Sentences with phrase «sma research»
Today, the SMA Foundation is the leading funder of SMA research worldwide — over $ 110M has been spent on basic, translational, and clinical research.
http://www.smafoundation.org/
While it is unlikely that the SMA Treatment Acceleration Act of 2009 will pass in the coming weeks, we believe that this is a time to celebrate the remarkable efforts of the entire SMA community in driving forward the Federal Government's interest in SMA research.
The funding will enable the institution to significantly expand its already substantial SMA research.
Other SMA investigators have recognized Dr. Monani's achievement — his mouse models are now among the most widely used in SMA research.
«This a remarkable time in the field of neuroscience and SMA research,» said Dr. Fischbach.
SMA research has come far with limited funding and attention.
Since its inception, the Foundation has awarded over $ 100 million for SMA research.
For a complete listing of SMA research articles, please visit PubMed.
This limited supply of EIA kits for the SMA research community is subsidized by the SMA Foundation to expedite evaluation of the kit for use in therapeutics.
The Registry has helped recruit participants for clinical trials and has provided data for important SMA research studies.
Development and distribution of this system could not happen without the successful collaboration with Enzo and contributions from the SMA research community,» said Karen Chen, Ph.D., the Chief Scientific Officer of the SMA Foundation.
In addition, the Foundation is committed to raising awareness, education and increased federal funding and support for SMA research broadly.
Interested parties are invited to contact the Foundation directly at www.smafoundation.org for more information about this and other licensing opportunities for SMA research.
Contingent upon enactment of the FY 2017 Defense spending bill, likely late this year, SMA research projects will be eligible for consideration next year by DOD's Office of Congressionally Directed Medical Research Programs, which has supported over $ 9.7 billion in innovative medical research over the past 25 years.
The Registry has helped recruit participants and provide data for clinical trials and other important SMA research studies.
SMA research and therapeutics development may be applicable to other neurodegenerative diseases, such as amyotrophic lateral sclerosis (also known as Lou Gehrig's disease) and Alzheimer's disease, and may have military relevance.
Not exact matches
Left: Nestle's SMA professional know - how website, promoting SMA HA (see: Nestle launches new hypoallergenic formula promotion campaign as BMJ finally retracts fraudulent research that built the market).
Various health workers have contacted us about a curious market research exercise being conducted by the Millward Brown market research company into a Nestlé SMA advertising campaign.
In addition, the SMA supports research on this disorder by connecting with research institutions, provides information and support to professionals through professional trainings and an active listserv, and provides connection and information to families via social media, online resources, and expert chats.
Consistent with current research, SMA believes that Selective Mutism is best understood as a childhood social communication anxiety disorder.
He is a Research Advisor to SMA and a former Board Member of SMA.
Campaigners argue there are practical difficulties to obtaining consent, potentially impeding research into fatal diseases such as Tay Sachs and Spinal Muscular Atrophy (SMA).
Now, the research team discovered that the disruption of the cellular proteins pICln and Tgs1, two chief players that help assemble the splicing machinery, causes the fruit flies» neuromuscular system to collapse in a similar manner to patients with SMA.
His research found that the earlier the treatment can be administered in mice with SMA, the better the outcome.
The study took advantage of an important large animal model of SMA, the SMA piglet developed by the research group.
«Restoring mitochondrial function might be a new treatment strategy for SMA,» said Yongchao Ma, PhD, senior author and Ann Marie and Francis Klocke, MD Research Scholar, Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago.
Kim's MIT co-authors are first author and graduate student Yunjo Kim; graduate students Samuel Cruz, Babatunde Alawonde, Chris Heidelberger, Yi Song, and Kuan Qiao; postdocs Kyusang Lee, Shinhyun Choi, and Wei Kong; visiting research scholar Chanyeol Choi; Merton C. Flemings - SMA Professor of Materials Science and Engineering Eugene Fitzgerald; professor of electrical engineering and computer science Jing Kong; and assistant professor of mechanical engineering Alexie Kolpak; along with Jared Johnson and Jinwoo Hwang from Ohio State University, and Ibraheem Almansouri of Masdar Institute of Science and Technology.
These results provide us with valuable insight into determining which children with SMA can achieve increases in Hammersmith scores that best correlate with increases in muscle function,» said C. Frank Bennett, Ph.D., senior vice president of research.
Our research centers upon the proteins affected in tuberous sclerosis complex (TSC) and spinal muscular atrophy (SMA)-- two neurological disorders whose genetic basis is well understood but whose cell biology remains unknown.
Our second major line of research aims to understand axonal pathology in SMA, an autosomal recessive neuromuscular disease.
