Recent genetic association studies identified variants in a locus on chromosome 15 (specifically, in the adjacent genes HERC2 and OCA2) that are major determinants of eye color, but the trait is influenced by interaction among at least ten different genes.
Not exact matches
Of these twelve
genetic regions, six are also associated with IBD, while the six other regions showed little to no
association in a
recent large
study of IBD.
A
recent human
study also indicated a
genetic association of the αCaMKII gene with bipolar disorder, and decreased expression of αCaMKII has been observed in postmortem brains of patients with bipolar disorder.
In a
recent study presenting genome - wide
association metaanalysis, the
genetic background of body fat accumulation and its relation with cardiometabolic traits was investigated (187).
Both pedigree - based and population - based linkage analyses rely on estimating
recent IBD, and evidence of ancient IBD can be used to detect population structure in
genetic association studies.
In addition,
recent genome - wide
association studies have identified several hundred common
genetic variants — inherited changes in the DNA sequence of the human genome — that play a role in an individual's susceptibility to complex human illnesses such as heart disease, mental illnesses, cancer and diabetes.
The presence of 1 or 2 copies of the S variant influences predisposition to anxiety, avoidant behaviors, and interpersonal negative emotionality according to several, but not all,
genetic association studies of adults, 20 while a
recent study of childhood shyness - BI21 found an
association in the opposite direction (ie, with the LL genotype).