are copied from portions of the genome that do not «code» for proteins.

The researchers believe that they have identified a group of RNA molecules — known as long noncoding RNAs (lncRNAs)-- that hold the potential for serving as better prognostic markers for prostate cancer.

More recently, similar RNA molecules have been identified in cellular systems, though the sequences tend to be much shorter and function in a different manner.