Sentences with phrase «stem cells study from»

Now, a new STEM CELLS study from the labs of Qing - Ling Fu (Sun Yat - sen University, Guangzhou) and Zhongquan Qi (Xiamen University, Fujian, PR China) has described the effect of iPSC - MSCs on immune T cells in a relevant in vivo mouse model.

Interestingly, a previous STEM CELLS study from Janeczek et al. [3] established that activating the WNT signaling «pathway in BM led to the generation of an osteogenically enhanced subset of stem cells.

Not exact matches

In 2010, researchers from the University of Michigan Comprehensive Cancer Center published a study in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cells.

Dr. Liyun Li graduated Phi Beta Kappa from MIT and received her M.D. with honors from Harvard Medical School where she studied stem cell biology and cultivated a keen clinical...

In a group of patients who underwent surgery for epilepsy, over half had stem cells where healthy individuals do not have them, according to a study from Sahlgrenska Academy.

Although liver cells created from induced pluripotent stem cells reflect the defects of their source, they may offer a new tool to study inherited disorders

Speeches came from a variety of speakers, including a science broadcaster and writer, a Pakistani - born Canadian Muslim who works in STEM, a Pakistani - born professor who studies cell biology and anatomy; and, an emergency room physician who helped start the process to phase out coal - fueled power plants by 2030 in Alberta.

According to the study results, YAP is excluded from the nucleus on the soft gels, and its depletion there helps drive the stem cells onto a brain cell developmental pathway.

Now, in a new study published today, Sept. 8, in the Proceedings of the National Academy of Sciences, a team of researchers from the University of Wisconsin - Madison has added a new wrinkle to the cell differentiation equation, showing that the stiffness of the surfaces on which stem cells are grown can exert a profound influence on cell fate.

Adding stem cells from human bone marrow to a broken diabetic bone enhances the repair process, increasing the strength of the newly formed bone, according to a laboratory - based study presented at the European Congress of Endocrinology in Dublin.

For example, animal studies have shown that neurons derived in the lab from human embryonic stem cells improve Parkinson's symptoms; however, any residual stem cells associated with those neurons could form masses of unwanted cells.

The researchers added human bone marrow stem cells from a non-diabetic donor to a bone fracture in laboratory pre-clinical studies.

The authors of the study say that improvements in management, multi-drug chemotherapy, immunotherapies, stem cell transplants, radiotherapy and treatments that have less toxic side - effects have all contributed to the improvement in survival from leukemia.

The current study was designed to clarify the cellular hierarchy underlying glioblastoma, to identify epigenetic factors that distinguish glioblastoma stem cells from more differentiated tumor cells and to suggest potential therapies targeting those factors.

This work stems from a previous study by Varghese's group to understand how calcium phosphate minerals found in bone tissue induce stem cells to differentiate into osteoblasts.

Currently, Deng's laboratory is conducting additional preclinical studies using the human - derived stem cells from Down syndrome patients and mouse models to determine whether cellular and behavioral abnormalities can be improved with minocycline therapy and other candidate drugs.

Pre-clinical studies have shown it to be effective in eliminating a number of different kinds of cancers cells, including cancer stem cells from human breast cancer patient biopsies.

«From the current research atmosphere and infrastructure, the government has judged that stem - cell studies are now maturing,» says Hyung Min Chung, president of Seoul - based biotechnology firm Cha Bio and Diostech and an adviser on the budget plan.

Hwang claimed his stem cells did not result from parthenogenesis, but George Daley, head of the study, showed that the genome of Hwang's cell line has a genetic signature that indicates it sprang from a parthenogenetic embryo.

The Gendered Innovations website offers case studies ranging from sex differences in stem cell characteristics to assistive technologies for aging men and women.

In this study, researchers took cells from patients with blood cancer MDS and turned them into stem cells to study the deletions of human chromosome 7 often associated with this disease.

«It's taken years of trial and error, making educated guesses and taking baby steps to finally produce functioning human muscle from pluripotent stem cells,» said Lingjun Rao, a postdoctoral researcher in Bursac's laboratory and first author of the study.

The teams are currently working on the fabrication of 3D structures from the blend suitable for implantation in patient joints with future studies focusing on understanding the peculiar interactions between the blend and stem cells towards refining the quality of regenerated cartilage.

The pluripotent stem cell - derived muscle fibers develop reservoirs of «satellite - like cells» that are necessary for normal adult muscles to repair damage, while the muscle from the previous study had much fewer of these cells.

A few studies showed that stem cells from bone marrow could create scar tissue.

For this study, Nakano and his collaborators used cancer cells from 40 patients with high - grade gliomas, focusing on tumor cells with a stem - cell signature.

Last week, scientists at Harvard University and Columbia University announced that they had proved the viability of a new way to study a disease — amyotrophic lateral sclerosis — by reprogramming cells from a patient to become pluripotent stem cells, which can then become any type of cell or tissue.

The study was supported by a Science of Human Appearance Career Development Award from the Dermatology Foundation and by grants from the Medical Research Council of the UK, the Empire State Development's Division of Science, Technology and Innovation (NYSTAR), New York Stem Cell Science (NYSTEM), and the Biotechnology and Biological Sciences Research Council in the UK (BBSRC), as well as earlier support from the Steven and Michele Kirsch Foundation.

