Sentences with phrase «sids cases»

Alyce taps the lunch table and asks, «How many SIDS cases came through here lately?»
A, There is a significant difference in the slopes of binding with age in the 200611 and 2010 data sets combined for all SIDS cases and controls (37 - 90 postconceptional weeks)(P =.002).
Second, in components of the medullary 5 - HT system that contain 5 - HT cell bodies (ie, PGCL, gigantocellularis, and intermediate reticular zone), there was a significant age × diagnosis interaction with decreased receptor binding with increasing age in SIDS cases but no change in controls (Figure 2A).
B, The significant difference between the SIDS cases and controls persists when the analysis is restricted to cases and controls that overlap in age (37 - 64 weeks» postconceptional age)(P =.004).
In this nucleus, 5 - HT1A receptor binding decreases with age in the SIDS cases but does not change with age in the controls.
These findings raise the question as to how reduced 5 - HT and TPH2 levels are related to the increased 5 - HT cell density, 11 morphologic 5 - HT neuronal immaturity, 11 reduced 5 - HT transporter binding relative to 5 - HT cell number, 11 and altered 5 - HT receptor binding9 - 11 in the SIDS cases.
We measured 5 - HT1A receptor binding in 10 medullary nuclei from 35 SIDS cases and 5 controls.
We also report that 5 - HT1A binding alterations correlate among components of the medullary 5 - HT system in the SIDS cases (and controls), substantiating our concept that the medullary 5 - HT system is an interrelated network that modulates respiratory and autonomic functions3 — a concept likewise increasingly supported by animal data.3,23 - 25 We now postulate that SIDS can be viewed as a disorder caused by a defect in 1 or more components of the medullary 5 - HT system and that any single case need not express defects in all 5 - HT markers simultaneously.
There were significant alterations in SIDS cases compared with controls occurring in 2 patterns (Table 3).
«Similar to infant SIDS cases, adults often have an impaired ability to wake up after a seizure, especially a general seizure,» Tao said.
In previous studies, the researchers reported multiple serotonin - related brain abnormalities in SIDS cases, including a decrease in serotonin in regions involved in breathing, heart rate patterns, blood pressure, temperature regulation, and arousal during sleep.
Taken together, the researchers wrote, the findings suggest that an abnormality in serotonin metabolism could indicate an underlying vulnerability that increases SIDS risk and that testing blood samples for serotonin could distinguish certain SIDS cases from other infant deaths.
The finding raises the possibility that a test could be developed to distinguish SIDS cases from other causes of sleep - related, unexpected infant death.
In the study, whole - exome sequencing and a targeted analysis of 90 genes implicated in heart disease were applied to 419 unrelated SIDS cases.
In previous studies, the researchers reported multiple serotonin - related brain abnormalities in SIDS cases, including a decrease in serotonin in regions involved in breathing, heart rate patterns, blood pressure, temperature regulation, and arousal during sleep.
Venneman and colleagues5 recently demonstrated that infants who are formula fed are twice as likely to die of SIDS than breastfed infants based on a case control study of 333 SIDS cases compared to 998 aged matched controls in Germany, from 1998 - 2001, consistent with previously published reports.35 While no studies show that co-sleeping in the form of bedsharing, specifically, is imperative for breastfeeding enhancement, many studies have shown that in order to get more sleep and to ease caring for their infants the decision to breastfeed often leads mothers to adopt routine bedsharing for at least part of the night36 - 40 even where they never intended to do so.41, 42 Indeed, nearly 50 % of breastfeeding mothers in the United States and Great Britain adopt bedsharing for some part of the night,38,43 - 45 and breastfeeding women are twice as likely to sleep with their babies in the first month relative to mothers electing to bottle - feed.39
It has been estimated that 5 % to 10 % of infants who die from SIDS have novel mutations in the cardiac sodium or potassium channel genes that result in long QT syndrome as well as in other genes that regulate channel function.44 A recent report described important new molecular and functional evidence that implicates specific SCN5A (sodium channel gene) β subunits in SIDS pathogenesis.47 The identification of polymorphisms in genes pertinent to the embryologic origin of the autonomic nervous system in SIDS cases also lends support to the hypothesis that a genetic predisposition contributes to the etiology of SIDS.
Taken together, the researchers wrote, the findings suggest that an abnormality in serotonin metabolism could indicate an underlying vulnerability that increases SIDS risk and that testing blood samples for serotonin could distinguish certain SIDS cases from other infant deaths.
A retrospective series of SIDS cases indicated that mean maternal body weight was higher for bed - sharing mothers than for non — bed - sharing mothers.172 The only case - control study to investigate the relationship between maternal body weight and bed - sharing did not find an increased risk of bed - sharing with increased maternal weight.173
However, such soft bedding can increase the potential of suffocation and rebreathing.54, 56,57,179, — , 181 Pillows, quilts, comforters, sheepskins, and other soft surfaces are hazardous when placed under the infant62, 147,182, — , 187 or left loose in the infant's sleep area62, 65,184,185,188, — , 191 and can increase SIDS risk up to fivefold independent of sleep position.62, 147 Several reports have also described that in many SIDS cases, the heads of the infants, including some infants who slept supine, were covered by loose bedding.65, 186,187,191 It should be noted that the risk of SIDS increases 21-fold when the infant is placed prone with soft bedding.62 In addition, soft and loose bedding have both been associated with accidental suffocation deaths.149 The CPSC has reported that the majority of sleep - related infant deaths in its database are attributable to suffocation involving pillows, quilts, and extra bedding.192, 193 The AAP recommends that infants sleep on a firm surface without any soft or loose bedding.
A larger but non — peer - reviewed report of hearing screening data in Michigan revealed no relationship between hearing screening test results and SIDS cases.346 Until additional data are available, hearing screening should not be considered as a valid screening tool for determining which infants might be at subsequent risk of SIDS.
Not all of these deaths were SIDS cases; some were cases of accidental smothering or the baby becoming trapped between the mattress and the wall.
About 90 percent of SIDS cases occur during the first six months.
90 % of SIDS cases occur in infants under 6 months of age.
Researchers looked at 1,472 SIDS cases and 4,679 infant controls from five published data sets from the U.K., Europe, Australia and Asia.
«While many theories are flying around about the cause of SIDS, most focus on the deepness of sleep and how it affects the child's breathing... Another theory which you may not be familiar with is that the crib mattress itself is to blame for SIDS cases... Arsenic, phosphorus and antimony are intentionally added to crib mattresses by the manufacturers as fire retardants.
This review of 2,267 SIDS cases and 6,837 control infants explored the duration of breastfeeding required to confer a protective effect against Sudden Infant Death Syndrome (SIDS).
Which is why they were, in the end, looking at very small numbers of SIDS cases.
By denying parents information on best practices about ways they can reduce risks while bedsharing in addition to encouraging them not to bedshare, the public health community potentially shares responsibility for the continued SIDS cases in bedsharing.
According to Dr. Rachel Moon twenty percent of SIDS cases occur amongst infants being left in daycare centers with many dying on the first day or first week of being left there.
For example, in one study of SIDS cases, the risk of sharing a bed became statistically insignificant after researchers controlled for the effects of recent maternal alcohol consumption, infant duvet use, overcrowding, and parental tiredness (Blair 2006).
And to be clear, that is not including babies that sadly die from suffocation through rolling over or bedding strangulation... that is just the SIDS cases.
Most SIDS cases (59 %) occurred between ages 2 and 5 months.
One question that I read asked if there was a difference between those babies who were breastfed and those who were not in the numbers of SIDS cases and this bacteria.
Overdressing is a factor in SIDS cases, so make sure baby is not kept too warm.
However, this population - based, case - control study was limited by a low participation rate of 50 % among eligible cases and 41 % among eligible controls and a small sample size of 185 SIDS cases.
Most SIDS cases occur in the fall or winter months.
Using a 2 - mm micropunch (Harris Uni-core; EMS, Hatfield, Pennsylvania), tissue was collected from 2 major components of the medullary 5 - HT system, the raphé obscurus and paragigantocellularis lateralis (PGCL), according to the atlas of Paxinos and Huang, 19 and standardized protein samples were obtained for Western blot analysis in each SIDS case and control.20 Twenty - micrometer tissue sections were collected from the remaining blocks in a standardized manner for tissue receptor autoradiography.

