Sentences with phrase «rpe cell sheet»
The left column shows combined Nomarski and confocal images of the pigmented iPS - RPE cell sheet sections; adjacent are images of immunolabelling only.
http://journals.plos.org/ Not exact matches
The middle layer is a one - cell - thick sheet known as the retinal pigment epithelium, or RPE.
They then transform those iPS cells into RPE cells and form them into sheets in the lab.
A pilot study assessing the safety and feasibility of the transplantation of autologous iPSC - derived retinal pigment epithelium (RPE) cell sheets in patients with exudative (wet - type) age - related macular degeneration was launched in Japan in August 2013.
Various cell types have been examined for use in RPE cell replacement including immortalized cell lines, such as the human RPE cell line, ARPE19 [2], sheets of adult RPE [3], foetal RPE [4], RPE derived from human embryonic stem cells (HESC - RPE)[5]--[10] and many non-RPE cells lines [11]--[15].
iPS - RPE cells or sheets of cells were fixed for 30 min with 4 % paraformaldehyde in 0.1 M phosphate buffer.
Cells were cultured in human foetal RPE medium [30] where, within 13 days, they formed a pigmented monolayer with characteristic RPE cobblestone appearance similar to that observed in human post-mortem RPE sheets and HESC - derived RPE cells [9](Fig.Cells were cultured in human foetal RPE medium [30] where, within 13 days, they formed a pigmented monolayer with characteristic RPE cobblestone appearance similar to that observed in human post-mortem RPE sheets and HESC - derived RPE cells [9](Fig.cells [9](Fig. 1B).