Sentences with phrase «ros generation»

This suggests that disease processes related to ROS generation may be ameliorated by an LCD that is associated with an increase in ketones.

Moreover, ROS generation was found treatment with 15d - PGJ2, and its cytotoxic effect could be reversed with N - acetyl - l - cysteine.

These observations suggest that ARE - regulated genes may be controlled by an intracellular ligand independent of ROS generation, electrophilic reactivity or elevation of Nrf2 levels in the cell.

It is believed that ROS generation subsequently leads to rapid activation of EGFR - Ras pathway and its downstream molecules such as ERK1 / 2, AKT, etc. [4, 25 - 30].

Zaika and his team identified two specific enzymes, NOX1 and NOX2, which were responsible for ROS generation.

Using a variety of methods to induce somatic cells to become iPSCs, the researchers first found that in the early stages of reprogramming, the transformation was consistently accompanied by an increase in ROS generation.

Finally, the researchers discovered that ROS generation subsided as the iPSCs matured, and these mature stem cell colonies survive best in a cellular environment with low levels of ROS.

Not exact matches

Generation of ROS, a byproduct of the energy production and use, is normal as well, but, as with fission, too much is bad for the cell.

«Conversely, the overproduction of ROS impaired stem cell formation, meaning that optimal iPSC production occurs within a «Goldilock's zone» of free radical generation — too little or too much and reprogramming shuts down.»

However, excessive generation of ROS and / or a fall in antioxidant defences can lead to indiscriminate damage, resulting in cellular oxidative stress [27].

In prostate cancer cells the STAT3 - androgen receptor (AR) axis was inhibited by niclosamide and cell death in NSCLC was effected via c - JUN stress kinase and generation of ROS [39, 40].

Increased TBARS and ROS are markers for oxidative stress caused by increased generation of free radicals.

Exposure of tumor cells to clinically relevant low doses of ionizing radiation causes DNA damage and the generation of reactive oxygen species (ROS).

The generation of ROS during energy production increases with aging and increased inflammation levels.

Importantly, the enhanced Aß generation could be attenuated by ROS scavenging using the antioxidant vitamin C. However, very high concentrations much above therapeutical levels were needed.

Abnormal Krebs cycle and / or oxidative phosphorylation cause (s) not only glucose hypometabolism but also the increased generation of reactive oxygen species (ROS), oxidative damage, and programmed cell death such as apoptosis.

We all know how important regular exercise is for our physical, mental and emotional health, but strenuous anaerobic exercises have been reported to enhance the generation of reactive oxygen species (ROS); which in turn can contribute to both the initiation and progression of muscle fibre injury as well as impaired muscle performance.4 Green Tea Extract (GTE) however has been clinically proven to prevent oxidative stress induced by high - intensity training and subsequent muscle breakdown — once again thanks to its EGCG content.5

Inflammation in the intestines produces damaging reactive oxygen species (ROS) which initiate DNA damage, reduces oxygen flow to tissue and results in the further generation of pro-inflammatory cytokines and injury.

Install RO gear or evap gear and use existing natgas supplie to power turbine electric generation for system.

While there, she led a team of engineers developing next - generation robot hardware and software, including ROS, the PR2 and TurtleBot.