Sentences with phrase «sle risk»

«Understanding the relationships between specific SLE risk genes and different manifestations of the disease should help elucidate the underlying disease mechanisms and pathways,» said Dr Antonio Julià of the Vall d'Hebron Research Institute, Barcelona, Spain.

The team also found that having only one copy of NCF1 was associated with a higher SLE risk, but having three or more NCF1 copies was associated with reduced SLE risk.

Furthermore, NCF2, which encodes another subunit of NOX2, is associated with SLE risk in European Americans.

Not exact matches

Investigators at the Medical University of South Carolina (MUSC) report pre-clinical research showing that a genetic variant encoded in neutrophil cystolic factor 1 (NCF1) is associated with increased risk for autoimmune diseases, including systemic lupus erythematosus (SLE), rheumatoid arthritis, and Sjögren's syndrome, in the January 2017 issue of Nature Genetics.

«Understanding more about the genetic pathways which underlie different manifestations of SLE is an important step towards the goal of improving the management of SLE, and ultimately to offer preventative care to individuals at increased risk of SLE,» he added.

This paper reports that variants of IRF5 can confer risk of SLE.

Alternatives to conventional drug based therapy treatments are becoming increasingly popular due to the inability to find a cure for SLE, along with a growing desire for a treatment plan which carries a lower risk of adverse side effects.

We have a history of heart conditions in the family, clearly, and I myself (thanks to genetic hypertension and SLE) am also in the high risk group, apparently.

Some breeds of dogs like Collies, Shetland Sheepdogs, German Shepherds, Afghan Hounds, Beagles, Poodles, and Irish Setters are more at risk of SLE.