Role of amyloid precursor protein (APP) in brain development and implications for Down syndrome
Not exact matches
IRON overload may accelerate Alzheimer's disease, according to research that also reveals the
role of beta -
amyloid precursor protein (APP), which forms plaques in affected brains.
«What's distinct here is a regulatory
role whereby the prion
protein inhibits production
of amyloid beta peptide from its
precursor protein,» says Millhauser.
One interesting hypothesis by the study authors looks at the
role that thyroid hormone plays in regulating the expression
of a gene called the
amyloid precursor protein (APP), which has a
role in Alzheimer's.
Using blood collected from elderly persons aged up to one hundred and demonstrating no cognitive impairment, the researchers isolated precisely those immune cells whose antibodies are able to identify toxic beta -
amyloid plaques but not the
amyloid precursor protein that is present throughout the human body and that presumably plays an important
role in the growth
of nerve cells.
Understanding the
role of soy constituents, such as daidzein, on AβPP (
amyloid - β
protein precursor) synthesis and metabolism and modulation
of intake during pregnancy and infancy could reduce seizure incidence and prevent neurological damage.»