Sentences with phrase «stap cells»

What makes Dr. Obokata's newly discovered cells, called «Stimulus - Triggered Acquisition of Pluripotency,» or STAP cells, so remarkable is that they are created, not by genetic manipulation, but through exposure to a more acidic environment.

The stem cell research community hopes that as more is understood about STAP cells, they will join embryonic stem and iPS cells as another reprogramming tool for use in their collective quest to understand and treat human disease.

Called STAP cells, the new stem cells can change into more types of cells than other lab - made stem cells.

In comparison with his first revised protocol in March («Refined protocol for generating STAP cells from mature somatic cells»), the new one («REVISED STAP CELL PROTOCOL.

«We found that while pH alone resulted in the generation of STAP cells, the use of a low pH solution containing ATP, dramatically increased the efficacy of this conversion.

«In recent months, our lab decided to re-explore the utility of a low pH solution containing ATP in generating STAP cells,» Vacanti writes in the revised protocol.

«I don't really hear from almost anyone who fully believes in STAP cells anymore,» wrote stem cell researcher Paul Knoepfler of the University of California, Davis, School of Medicine wrote in a 25 March blog post.

In the latest twist in the story of STAP cells, a new kind of stem cell described in two Nature papers in January, a scientist is live - blogging his latest attempt to generate the cells.

In his most recent online poll, 53 % of respondents indicated that they were «convinced» or «close to convinced that [STAP cells] are not real.»

In December, investigators finally concluded that the so - called STAP cells had

On 5 March, RIKEN released more detailed procedures for the creation of the STAP cells.

Separately, Kenneth Ka - Ho Lee, an embryologist and stem cell researcher at the Chinese University of Hong Kong who live - blogged about his futile attempts to reproduce STAP cells, today published all the details of his efforts online at F1000Research.

And as the scrutiny has grown, several of the collaborating researchers have confirmed that they have not yet produced STAP cells either.

Among the authors, only Charles Vacanti, an anesthesiologist and tissue engineering specialist based at Brigham and Women's Hospital in Boston, says his lab can make STAP cells.

«The mission of the investigating committee is to determine whether or not there has been misconduct; whether STAP cells exist is something for the scientific community to determine,» said committee chair Shunsuke Ishii, a RIKEN molecular geneticist, at the press conference, which lasted a marathon 4 hours.

He added that to the best of their knowledge, no outside group has reported success in generating STAP cells.

Experiments to clarify whether or not STAP cells do exist continue at Harvard and Riken.

More cautious researchers would have realized they were on the wrong track, says Rudolf Jaenisch, a stem cell researcher at the Massachusetts Institute of Technology in Cambridge whose lab spent 2 months trying to make STAP cells and contributed data to the new paper.

Controversy continues to swirl around two recent papers reporting that simply stressing adult cells could turn them into powerful stem cells called STAP cells.

Scientist Kenneth Ka - Ho Lee, who has been trying to reproduce STAP cells and has been regularly blogging about his progress, has given up, writing «I don't think STAP cells exist and it will be a waste of manpower and research funding to carry on with this experiment any further.»

«It would be naive to think that only the letter [the second paper] can be retracted and that the [methods] article will remain with the STAP cell narrative overall having any legitimacy,» stem cell researcher Paul Knoepfler of the University of California, Davis told ScienceInsider in an e-mail.

[W] e believe the committee has nevertheless carried out its investigation appropriately and have concluded that the allegations do not affect the committee's findings concerning the STAP cell papers,» Noyori said, adding that the allegations would be investigated separately.

«At this stage, considering the STAP cell discovery itself to be fabricated is a misunderstanding; I can not possibly accept this,» she wrote.

Yamanaka was not involved in the STAP cell research.

Vacanti said that he was confident that Niwa would «replicate the core STAP cell concept that my brother Martin and I originally hypothesized, and trust that it will be verified by the RIKEN as well as independently by others.»

Not exact matches

«And as the scrutiny has grown, several of the collaborating researchers have confirmed that they have not yet produced STAP [stimulus - triggered acquisition of pluripotency] cells either.»

She «is willing to retract a paper concluding that so - called STAP stem cells can form a wide variety of tissues, but does not intend to retract the paper describing how to make those stem cells.»

