The awards, organised by the European
School of Oncology's Cancer World magazine, attracted 145 entries from every corner of the globe.
Not exact matches
The Harvard Business
School Kraft Precision Medicine Accelerator is working with the MMRF and other cancer partners to harness the potential
of master protocols in precision
oncology.
According to Leena Hilakivi - Clarke, professor
of oncology at Georgetown University
School of Medicine, some women who gained more than 33 pounds during pregnancy had a significantly higher risk
of breast cancer than mothers who kept their weight gain between 25 and 32 pounds.
«We're trying to build models that describe how tumors grow and respond to therapy,» said Yankeelov, director
of the Center for Computational
Oncology at The University
of Texas at Austin (UT Austin) and director
of Cancer Imaging Research in the LIVESTRONG Cancer Institutes
of the Dell Medical
School.
«We present an interdisciplinary approach to studying immunotherapy and immune surveillance
of tumors,» said Benjamin Greenbaum, PhD, the senior author, who is affiliated with the departments
of Medicine, Hematology and Medical
Oncology, Pathology, and Oncological Sciences at The Tisch Cancer Institute at the Icahn
School of Medicine at Mount Sinai.
Already, it includes UCR's Jikui Song, an assistant professor
of biochemistry, and Dr. Samar Nahas, an assistant clinical professor
of gynecology and
oncology in the
School of Medicine.
However, the majority
of patients develop treatment - resistant tumors, and only 10 to 15 percent
of these patients survive long term, says Ie - Ming Shih, M.D., Ph.D., the Richard W. TeLinde Distinguished Professor in the department
of Gynecology and Obstetrics, who led the study with Tian - Li Wang, Ph.D., an associate professor
of pathology and
oncology at the Johns Hopkins University
School of Medicine.
The protein puts the immune system's brakes on, keeping its T cells from recognizing and attacking cancer cells, said Dr. Antoni Ribas, the study's principal investigator and a professor
of medicine in the division
of hematology -
oncology at the David Geffen
School of Medicine at UCLA.
«These results suggest that biology is not as deterministic as many scientists think,» says Andrew Feinberg, M.D., M.P.H., the King Fahd Professor
of Medicine,
Oncology, and Molecular Biology and Genetics at the Johns Hopkins University
School of Medicine and director
of the Center for Epigenetics in the Institute for Basic Biomedical Sciences.
«Patients diagnosed with early - stage prostate cancer — and that's the vast majority
of patients with this disease — face many treatment options that are thought to be similarly efficacious,» said Ronald C. Chen, MD, MPH, UNC Lineberger member and associate professor in the UNC
School of Medicine Department
of Radiation
Oncology.
Physician - scientists at University Hospitals (UH) Case Medical Center and Case Western Reserve University
School of Medicine presented their findings and strategies to increase rates on March 13 at the Society
of Surgical
Oncology Cancer Symposium in Phoenix.
«Estimating from various studies that looked at increasing BMI and endometrial cancer risk, a woman with a Body Mass Index (BMI)
of 40 would have approximately eight times greater risk
of endometrial cancer than someone with a BMI
of 25,» said first author Kristy Ward, MD, the senior gynecologic
oncology fellow in the Department
of Reproductive Medicine at UC San Diego
School of Medicine.
Professor Paolo Boffetta (MD), the Annals
of Oncology associate editor for epidemiology and Director
of the Institute
of Translational Epidemiology at the Icahn
School of Medicine at Mount Sinai in New York (USA), commented: «These results are extremely important in showing that reducing cancer mortality can be achieved: priority should be given to research in cancers with unfavourable trends, such as pancreatic cancer, and in reducing cancer mortality disparities, both between countries (Central / Eastern versus Western Europe), and within countries, for example, between socioeconomic groups.
«Our analysis found that the lowest satisfaction scores were obtained from population - dense regions
of Washington, DC; New York State, California, Maryland and New Jersey, and the best scores were from Louisiana, South Dakota, Iowa, Maine and Vermont,» said senior author Randall Holcombe, MD, Professor, Medicine, Hematology and Medical
Oncology, Icahn
School of Medicine at Mount Sinai, and Chief Medical Officer for Cancer for The Mount Sinai Health System.
