Sentences with phrase «rna viral sequences»

Nineteen of the species, including a squirrel, a small bat, a zebrafish, and a human had RNA viral sequences embedded in their DNA.

Unlike the previous studies that focused on certain species or a particular RNA virus, Skalka went broad: She and her colleagues surveyed every vertebrate genome available, 48 in all, and looked for hints of 5666 RNA viral sequences from 38 known families and nine genera that were unclassified.

Not exact matches

Here's how it works: When a bacterium encounters DNA from a virus, it makes a strand of RNA, a molecular cousin to DNA, that matches the sequence of the viral DNA, known as a guide RNA.

The team designed DNA circuits that simultaneously test for 24 distinct regions of viral RNA — more than would have been possible using only naturally occurring DNA sequences (Cell, doi.org/wn4).

Complete viral RNA genome sequencing of ultra-low copy samples by sequence - independent amplification

To identify the accumulated mutations that restored viral fitness, the researchers sequenced the viral RNA using a supersensitive method called PrimerID sequencing, which enables tracking of all individual viral genomes so that any relevant mutations can be spotted.

Collins estimates it cost just $ 21 to develop the litmus sensor — the cost of buying the sequences of DNA that detect the viral RNA.

The viral genome sequence also enabled an international group of researchers, including Fouchier and Drosten, to quickly devise diagnostic tests that look for short, characteristic stretches of the virus's RNA.

Genetic sequencing identified the RNA genome as a member of the insect - infecting Cripavirus genus, but the DNA viral genome was more mysterious: It was unlike any sequenced present - day viruses, but distantly related to plant - infecting geminiviruses.

An article published on June 26th in PLOS Pathogens now reports that a mini antibody called 3D8 scFv can degrade (or chew up) viral DNA and RNA regardless of specific sequences and protect mammalian cells and genetically manipulated mice against different viruses.

As they report in two new studies, the pair and their colleagues constructed viral vectors, each one containing an RNA molecule designed to shut down a gene with a complementary sequence.

Currently, detection of viral RNA through RT - PCR and / or sequencing can distinguish between ZIKV and other mosquito - borne viruses only during the first few days after the onset of symptoms.

I will review recent advances in the use of nanopore sequencing for clinical microbiology and human genetics, including our collaborations on viral and bacterial diagnostic sequencing, real - time surveillance, direct RNA and human whole - genome sequencing, and discuss the opportunities and barriers around moving to sequencing as a routine test in the clinic.

Contains sequences necessary for activation of viral genomic RNA transcription.

IRES was originally discovered in poliovirus RNA, where it promotes translation of the viral genome in eukaryotic cells.1, 2 Since then, a variety of IRES sequences have been discovered - many from viruses, but also some from cellular mRNAs.

To characterize their viral genomes in greater depth, we analyzed RNA extracts from these 3 samples by unbiased next - generation, or «deep» sequencing.

Analysis of viral genomic and human mitochondrial sequences revealed that all previously characterized XMRV strains are identical and that the archival RNA had been contaminated by an XMRV - infected laboratory cell line.

A pilot experiment with 125 patient plasma samples was performed to investigate the optimal method for isolation of HIV - 1 viral RNA for long amplicon genome sequencing.

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