Sentences with phrase «snf chromatin»
a. Mechanism - guided therapeutic strategies for genetic alterations that affect the SWI / SNF chromatin remodeling complex in epithelial ovarian cancer (such as ARID1A mutation in clear cell and endometrioid subtypes of ovarian cancer, and CARM1 amplification / overexpression in high - grade serous ovarian cancer).
https://wistar.org/
Kapoor P, Bao Y, Xiao J, Luo J, Shen J, Persinger J, Peng G, Ranish J, Bartholomew B, Shen X. (2015) Regulation of Mec1 kinase activity by the SWI / SNF chromatin remodeling complex.
The study published in Molecular Cell is entitled, «The Short Isoform of BRD4 Promotes HIV - 1 Latency by Engaging Repressive SWI / SNF Chromatin Remodeling Complexes.»
The SMARCA4 encodes a catalytic ATPase subunit of the SWI / SNF chromatin remodeling complex.
That gene encodes a protein called BAF 180, which is a subunit of the PBAF subtype of the SWI / SNF chromatin remodeling complex.
Not exact matches
The collection of proteins, called a chromatin remodeling complex, is known as SWI / SNF; its components are encoded by different genes, among them ARID2, PBRM1, and BRD7.
In the first study, Kapoor and collaborators from the laboratories of Drs. Guang Peng, Blaine Bartholomew and Jeff Ranish found that SWI / SNF, known to be important for remodeling chromatin, is also important for activating the DNA damage response.
The bromodomain containing protein 9 (BRD9) has been reported as a component of the switch / sucrose non-fermentable (SWI / SNF) brahma - related gene 1 - associated factor (BAF) complex, which plays a key role in chromatin remodelling and transcription control [1] although the precise biological role is unknown.