Innate Immunity Together with Duration of Antigen Persistence
Regulate Effector T Cell Induction
Not exact matches
In this pathway, dopamine - and an adenosine 3 ′, 5 ′ - monophosphate (cAMP)--
regulated phospho - protein of 32 kilodaltons (DARPP - 32) is phosphorylated or dephosphorylated at three sites, in a pattern predicted to cause a synergistic inhibition of protein phosphatase — 1 and concomitant regulation of its downstream
effector proteins glycogen synthesis kinase — 3 (GSK - 3), cAMP response element — binding protein (CREB), and c - Fos.
Actually, almost all signalling pathways that affect cell growth and proliferation directly
regulate rRNA synthesis, their downstream
effectors converging at the Pol I transcription machinery.
Differential glycosylation of TH1, TH2 and TH - 17
effector cells selectively
regulates susceptibility to cell death.
Cbl - b
regulates antigen - induced TCR down - regulation and IFN - gamma production by
effector CD8 T cells without affecting functional avidity.
Among
effectors, 6 of the 18 defensive - like peptides previously annotated are up -
regulated upon infection (Figure 3): three of five defensin homologs, and nasonin - 1, -2, and -3.
Although dCas9 can tether different
effectors, several dCas9 fusions (e.g., dCas9 - VP64 activator and dCas9 - KRAB repressor) can not be co-introduced with sgRNAs to
regulate two set of genes differently since both fusions will bind to both set of genes directed by both sets of sgRNAs (Fig 1).