Sentences with phrase «sfari gene database»

Then they examined its contents with cutting - edge mass spectrometry combined with searches of human gene databases.

«We hope that global gene databases will continue to grow, allowing scientist to share and reuse these types of data, and we will update our model as more ASD risk genes are discovered.»

They also looked at Neanderthals, a Denisovan, six chimpanzees and data from public gene databases.

To find a solution to this, Marcel Martin at Bioinformatics Long - term Support (WABI) at SciLifeLab, in collaboration with the group of Gunilla Karlsson Hedestam at Karolinska Institutet, has developed a practical, computational technique, IgDiscover, that enables rapid production of individualized V gene databases following deep sequencing of expressed antibody repertoires.

has developed a practical, computational technique, IgDiscover, that enables rapid production of individualized V gene databases following deep sequencing of expressed antibody repertoires.

However, being a complex multistep process, cancer cytogenetics are broadened to «cytogenomics,» with complementary resources on: general databases (nucleic acid and protein sequences databases; cartography browsers: GenBank, RefSeq, UCSC, Ensembl, UniProtKB, and Entrez Gene), cancer genomic portals associated with recent international integrated programs, such as TCGA or ICGC, other fusion genes databases, array CGH databases, copy number variation databases, and mutation databases.

The SFARI Gene database curates information into several distinct data modules to provide researchers with the most comprehensive, up - to - date research on the genetic causes of autism.

It also has a gene database and is in the process of cataloguing the global gene pool.

Not exact matches

«Once I did the DNA test it linked me to people in their database with the closest gene pool, and it found my aunt and first cousin!»

«Making it easier for the public to access City government databases will make our local agencies more effective and responsive,» said Gene Russianoff, nycTWG co-chair and senior attorney for the New York Public Interest Research Group.

When looking into mechanisms that might affect the levels of SMN protein in neurons, the researchers scanned a genomic database called the UCSC Genome Browser and identified two genetic sequences that matched the opposite DNA strand of the SMN gene.

Using bioinformatics techniques, Dr Jason Brunt and Dr Andrew Carter, working with Professor Mike Peck and Dr Sandra Stringer, screened this database for other entries that were similar to the predicted proteins that the botulinum toxin gene would produce.

In fact, the MESA researchers had included 46 different variants of the gene in their sequencing database.

Night after night Rienhoff tediously compared his daughter's DNA sequence with reference sequences stored in several major genomic databases — Ensembl, Heidelberg, and the UCSC Genome Bioinformatics gene bank, among others.

These analyses eventually pointed to a previously uncharacterized gene listed in the database — Gm7325.

Importantly, the workflow is highly customisable, allowing users to choose parameters, change tools and run the software on their own genes, without having to use the Ensembl database.

He lamented to a graduate student that he had never heard from Prasher; then a search on a computer database turned up a recent paper by Prasher reporting the cloning of the synthetic GFP gene.

To that end, the US National Center for Biotechnology Information in Bethesda is developing a database, ClinVar, to integrate clinical and genetic data; others, such as DECIPHER, run by the Sanger Institute, handle genetic data such as chromosome rearrangements that can disrupt genes.

To solve this problem, Su, Good and their colleagues at TSRI have integrated biomedical data into Wikidata, a public, editable database where researchers can easily link genes, proteins and more.

Rudolph Tanzi of Massachusetts General Hospital in Boston and Ellen Wijsman of the University of Washington, Seattle, both say that they have checked large databases and have found «no evidence» of an AD gene on chromosome 12.

The full data set, with genes identified, is publicly available from EMBL - EBI's Ensembl database.

In a recent attempt, oncologist Todd Golub of the Dana - Farber Cancer Institute in Boston, Massachusetts, and his colleagues collected gene expression profiles, taken from public databases, from 76 tumors.

You type the DNA sequence of your gene into a database, and then you sit and you wait.