«Targeting the splicing process is a promising strategy for finding new medicines to treat SMA, and possibly other diseases,» said Marcus Rhoades, Ph.D. of the National Institute of General Medical Sciences, which partially supported Krainer's research.
New York, NY — November 29, 2004 — The Spinal Muscular Atrophy Foundation, a nonprofit organization dedicated to finding a treatment or cure for spinal muscular atrophy (SMA)-- the leading genetic killer of infants and toddlers — announced that is has funded more than $ 15 million in research in the last 18 months.
The Woodlands, Texas — May 11, 2006 — Lexicon Genetics Incorporated (Nasdaq: LEXG) announced today that it was awarded a grant from the United States Army Medical Research & Materiel Command (USAMRMC) for the identification of targets that may be important in the development of drugs to prevent or treat spinal muscular atrophy (SMA), a neurodegenerative disorder and the leading genetic cause of death in early childhood.
High throughput screening in motor neurons is a new approach to identifying effective therapy for SMA, said Lee L. Rubin, PhD, Senior Vice President for Research and Development and Chief Scientific Officer for Curis, Inc., and former Professor of Anatomy and Developmental Biology and Director of the Eisai Institute at University College in London.
Complementing its extensive capabilities, PsychoGenics offers a variety of validated mouse models including in - licensed transgenic models that support research in areas such as Alzheimer's disease, Huntington's disease, Parkinson's disease, Autism spectrum disorders, psychosis / schizophrenia, Spinal Muscular Atrophy (SMA), muscular dystrophy and other muscle disorders.
New York, NY — April 19, 2004 — The Spinal Muscular Atrophy Foundation today announced that it has awarded new research grants totaling $ 1.125 million to four outstanding Young Investigators specializing in research on Spinal Muscular Atrophy (SMA), the leading genetic killer of infants and toddlers.
SOUTH PLAINFIELD, NJ — December 6, 2007 — PTC Therapeutics, Inc. (PTC), a biopharmaceutical company focused on the discovery, development, and commercialization of small - molecule drugs targeting post-transcriptional control mechanisms, today announced an expanded research collaboration with the Spinal Muscular Atrophy (SMA) Foundation.
SMA seems so ripe for effective treatment that NINDS has developed a model translational research program to accelerate therapy (www.smaproject.org).
The Columbia University SMA Clinical Research Center is conducting an 18 month trial of the effects of cardiovascular and strengthening exercise on individuals with SMA Type III.
«We see real promise in therapeutic strategies for SMA that increase production of the SMN protein,» said Muscular Dystrophy Association Executive Vice President Research and Medical Director Valerie Cwik, M.D. «We're delighted ISIS Pharmaceuticals is moving forward with a Phase 1 dose - escalation study of its antisense drug in children with SMA.»
PsychoGenics works with pharmaceutical and biotechnology companies, academic institutions and not - for - profit research foundations to address such major neurological disorders as: ALS, Huntington's Disease, anxiety, cognitive impairment, depression, psychosis / schizophrenia and SMA.
Neurology Today: SMA Drug Development Gains Momentum Under NINDS Model for Neuro - Research Partnerships.
About the SMA Foundation Founded in 2003, the Spinal Muscular Atrophy Foundation is a nonprofit organization dedicated to accelerating progress towards a treatment for Spinal Muscular Atrophy through targeted funding of clinical research and novel drug development efforts.
SMA experts and investigators discussed the importance of collaborating with other nonprofit research and patient advocacy groups; targeted genetics research; and new clinical approaches in the pipeline.
Tarrytown, New York and the Spinal Muscular Atrophy (SMA) Foundation New York, NY — have extended their research agreement to establish and behaviorally phenotype transgenic in vivo models of SMA and test potential therapeutics using these models.
The Foundation is also committed to raising awareness and generating support for increased research efforts in SMA among the leaders of industry and government.
Through regional networks in the U.S. like the Pediatric Neuromuscular Clinical Research (PNCR) Network and Project Cure, and international organizations such as the International Coordinating Committee (ICC) and TREAT - NMD, the SMA community has collaborated effectively on recruiting patients, establishing standards of care, standardizing outcome measures, and supporting multi-site clinical efforts, such as the Biomarkers for SMA (BforSMA) and the PNCR Network Natural History studies.
Founded in 2003 to accelerate the development of a treatment for SMA, which afflicts over 25,000 people in the U.S. and has no known treatment, the SMA Foundation works with leaders in research, industry and government to raise awareness, support and research investment.
«We are pleased to bring results from the research sector out for general use in the community,» states Loren Eng, president of the SMA Foundation.
The compounds in PTC's research treat the underlying cause of the disorder and demonstrate increases in SMN levels in nervous system, muscles and other tissues in SMA models.