This study shows that the mesenchymal subtype is the most aggressive subtype, that it has the poorest prognosis among affected patients, and that cancer stem cells isolated from the mesenchymal subtype have significantly higher levels of the enzyme ALDH1A3 compared with the proneural subtype.

To see whether cancer stem cell renewal involves a chain of events similar to that used by embryonic stem cells, and whether the process was affected by oxygen levels, Semenza and graduate student Chuanzhao Zhang focused their studies on two human breast cancer cell lines that responded to low oxygen by ramping up production of the protein ALKBH5, which removes methyl groups from mRNAs.

And it suggests that stem cells derived from embryos should remain the primary reference for iPS cells when researchers want to compare how cells from diseased patients behave, says Nissim Benvenisty of Hebrew University of Jerusalem, who has studied differences between ES cells and iPS cells derived from carriers of fragile X syndrome.

Semenza says previous studies have shown that resistance to chemotherapy arises from the hardy nature of cancer stem cells, which are often found in the centers of tumors, where oxygen levels are quite low.

The disease model, described in a new study by a UC San Francisco - led team, involves taking skin cells from patients with the bone disease, reprogramming them in a lab dish to their embryonic state, and deriving stem cells from them.

Researchers have developed a new way to study bone disorders and bone growth, using stem cells from patients afflicted with a rare, genetic bone disease.

In a new study the PhD students Jan Hoeber, Niclas König and Carl Trolle, working in Dr.Elena Kozlova's research group transplanted human stem cells to an avulsion injury in mice with the aim to restore a functional route for sensory information from peripheral tissues into the spinal cord.

«Investigators create complex kidney structures from human stem cells derived from adults: New technique offers model for studying disease, progress toward cell therapy.»

In the present study, her team took skin cells from patients with lissencephaly and turned them into iPS cells, which they then cultivated under special conditions into neuronal stem cells and neurons that are copies of those in the patients» brains.

They also published findings from an animal study showing that the effect of stem cell therapy following heart attack is indirect — the stem cells themselves do not survive long after being placed in the heart, but they cause enduring effects by stimulating the rapid growth of surviving heart tissue and attracting stem cells already in the heart, which mature into functional heart cells.

The researchers have isolated the sesquiterpene lactone damsin from the plant and studied its effect on cancer stem cells in three different breast cancer cell lines.

Some of the first evidence for cancer stem cells came from studies of leukemia in the 1990s, which showed that only a small subset of the cancerous blood cells could propagate the disease in mice.

«We found that fibrinogen stops adult stem cells from transforming into the mature cells that produce myelin,» explained first author of the study Mark Petersen, MD, a visiting scientist in Akassoglou's laboratory and an assistant adjunct professor of pediatrics at UCSF.

The study developed a new in vitro system made from bone marrow stem cells and studied what would happen if its ambient temperature fell below 37 °C (the natural temperature of the human body).

ONC201 may inhibit cancer stem cell self - renewals by altering their gene expression, according to a study published August 2, 2017 in the open - access journal PLOS ONE by Varun Vijay Prabhu from Oncoceutics, Inc., USA and colleagues.

The studies, led by University College London (UCL) laryngologist Martin Birchall, would take donor larynxes or tracheas from donors, «seed» them with a patient's own stem cells, and then transplant them into the patient.

«Use of induced pluripotent stem cell (iPSC) technology» — which involves taking skin cells from patients and reprogramming them into embryonic - like stem cells capable of turning into other specific cell types relevant for studying a particular disease — «makes it possible to model dementias that affect people later in life,» says senior study author Catherine Verfaillie of KU Leuven.

A study publishing October 1 in Cell Stem Cell reveals why these symptoms arise and tests an investigational drug in mice that could prevent them from developing.

Earlier mouse studies by Li and his collaborators had indicated that the expression of several imprinted genes changes as hematopoietic stem cells embark on their journey from quiescent reserve cells to multi-lineage progenitor cells, which form the many highly specialized cell types that circulate within the blood stream.

Dr Mohamed Elrayess, from ADLQ, said: «In this study we have shown that the impaired ability of fat stem cells to store excess fat was partially due to increased levels of the inflammatory marker interleukin - 6 in the blood.

The study was funded by grants from Federal Ministry of Education and Research, Germany; National Institutes of Health (EY018213, EY001919, EY020846, DK042394, DK088227, and HL052173); Foundation Fighting Blindness; National Institute for Health Research Biomedical Research Centre at Moorfields Eye Hospital; NHS Foundation Trust; UCL Institute of Ophthalmology; Fight For Sight; Moorfields Eye Hospital Special Trustees; and Barbara & Donald Jonas Laboratory of Stem Cells and Regenerative Medicine, Bernard & Shirlee Brown Glaucoma Laboratory, the Joan and Michael Schneeweiss Stem Cell Fund and Research to Prevent Blindness.

In one study, geneticist Joseph Ecker at the Salk Institute in California took various stem cell lines reprogrammed from skin, fat, and other tissues and examined each line's genome for dna methylation, chemical marks that alter how genes are expressed.