Sentences with phrase «rearrangement studies»
Duration of Symptoms Does Not Correlate with Results of T - cell Gene Rearrangement Studies in Patients Evaluated for Cutaneous T - Cell Lymphoma.
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The group's next steps will be to study whether the dynamic rearrangements of chromatin might be a much more general phenomenon in mouse tissues, controlling other physiological functions.
Although the research doesn't clarify the reason for the rearrangement, the authors suggest that further studies could explain the shift.
Then she applied her expertise to humans, studying chromosomal rearrangements in leukemia cells.
This study showed the two subtypes have different genetic origins and involve a dramatically different number of chromosomal rearrangements, mutations and other gene variations.
Now, through an unexpected observation and a meticulous study of patients seen at Brigham and Women's Hospital, BWH investigators have added a fourth cause to the list: a genetic rearrangement in the ALK gene, observed in three patients with peritoneal mesothelioma.
Dorothy Romanus, lead author of the study, states «this analysis supports the value of multiplexed testing for EGFR and ALK gene rearrangements followed by molecularly - guided therapy in decisions surrounding coverage of related testing and targeted therapy.
«This study demonstrates the value of testing lung cancer tissue for an ALK rearrangement, and it underscores the potential of cancer genomics to target cancer treatments to each patient,» says the study's senior author, Pasi A. Jänne, MD, PhD, who is the director of the Lowe Center for Thoracic Oncology of Dana - Farber.
Ceritinib provides longer progression - free survival than chemotherapy in crizotinib - pre-treated patients with non-small-cell lung cancer harbouring an ALK rearrangement, according to results of the phase III ASCEND - 5 study presented at the ESMO 2016 Congress in Copenhagen.
Although «genomic rearrangements have been associated with autism for awhile,» finding more of the novel changes is «quite exciting for the field,» says Simon Gregory, an associate professor of medical genetics at Duke University's Center for Human Genetics, who was not involved in the study.
«In this study, we showed that by just doing a rearrangement of the top electrode into a fractal geometry then we can stimulate the neurons within the open - circuit voltage of silicon photodiodes.»
A study from the Wellcome Trust Sanger Institute, the Wellcome Trust Centre for Human Genetics and their collaborators has identified a genetic rearrangement of red blood cell glycophorin receptors that confers a 40 per cent reduced risk from severe malaria.
«Natural resistance to malaria linked to variation in human red blood cell receptors: First study to identify protective effect of glycophorin gene rearrangements on malaria.»
Results from these and other studies are yielding important insights into the cooperativity effects in hydrogen bonding, aqueous solvation, and hydrogen - bond network rearrangement dynamics, which promise to enhance our understanding of solid and liquid water behavior.
A new study shows that structural variations in DNA are key to individual differences, indicating that all parts of the genome are prone to rearrangement
The growth of long facial feathers, creating the appearance of muffs and beards on chickens, is caused by a chromosomal rearrangement affecting a gene involved in feather development, report Xiaoxiang Hu of the China Agricultural University in Beijing and colleagues, in a new study published on June 2 in PLOS Genetics.
The study also demonstrates, contrary to what many suspected, that there was no rearrangement of DNA that would have prevented such cells from starting over.
Liu says it has been technically difficult to study the mechanism for B cell rearrangement in the developing immune system.
In order to answer this question, the biologists have studied an array of more than 500» 000 chromosomal rearrangements already characterized in a wide range of tumors.
Therefore, herpesviruses are an attractive model to study viral genome evolution at the levels of gene duplication and protein domain rearrangement.
Cytoskeletal rearrangements in human red blood cells induced by snake venoms: light microscopy of shapes and NMR studies of membrane function.
CCG uses high - throughput techniques to identify and study mutations, large rearrangements of the genome, increases and decreases in DNA copy number, chemical modifications to DNA, and changes in the expression of RNA and proteins.
Studies on horizontal gene transfer and enzymemediated DNA rearrangements lead him to postulate a theory of molecular evolution according to which nature cares actively for the promotion of biological evolution by using products of specific evolution genes as well as several intrinsic non-genetic elements.
Therefore, tests that detect TRB clonal rearrangements can be useful in the study of B - and T - cell malignancies.
Our NGS kits are used to detect clonal gene rearrangements, somatic hypermutations and for the study of MRD.
A new study published today describes how a complex genomic rearrangement causes a fascinating phenotype in chickens.
In a previous study, we showed that genomic rearrangements of up to one million base pairs can be generated by direct injection of CRISPR / Cas9 reagents into mouse zygotes.
In a concurrent study, bacteria with different DNA arrangements were grown in the lab, and SMRT technology was used to find the different methylation patterns these rearrangements cause, and their knock - on effect on virulence.
Mutational signatures have now been advanced to include mutational processes that involve rearrangements, and novel cancer biological insights have been gained through studying these in great detail.