Not exact matches

Medical Examiner told me in January that one of the previous cases was SIDS also.
Or that a number of the cases, though originally classified as cosleeping deaths, were later ruled as other causes of death, like SIDS.
While I don't think there are any known cases of sudden infant death syndrome (SIDS) due to swaddling, the thought is still quite scary.
And cases of SIDS or other accidental deaths have often involved factors other than bed - sharing - like an intoxicated parent.
Breast feeding reduces the risk of infection and we know that many cases of SIDS are associated with the baby having some kind of mild infection.
Also, if you consider the epidemic of SIDS as a whole, there were about 4250 cases of actual SIDS between 1990 to 1997.
For instance, as James J. McKenna noted in a 2005 piece from Paediatric Respiratory Reviews, bed - sharing may only be one factor involved in the case of SIDS deaths, and that parents should not be turned away from the possibility of co-sleeping entirely.
A young mother, Wendy, worries about Sudden Infant Death Syndrome, or SIDS, because she has had two cases of it in her extended family.
Death certificates are useful for monitoring trends in SIDS mortality, but the circumstances and events that lead to death are not captured in vital statistics data.16 The Centers for Disease Control and Prevention recently began to pilot a SUID case registry that will provide supplemental surveillance information about the sleep environment at the time of death, infant health history, and the comprehensiveness of the death scene investigation and autopsy.
Of these cases, 45 percent were categorized Sudden Infant Death Syndrome (SIDS), an unexplained death of a baby that doesn't have a known cause even after a complete investigation.
Even if SIDS is minimal with co-sleepers, there is possibility to come to that in case you or your partner:
Researchers looked at a total of four case - control studies that examined the association between swaddling and SIDS.
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