Sentences with phrase «retinal pigment epithelium cell»

Citation: Carr A-J, Vugler AA, Hikita ST, Lawrence JM, Gias C, Chen LL, et al. (2009) Protective Effects of Human iPS - Derived Retinal Pigment Epithelium Cell Transplantation in the Retinal Dystrophic Rat.

Researchers used stem cells to create retinal pigment epithelium cells, which were transplanted into a patient's retina (left) in an area depicted by the black circle.

«Previous studies primarily focused on neurons and the retinal pigment epithelium cells as culprits in degeneration,» said Eroglu, who is also a member of the Duke Institute for Brain Sciences (DIBS).

It aims at evaluating the tolerance to a hESC - derived retinal pigmented epithelium cell transplantation.

Not exact matches

From the embryonic stem cells, the researchers produced a type of tissue called retinal pigment epithelium (RPE).

A layer of cells called the retinal pigment epithelium (RPE) is essential for supporting and nourishing the retina cells that capture light for vision.

The volunteers, ranging in age from 20 to 88, received injections under their retina of a particular type of eye cell, retinal pigment epithelium (RPE) cells, which were derived from hESCs in the lab.

The retinal pigment epithelium (RPE) is a single layer of cells that accomplishes multiple functions, such as providing survival molecules that prevent photoreceptors from dying.

It first targets a protective lining called the retinal pigment epithelium (RPE), which shuttles nutrients to the photoreceptor cells and is vital for their survival.

For example, there have been cases of transplanting retinal pigment epithelium and spine cells from stem cells.

About 10 % of cases are due to a mutation in retinal pigment epithelium 65 (RPE65), a gene that codes for an enzyme that helps retinal cells make rhodopsin.

The middle layer is a one - cell - thick sheet known as the retinal pigment epithelium, or RPE.

These vessels supply oxygen and nutrients to the retinal pigment epithelium and photoreceptor cells and carry away waste products.

However, both Goldberg and Albini agreed there is no evidence that this kind of therapy could have treated the patients» sight problems even if carried out correctly and only sparse evidence that adipose cells can differentiate into retinal pigment epithelium or photoreceptor cells, which play a critical role in macular degeneration.

Cell therapy, as envisaged by the teams of I - Stem, is primarily based on the identification of experimental protocols that can specifically guide differentiation of pluripotent cells to a cell fate, which presents a interest for the replacement of the defective cell population from the patient (the striatal neurons for Huntington's disease, the cells of the retinal pigment epithelium for retinitis pigmentosa, keratinocytes for genodermatoses, etCell therapy, as envisaged by the teams of I - Stem, is primarily based on the identification of experimental protocols that can specifically guide differentiation of pluripotent cells to a cell fate, which presents a interest for the replacement of the defective cell population from the patient (the striatal neurons for Huntington's disease, the cells of the retinal pigment epithelium for retinitis pigmentosa, keratinocytes for genodermatoses, etcell fate, which presents a interest for the replacement of the defective cell population from the patient (the striatal neurons for Huntington's disease, the cells of the retinal pigment epithelium for retinitis pigmentosa, keratinocytes for genodermatoses, etcell population from the patient (the striatal neurons for Huntington's disease, the cells of the retinal pigment epithelium for retinitis pigmentosa, keratinocytes for genodermatoses, etc.).

The retinal neurons rely on their supporting cells, such as retinal pigment epithelium (RPE) cells, to provide them with the fuel to meet their energy needs.

The retinal pigment epithelium (RPE) is a layer of cells next to the retina that are metabolically coupled to the retina's photoreceptor neurons.

Madalena Pereira (Ader, TUD)-- «Cell - based replacement of retinal pigment epithelium in rodent models of retinal degeneration» (2014)

Three - dimensional neuroepithelial culture from human embryonic stem cells and its use for quantitative conversion to retinal pigment epithelium.

Lipofuscin is a cytologic hallmark of aging in metabolically active postmitotic cells including neurons, cardiac muscle cells, and the retinal pigment epithelium (RPE).

Specifically, they turned them into retinal pigment epithelium (RPE) cells.

With age, our eyes accumulate waste in retinal pigment epithelium (RPE), which supports the life and function of photoreceptors (light sensitive cells in the eye); in advanced stages, RPE and photoreceptors die.

A pilot study assessing the safety and feasibility of the transplantation of autologous iPSC - derived retinal pigment epithelium (RPE) cell sheets in patients with exudative (wet - type) age - related macular degeneration was launched in Japan in August 2013.

Behind the photoreceptors is another layer of cells called retinal pigment epithelium (RPE), which support the rods and cones by delivering nutrients from the bloodstream and removing waste that the rods and cones generate.

The treatment could help people who have a fault in a gene called RPE65, which causes problems in the retinal pigment epithelium (RPE), a thin layer of cells that support and nourish photoreceptors.

Diseases of the retina may offer an early test bed for hiPSC - derived cells, in the form of retinal pigmented epithelium, given the relative isolation of the tissue, and the small number of cells required [14].

Accelerated Three - Dimensional Neuroepithelium Formation from Human Embryonic Stem Cells and Its Use for Quantitative Differentiation to Human Retinal Pigment Epithelium.

In many forms of human retinal disease, including age - related macular degeneration (AMD), the underlying pathogenesis resides within the support cells of the retina, the retinal pigment epithelium (RPE).

The retinal pigment epithelium (RPE) is a monolayer of cells, residing at the back of the eye between Bruch's membrane and the retina, which is essential for photoreceptor function and survival.

To further examine the morphology of cells and the localization of protein expression within the retina, immunohistochemical staining of both paraffin and OCT retinal sections was performed with the following antibodies (Table S1): human cone arrestin (for cone photoreceptors), rhodopsin (for rod photoreceptors), RPE65 (for the retinal pigment epithelium, RPE), glial fibrillary acidic protein (GFAP, for astrocytes and Müller cells), glutamine synthetase (for Müller cells) and G0alpha (for ON bipolar cells).

Layers of the retina: RPE, retinal pigment epithelium; PR, photoreceptors; ONL, outer nuclear layer; OPL, outer plexiform layer; INL, inner nuclear layer; IPL, inner plexiform layer; GCL, ganglion cell layer; NFL, nerve fiber layer.