In laboratory animals, both DNA viruses (polyomavirus and SV - 40 virus) and
RNA viruses (type C retroviruses) have been found to trigger osteosarcoma.
Distemper in dogs is a viral infection that is caused by a member of the Paramyxoviridae family of
RNA viruses that are similar to the viruses that cause measles, bronchiolitis, and mumps in man.
His current research interest at University of Rochester focuses on the molecular biology, pathogenesis, innate immune responses and vaccine development for
RNA viruses, mainly arenaviruses and influenza.
He next conducted post-doctoral research on the molecular biology of negative stranded
RNA viruses, mainly influenza A and B viruses, under the supervision of Dr. Adolfo Garcia - Sastre in the Department of Microbiology at the Icahn School of Medicine at Mount Sinai in New York, USA.
His research interest has been focused on the molecular biology, virus - host interaction and pathogenesis of positive - and negative - stranded
RNA viruses.
Nodaviruses and the polio - like CrPV belong to two different superfamilies of animal
RNA viruses.
Use of Unamplified RNA / cDNA — Hybrid Nanopore Sequencing for Rapid Detection and Characterization of
RNA Viruses
CVB3 is a type of picornavirus, a family of rapidly mutating small
RNA viruses that causes illnesses ranging from the common cold to pancreatitis to polio.
RNA viruses — a group that also includes HIV — change every time they replicate.
MOV10 Provides Antiviral Activity against
RNA Viruses by Enhancing RIG - I - MAVS - Independent IFN Induction
The new finding suggests that, when transmitted sexually, women are both more susceptible to contracting
RNA viruses and have a harder time clearing the infection from their systems.
In 1986, the organization's Microbiology - Virology department began work on a U.S. Army contract to study antiviral activity of compounds against exotic
RNA viruses.
The results of Reinisch's monumental effort were published in Nature in 2000 and provided novel insights about how double - stranded
RNA viruses make and deliver viral messenger RNA into the host cell.
These structures gave Peersen insight into how these single - stranded
RNA viruses work.
Application of Sequence - Independent Amplification (SIA) for Identification of
RNA Viruses in Bioenergy Crops, Bright Agindotan, Monday Ohonsi, Leslie Domier, Michael Gray, Carl Bradley, Journal of Virological Methods, 169 (1): pp. 119 - 128, October 2010.
In other
RNA viruses, such as poliovirus, there are rare cases of persistent infection lasting for several years in patients with compromised immune responses.
It is therefore likely that
RNA viruses can persist in some patients long after symptoms disappear, but that these individuals are rarely detected.
Costs and Benefits of Mutational Robustness in
RNA Viruses.
Teams have captured the protein shell of the measles virus, for example, the first in the family of
RNA viruses that includes rabies and Ebola.
Our results detected a DNA virus and two
RNA viruses that had not been previously reported in honey bees from the USA.
The potential correlation of IIV with CCD may previously have gone unnoticed because these are large DNA viruses, not the small
RNA viruses commonly considered to be the cause of most bee diseases.
A viral potluck For almost 40 years, scientists have worked to understand how
RNA viruses can have so many mutations and still be so successful.
Dr. Palese has more than 400 scientific publications that include research on the replication of RNA - containing viruses with a special emphasis on influenza viruses, which are negative - strand
RNA viruses.
The one big thing that's missing are the arenaviruses,
RNA viruses that include things like Lassa, for example.
Internationally renowned microbiologist, Peter Palese, PhD, pioneered the field of reverse genetics for negative - strand
RNA viruses, which allows the introduction of site - specific mutations into the genomes of these viruses.
Unlike DNA viruses, which contain two copies of their genetic information,
RNA viruses are single - stranded.
As a result, copying is sloppy, and so each new generation of
RNA viruses tends to have lots of errors.
This viral genetic jumble has given Marco Vignuzzi, a virologist at the Pasteur Institute in Paris, a way to predict the future evolution of
RNA viruses like chik.
Coffin says the discovery of NIRVs in mammals establishes that these and other
RNA viruses are ancient.
Filoviruses are
RNA viruses that don't carry the gene for reverse transcriptase, yet that hasn't stopped them from somehow leaving their mark.
Researchers long have believed that to accomplish this feat,
RNA viruses had to carry the gene for an enzyme, reverse transcriptase, to convert their RNA into DNA.
Their discovery of NIRVs in mammalian genomes corroborates a study in the 7 January issue of Nature in which John Coffin of Tufts University School of Medicine in Boston and colleagues reported that another group of
RNA viruses that lack reverse transcriptase, bornavirus, can integrate their genes into mammals.
But very little is known about its role in infectious diseases, such as the notorious
RNA viruses hepatitis, influenza and the common cold.
«Chemical tags affect ability of
RNA viruses to infect cells: Similar controls found in Hepatitis, Zika, Dengue, Yellow Fever.»
New research out of Duke University shows that
RNA viruses are littered with N6 - methyladenosine tags which affect the ability of these viruses to infect cells and, ultimately, their human hosts.
«We are trying to fill the knowledge gap between the infection and potential neurological defects,» says first author Hengli Tang, the team's virologist whose lab studies
RNA viruses like Zika, Dengue, and hepatitis C virus.
Retrotransposons — many of which were once
RNA viruses called retroviruses — are the copy - and - pasters.
A code hidden in the arrangement of the genetic information of single - stranded
RNA viruses instructs the virus how to pack itself within its outer shell of proteins.
Research from UW Medicine and collaborators indicates that a drug - like molecule can activate innate immunity and induce genes to control infection in a range of
RNA viruses, including West Nile, dengue, hepatitis C, influenza A, respiratory syncytial, Nipah, Lassa and Ebola.
These viruses are so - called
RNA viruses.
RNA viruses pose a significant public health problem worldwide because their high mutation rate allows them to escape the immune response.
«Our study exemplifies the utility of looking beyond phylogenetic criteria alone when conducting risk assessment for emerging
RNA viruses and the need to include functional, ecologic, and pathogenic analyses of animal reservoirs,» says Jan Felix Drexler, M.D., the study's corresponding author and a professor of medicine at the Institute of Virology at the University of Bonn Medical Centre in Germany.
Yellow fever is caused by an arbovirus of the family Flaviviridae, and is one of the smallest
RNA viruses isolated.
The viruses that cause FMD (members of a diverse family of small
RNA viruses called picornaviruses) are not all that deadly; they can cause fatal cardiac arrest in young animals, but most adult animals recover.
RNA viruses can direct the copying of their own proteins without using DNA — a shortcut that generates both more copies and more errors, or mutations.
So - called
RNA viruses are rogues: smaller, fast - replicating shape - shifters, descended from a time that evolutionary biologists refer to as the RNA world, back near the base of life's tree, before today's DNA - based organisms evolved.
They searched the fluid for traces of RNA indicating the presence of different classes of retroviruses,
RNA viruses that, like HIV, copy their sequence into the genome of infected organisms.
(
RNA viruses use ribonucleic acid as their genetic material; examples include SARS, polio, and retroviruses like HIV.)
«Given that the job of RNase L was to chew up
RNA viruses, we hypothesized the possibility of a novel RNA virus in our patients,» Mikovits says.
Bees infected with both the fungal parasite Nosema ceranae and with any one of a handful of
RNA viruses were much more likely to have come from hives on the decline than from healthy hives, researchers reported May 25 at a meeting of the American Society for Microbiology.