Sentences with phrase «reactivate it -lsb-»

«Instead, some cancer cells seem to reactivate and corrupt programs that govern fetal tissue stem cell function, including programs from their neighboring cells that constitute the surrounding fetal stem cell landscape, or microenvironment.»

But it turns out that a process called somatic cell nuclear transfer (SCNT) can sometimes reactivate genes.

«Then we can ask: Does a mouse have similar pathways, and can it reactivate dormant abilities that are perhaps latent in its genome?»

Knox developed a chemical compound that can be injected into the gland to mimic the signals from the nerve cells and reactivate the repair process with the stem cells.

A drug that could reactivate p14 ARF would reactivate p53, thereby reinvigorating the cell's defenses.

BK: As you stated, all of these genes are present in the human genome, but they are regulated differently, so finding mechanisms or therapies that can reactivate them is critical.

, Dr. Jacqueline Shields, University of Cambridge, United Kingdom Speaker: Jacqueline Shields, University of Cambridge, United Kingdom Host: Postdoc Network DKFZ Outline of the talk The recent success of immunotherapy platforms to harness and reactivate the immune response represent a major therapeutic advancement, however, many patients still fail to respond or do not see lasting benefits.

In this study, the researchers found that the drug 5 - aza - 2 «deoxycytidine (aza - CdR) can inhibit HIV methylation and cause the virus to reactivate.

«Now, with the help of gene therapy and stem cells we can help reactivate the body's response to hypoxia and save limbs.»

By understanding this «latency» effect, researchers can identify ways to reactivate the virus and enable complete clearance by current or future therapies.

Researchers are exploring two main strategies to tackle this problem ---- reactivate and destroy the latent virus (called «shock and kill») or find a way to silence it for good.

Telomerase is turned off in most human cells, but cancer cells often must reactivate it so that they can keep dividing like crazy.

In this way they were able to reactivate the senescence program and stop the growth of the breast cancer cells.

In a paper published today in the journal Science, researchers at MIT reveal that they were able to reactivate memories that could not otherwise be retrieved, using a technology known as optogenetics.

When they returned one day later and attempted to reactivate the memory using an emotional trigger, they could find no trace of it.

Aza - CdR and HDAC inhibitors do not synergistically reactivate latent HIV - 1 Latent HIV - 1 reactivation in the indicated J - Lat cell lines treated with aza - CdR, VPA, aza - CdR plus VPA, SAHA, or aza - CdR plus SAHA.

Our findings may prove useful in the development of novel therapies to efficiently reactivate latent HIV - 1, thus making it susceptible to current drug therapies.

The combined use of therapeutic vaccination and specific drugs that can reactivate latent reservoir virus (Kick and kill strategies) hold the promise to achieve a functional cure for HIV infection.

«In other words, surprisingly small changes in stress can reactivate certain faults in the region and cause earthquakes,» DeShon said.

In people with suppressed immune systems, such as cancer patients, the parasite can reactivate and cause neurological damage and even death.

This enables scientists to genetically modify phage genomes systematically, provide them with additional functionality, and finally reactivate them in a bacterial «surrogate» — a cell - wall deficient Listeria cell, or L - form.

Species often dump genes that they no longer use, he notes, but these genes must have stuck around for Crotoniidae to reactivate them.

For instance, Twitter users affiliated with IS who were blocked or banned at one point are often able to reactivate their accounts and use their experience as a demonstration of their commitment.

In the second study, reported online today in Nature, researchers were also able to reactivate an old memory in mice.

Additionally, the researchers also discovered a possible metabolic on / off switch that could reactivate brown fat.

The virus can reactivate because immunity to chicken pox fades with time.

The Reunion outbreak is «an opportunity to reactivate the research effort and to bring the vaccine to licensure,» says Colonel David Vaughn, who heads the infectious disease research program at the U.S. Army Medical Research and Materiel Command.

In vitro genetic selection was used to identify mutations that reactivate a virtually inactive sunY deletion mutant.

Mayford could then selectively reactivate those cells whenever he wanted, simply by giving the mouse a drug known as clozapine - N - oxide (CNO), which interacts with hM3Dq.

As Japanese officials consider whether and when to reactivate most of the country's 54 nuclear plants, a year after the Fukushima reactor disaster, they continue to face challenges to public confidence in the nuclear industry and its regulator.

G2 - arrested quiescent stem cells reactivate more readily than G0 cells and are regulated by the pseudokinase Tribbles.

While this process is essential during development, it appears to be hijacked in diseased or traumatic conditions to reactivate and accelerate neuron degeneration.

In the United States, tuberculosis remains an important preventable disease, including active tuberculosis infection, which may be infectious, and latent infection (LTBI), which is asymptomatic and not infectious but can later reactivate and progress to active disease.

Now the WHO is predicting that by the year 2000 infection with HIV will reactivate TB in a million people.

In the new study, expanding upon what scientists previously understood about intrinsic immunity, the researchers found that cells can subsequently respond to latent HCMV by employing other cellular proteins called lysine demethylases to reactivate the virus.

«Once a liver cell is infected, the viral genome persists inside the nucleus, and that can reactivate later,» says Bhatia, the John and Dorothy Wilson Professor of Health Sciences and Technology and Electrical Engineering and Computer Science.

«A key question now is to know how the human of the 21st century can reactivate his animality and animalize himself anew when all Western thought since the Greeks tells him that he is human precisely because of this rupture with animality,» Lestel suggests, building on his critique of the very philosophical foundations of the ethological tradition.

These viruses have the potential to reactivate if the immune system is suppressed.»

Antidotes to OP exposure reactivate AChE by directly breaking its chemical bond with the OP.

We ¿ re getting an idea of what the brain uses as its rules for picking out cortical memory traces to reactivate and bring into our conscious mind, and we ¿ re trying to see across wake - sleep cycles how that process happens.

This seems to suggest that «to effectively generate a plausible image of the future, subjects reactivate images (e.g., visual - spatial context),» the researchers write in a paper published online January 1 in Proceedings of the National Academy of Sciences USA.

At the interface of these innovative neuroprosthetic protocols are implantable electrodes that can read neural activity, stimulate nerves, and bypass nerve injury to reactivate biological function.

Slumber is known to improve recall in creatures from fruit flies to humans, and the reigning theory among neuroscientists has been that the waves of brain activity during deep sleep reactivate neurons that were triggered during the day, strengthening neuronal connections and cementing them into solid memories.

These cells had previously been shown to reactivate estrogen signaling in order to acquire drug resistance.

«The effect of the precursors that boost NAD is to counteract the decline that occurs with normal aging, to reactivate SIRT1, and to restore function in endothelial cells to give rise to more blood vessels.»

It is not necessary to reactivate but we do recommend you keep your profile at AAAS up - to - date and check to make sure all of your IP addresses are current.

«It is our hope that Dr. Yin's research will lead to additional potential therapeutic agents like ZF143 to reactivate mechanisms for the repair and regeneration of damaged heart muscle tissue in humans.»

These targets include the limbic system, a group of evolutionarily old structures deep in the brain, «which is where viruses like to reactivate,» Jacobson explains.

Finding drugs that reactivate the tumour suppressor protein p16 silenced by methylation would also be a boon.

They also identified a drug, 5 - aza - 2 «deoxycytidine, that inhibited this restriction process and caused HIV to reactivate and replicate.