Sentences with phrase «stat3 ubiquitylation»

This is the first time an epigenetic signal has been shown to impact ubiquitylation and connects the patterns of epigenetic information in a new way.

A protein that is inactive in the absence of additional modification (s), such as phosphorylation or ubiquitylation.

c - Cbl mediated ubiquitylation and regulation of cell surface exposure of CD5.

Enhanced ubiquitylation and accelerated degradation of the dopamine transporter mediated by protein kinase C. Journal of Biological Chemistry, 280 (42), 35617 — 35624.

STAT3 Ubiquitylation and Degradation by Mumps Virus Suppress Cytokine and Oncogene Signaling

The latest publication of the Robinson - lab (Lancaster University, UK) in collaboration with the Ettema - lab is now available online at Nature Communications, regarding the «Functional reconstruction of a eukaryotic - like E1 / E2 / (RING) E3 ubiquitylation cascade from an uncultured archaeon» — the first time that the ubiquitination cascade has been demonstrated outside of eukaryotes.

Targeting of HIF - α to the von Hippel - Lindau ubiquitylation complex by O2 - regulated prolyl hydroxylation.

As such, it appears that the insulin / IGF - PI 3K pathway not only regulates myofibrillar cleavage through caspase 3, but also the ubiquitylation of the resulting protein fragments via modification of ubiquitin - ligase expression.

Decreased mTORC1 activation and subsequent decreases in muscle protein synthesis, coupled with increased FOXO nuclear localization, increased transcription of atrophy - related genes, with up - regulated caspase 3 activation and muscle protein ubiquitylation provide a possible mechanism contributing to skeletal muscle loss in response to periods of negative energy balance.