«It would be stupendous to see the data out of Moderna,» says Paul Agris, an analytical biochemist at the State University of New York in Albany's RNA Institute who has spent decades studying the consequences of modifying
RNA nucleosides.
Not exact matches
The scientists suggest that flavivirus helicases could have evolved a conserved motor to convert chemical energy from
nucleoside triphosphate to mechanical energy to unwind their genetic material, but the motors of the flaviviruses move in distinct ways to access their genomic
RNA.
Kariko, K., Buckstein, M., Ni, H. & Weissman, D. Suppression of
RNA recognition by Toll - like receptors: the impact of
nucleoside modification and the evolutionary origin of
RNA.
It does this, Ebright said, by mimicking a
nucleoside - triphosphate, one of the «building blocks» of
RNA that is essential for life.
REPAIR has the ability to target individual
RNA letters, or
nucleosides, switching adenosines to inosines (read as guanosines by the cell).