Accomplishing that, the Cornell University professor believes, means going beyond the identification and characterization of rice genes or curating a comparative plant - genome database.

First, the researchers looked at published databases of positively selected brain genes, which have been classified into 22 categories according to their function.

By compiling a database of 110 different prokaryote genomes, Todd J. Treangen and Eduardo P. C. Rocha of the Pasteur Institute in Paris calculated the number of genes that had been acquired through horizontal gene transfer.

Researchers would then have to pore through four or five databases for each one, trying to discern which genes (or the proteins they encode) have features most likely to affect the biology of the disorder — a painstaking task.

Large - scale methods of probing samples, such as DNA sequencing, microarrays, and automated gene - function studies, are filling new databases to the brim.

Suspecting that the other four carried a new Ehrlichia species, the researchers sequenced the bacterial gene in their blood and compared it to a database containing the sequences of known infectious bacteria.

In 2002 a student in Christiano's lab was studying the Human Genome Project database and noticed an unnamed region where Christiano had predicted the human version of the lanceolate gene would reside.

EUMODIC was the first step towards the creation of a database of all mouse gene functions, a vision now being realized by the International Mouse Phenotyping Consortium (IMPC).

Using a computational technique called network diffusion, the team identified networks of genes that are interrelated through their connection to the ASD genes in the databases.

They used another database listing interactions between different proteins, to narrow down the list of genes and account for interactions between them.

«None of these genomic features is really a smoking gun per se, but combining them led to a robust detection of «new» viruses — viruses we did not have in the database, but can identify because they have capsid genes and a viral organization,» he said.

That gene is then compared to a database, revealing the fish's identity.

Researchers from BUSM and the University of Cyprus compared the markers on the surface of the cancer cells to gene expression profile of breast tumors deposited by researchers in international public databases and found that a molecule named IL13RA2 (IL13R alpha2) was abundant in metastatic or late - stage BLBC.

«The database is a precious resource for the research community studying plant - microbe interactions as it is an unbiased way to identify potentially interesting genes involved in interaction with a plant — including many totally novel genes.

The researchers also analyzed an independent database of 536 glioblastoma samples and found the same signature of eight genes in those cases.

After eight weeks, they harvested all the viruses in the mice's feces, and identified the viral genes present by comparing them with a large database of known genes.

The yellow - flag system would consist of a centralized biosafety sequence database that would be annotated as evidence of the function of suspect genes comes to light.

The collaboration is not merely about horizontal searches across patient records; it's also about integrating the next generation of gene and protein tests into the Mayo database.

Scanning a genetic database, the researchers matched the faulty gene's sequence to that of a previously defined family of genes.

A key step in this process is to compare symptoms identified by clinicians, such as neurodevelopmental delay or abnormal growth, with an in - house database of all known genes associated with developmental disorders.

To infer the functional effects of these differences, they ran multiple computational analyses, including comparisons to massive databases of known gene functions and of mice in which genes are artificially deactivated.

Duax and his team obtained their results by combing through a database that contains the sequences of more than 90 million genes.

In his talk, Wieland Huttner, a molecular cell biologist and developmental neurobiologist at the Max Planck Institute of Molecular Cell Biology and Genetics (MPI - CBG) in Dresden, Germany, explained how his team searched databases for proteins and other gene products expressed in the human brain in these earliest phases of development.

Finally, they ran the results through a software program that combed through many gene sequences simultaneously, comparing each one with the sequences of known viruses stored in online databases.

Individual genetic diagnoses associated with broad phenotype characteristics catalogued in known Developmental Disorders Genotype - to - Phenotype database genes.

Next, iCAGES cross-references these variants to databases of known cancer - causing genes, using statistical analyses and machine learning techniques to prioritize the most likely driver genes.

When a group of researchers in the Undiagnosed Disease Network at Baylor College of Medicine realized they were spending days combing through databases searching for information regarding gene variants, they decided to do something about it.