Sentences with phrase «sry mutations»

Together, we related how biophysical and biochemical properties affected by the SRY mutation relate to the regulation of a gene - regulatory network in a biological system.»

Not exact matches

Weiss has led a team of scientists through the discovery of multiple unique aspects of the SRY protein mutations, each with its own signature of defects in structure and function.

Mutations in SRY alter the dynamics of male development during fetal life.

Mutations in the SRY protein take place within an L - shaped protein architecture known as a high mobility group (HMG) box.

Mutations in SRY have previously been found that impair the protein's ability to attach to DNA and activate specific genes involved in sex determination.

The new analysis is unusual in that the toddler's SRY, containing a mutation on the back surface of the protein, binds and bends DNA normally.

The toddler in the study had a mutation in the gene encoding SRY, or sex - determining region of the Y chromosome, a protein that initiates testes development in embryos.

Surprisingly, no one seems to have studied this family or their interesting mutation from a biophysical perspective or toward the goal of how the mutation might affect the gene - regulatory properties of SRY.»