Sentences with phrase «snp haplotypes»
SNP haplotypes spanning 3 genes were consistent with autosomal recessive transmission, and microsatellite data showed that only the segment encompassing COLQ was inherited IBD.
http://journals.plos.org/
SNP haplotypes on both chromosomes 23 and 25 were homozygous in the cases and had frequencies of 0.36 and 0.29, respectively, in the unaffected individuals.
Analysis of a linkage peak on chromosome 13 with a dense set of SNPs (single nucleotide polymorphisms) revealed a four - SNP haplotype spanning the gene encoding FLAP (ALOX5AP) that confers an approximately twofold increased risk of myocardial infarction, or heart attack.
Not exact matches
To study natural selection, the team combed the International Haplotype Map for long stretches of DNA flanked by a single nucleotide polymorphism (SNP, or «snip»)-- that is, an altered base, or «letter,» in the genetic alphabet.
We report that a synonymous SNP in the Multidrug Resistance 1 (MDR1) gene, part of a haplotype previously linked to altered function of the MDR1 gene product P - glycoprotein (P - gp), nonetheless results in P - gp with altered drug and inhibitor interactions.
We performed next - generation sequencing to characterize the mtDNAs in the subjects with regard to haplotype, SNPs, and heteroplasmy.
The genetic markers on high - density SNP arrays are carefully chosen to capture (or «tag») most common haplotypes in human populations.
His group developed sample and data tracking systems, automated sequence - assembly tools for the Human Genome Project and sequence variation analysis methods for the SNP Consortium Project and the International Haplotype Map Project.
Haplotype dimorphism in a SNP collection from Drosophila melanogaster K. Teeter, M. Naeemuddin, R. Gasperini, E. Zimmerman, K.P. White, R. Hoskins and G. Gibson J. Expt.
196/2: 30 Haplotypes of common SNPs explain a large fraction of the missing heritability of complex traits.
Haplotype analyses were conducted using PHASE software for SNPs from the 1b receptor gene, TPH1 and TPH2.