Sentences with phrase «regulating protein trafficking»

Not exact matches

Other genes activated by the guide RNA encode mitochondrial proteins that help cells regulate their energy metabolism, and trafficking proteins that are involved in packaging and transporting other proteins.

Then, the research group examined the molecular mechanism behind the impaired synaptic functions and behaviors in ARHGAP33 KO mice and found that ARHGAP33 is localized to the Golgi apparatus to regulate intracellular protein trafficking of the Tropomyosin receptor kinase B (TrkB) receptor, a neurotrophin receptor, to synaptic sites.

The research group showed that a molecule, ARHGAP33 regulates synaptic functions and behaviors via intracellular protein trafficking and that the lack of ARHGAP33 causes neuropsychiatric disorder - related impaired higher brain functions.

The Plasma Membrane - Associated GTPase Rin Interacts with the Dopamine Transporter and Is Required for Protein Kinase C - Regulated Dopamine Transporter Trafficking.

When aSyn was produced at low levels, it made its way to the cell membrane and appeared to regulate chemical trafficking and metabolism of compounds called lipids — what may be normal functions for this protein.

Protease - activated Receptor - 4 Signaling and Trafficking Is Regulated by the Clathrin Adaptor Protein Complex - 2 Independent of β - Arrestins.

Tight junctions, regulated by a molecule called zonulin, as well as by conformational changes in the proteins occludin and claudin, are dynamic intercellular structures that modulate the trafficking or passage of macromolecules from the intestinal lumen to the submucosa and into systemic circulation (Fasano, 2012).