Sentences with phrase «rifampin on»

Impact of Rifabutin or Rifampin on Bedaquiline Safety, Tolerability, and Pharmacokinetics Assessed in a Randomized Clinical Trial with Healthy Adult Volunteers.

Not exact matches

Crystal structures of Mtb RNAP bound to rifampin (left), Mtb RNAP bound to an AAP (center), and Mtb RNAP bound to both rifampin and an AAP (right) show that rifampin and the AAP interact with non-overlapping binding sites on Mtb RNAP and, as a result, can bind simultaneously to Mtb RNAP.

Intensive efforts also have been underway to develop new, non rifampin - related Mtb RNAP inhibitors that function through binding sites on Mtb RNAP that do not overlap the rifampin binding site and that thus can kill rifampin - resistant TB bacteria.