► In April, we reported that stem cell scientist Haruko Obokata (the lead author of the two STAP — stimulus - triggered acquisition of pluripotency — papers in Nature) was found guilty of research misconduct by a RIKEN investigating committee.

► On Wednesday at ScienceInsider, Dennis Normile reported that stem cell scientist Haruko Obokata (lead author of the two STAP — stimulus - triggered acquisition of pluripotency — papers in Nature) «has agreed to retract the two Nature papers that reported her work.»

► This afternoon, Normile reported at ScienceInsider that top administrator's at RIKEN, Japan's network of laboratories, «will voluntarily return 1 to 3 months of their salaries to atone for their responsibility for the STAP stem cell fiasco.»

► You may remember «last year's sensational claims surrounding stimulus - triggered acquisition of pluripotency (STAP) cells, the supposedly powerful stem cells derived using a remarkably simple recipe,» as Gretchen Vogel described it in a piece published Wednesday.

Sasai was a co-author on two research papers that claimed to produce embryonic stem cells called STAP from adult cells using acid.

The 30 - year - old was widely celebrated when she and colleagues published two papers in Nature describing a new and surprisingly simple way of creating stem cells, which the researchers dubbed stimulus - triggered acquisition of pluripotency (STAP) cells.

RIKEN launched an investigation after claims of image manipulation and plagiarism surfaced regarding a research article and a letter published online in Nature on 29 January that described a new, simple way of creating stem cells called STAP, for stimulus - triggered acquisition of pluripotency.

► Last Friday, Dennis Normile reported on a bizarre turn in the STAP (stimulus - triggered acquisition of pluripotency) stem cell affair.

Shunsuke Ishii, the chair of the RIKEN investigating committee that recently found stem cell scientist Haruko Obokata (first author on the Nature papers reporting the STAP results) guilty of research misconduct, is himself under investigation for research misconduct.

Furthermore, when the team suppressed STAP - 2, the prostate cancer cells showed reduced proliferation and did not form a tumor when transplanted into mice.

Sasai was co-author on two papers that claimed to produce embryonic stem cells called STAP from adult cells using acid.

The research coming under fire reported the discovery of a potentially revolutionary process called stimulus - triggered acquisition of pluripotency (STAP), in which exposing adult cells to a stress such as acid or pressure prompts them to behave like cells in early embryos, which can become any cell type in the body.

The committee's final report (in Japanese), released today, is the latest blow against a surprisingly simple method for creating stem cells, known as STAP (stimulus - triggered acquisition of pluripotency), published in a Nature article and an accompanying letter online on 29 January by Obokata and colleagues at RIKEN CDB, along with other institutions in Japan and at Harvard Medical School in Boston.

Yamanaka was referring to a recent string of public apologies by stem cell scientists in Japan, triggered by two high - profile papers published earlier this year that claim to have found an alternate way to reprogram adult cells into embryolike ones — called STAP (stimulus - triggered acquisition of pluripotency) cells.

STAP, or stimulus - triggered acquisition of pluripotency, is the name given to an extremely easy way of deriving stem cells, which can theoretically develop into any of a body's tissues.

The top administrators of RIKEN, Japan's national network of research laboratories, will voluntarily return 1 to 3 months of their salaries to atone for their responsibility for the STAP stem cell fiasco.

They described what they dubbed stimulus - triggered acquisition of pluripotency (STAP) cells in a research article and a research letter published online in Nature on 29 January.

But lately he had been immersed in controversy over two papers, published in Nature in January, that claimed a simple method of creating embryonic - like cells, called stimulus - triggered acquisition of pluripotency (STAP).

Two papers claiming that stressing the body's cell could produce embryonic - like stem cells, a process called stimulus - triggered acquisition of pluripotency (STAP), were heralded when published in Nature in January but thrashed soon after when problematic images and figures were soon found.

STAP (stimulus - triggered acquisition of pluripotency) cells were thought to be engineered stem cells created when hematopoietic stem cells from the spleens of newborn mice were exposed to an acid environment, triggering their conversion from multipotent somatic cells to pluripotent - like stem cells.

Another Nature stem cell article has been retracted, indicating the STAP retraction legacy is not yet over.