«Our preclinical data suggest that combining low doses
of these inhibitors will enhance the clinical effects
of both drugs as a potential treatment for patients with AML,» says the senior author, Feyruz V. Rassool, PhD, associate professor
of radiation
oncology at the University
of Maryland
School of Medicine (UM SOM) and a researcher at the University
of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center (UMGCCC).
«Across the country, large hospital size and non-English as a primary language predicted poor patient satisfaction scores while white race and higher education level predicted better scores,» said co-author Daniel McFarland, DO, Clinical Fellow, Hematology and Medical
Oncology, Icahn
School of Medicine at Mount Sinai.
If not, then we probably shouldn't be using it,» says Nita Ahuja, M.D., an associate professor
of surgery and
oncology at the Johns Hopkins University
School of Medicine and leader
of the study published online on Dec. 18 in JAMA Surgery.
«This is not positive news for astronauts deployed on a two - to - three - year round trip to Mars,» said the professor
of radiation
oncology in UCI's
School of Medicine.
Young people with body mass indexes (BMIs) over 30 are more likely to experience aggressive malignancies, says author Nathan A. Berger, MD, Hanna - Payne Professor
of Experimental Medicine; director
of the Center for Science, Health and Society; member
of the Case Comprehensive Cancer Center; and professor
of medicine, biochemistry,
oncology and genetics at Case Western Reserve University
School of Medicine.
«It was kind
of fun being at a medical
school and known as the weird guy who worked with dogs,» says Modiano, who is now a professor
of comparative
oncology at the University
of Minnesota College
of Veterinary Medicine and the Masonic Cancer Center, where his research focuses on immunology, cancer cell biology, cancer genetics, and applications
of gene therapy.
Future studies are planned by Chang and other
School of Medicine researchers — including senior author Kenneth R. Carson, MD, PhD, an assistant professor
of oncology, and Graham Colditz, MD, DrPH, a cancer expert who also is associate director
of prevention and control at Siteman Cancer Center at Washington University
School of Medicine and Barnes - Jewish Hospital.
Often, it is not diagnosed until at a late stage, when many tumors have already formed,» said principal investigator Lucian Chirieac, MD, a thoracic
oncology pathologist in the Department
of Pathology at BWH and associate professor at Harvard Medical
School.
To ensure that patients can receive all recommended care, we need to recognize the financial burden
of cancer and identify patients at risk for financial concerns,» says lead study author Christine M. Veenstra, M.D., M.S.H.P., clinical lecturer in hematology /
oncology at the University
of Michigan Medical
School.
«If you're going to use an MRI scan or a CT scan or... do something like radiosurgery, you need a team
of people, because nobody has the expertise to span neurosurgery, the medical portion
of radiation
oncology, and medical physics,» says Frank Bova, professor
of neurosurgery at the University
of Florida medical
school in Gainesville.
Division
of Biostatistics and Bioinformatics, Department
of Oncology, Sidney Kimmel Cancer Center, Johns Hopkins University
School of Medicine and Department
of Biostatistics, Johns Hopkins Bloomberg
School of Public Health, 550 North Broadway, Baltimore, MD 21205, USA.
«This study opens the door for combination therapy with BRAF inhibitors and autophagy inhibitors, which haven't been explored deeply as a therapeutic option for patients whose tumors are resistant,» said Ravi K. Amaravadi, MD, assistant professor
of Medicine in the division
of Hematology /
Oncology at the Perelman
School of Medicine and co-leader
of the Cancer Therapeutics Program at Penn Medicine's Abramson Cancer Center.
This is the first study to show the role that type I interferon plays in driving the body's immune destruction during HIV infection, said Scott Kitchen, associate professor
of medicine in the division
of hematology /
oncology at the David Geffen
School of Medicine at UCLA and senior author
of the study published in the peer - reviewed Journal
of Clinical Investigation.
Location was another reason for choosing the Translational
Oncology Laboratory at Barts and The London Queen Mary's
School of Medicine and Dentistry.
Stem Cell Program, Division
of Hematology and
Oncology, Pediatric Hematology Program, Boston Children's Hospital and Dana - Farber Cancer Institute, Harvard Medical
School, Boston, MA 02115, USA.
«While tumor profiling holds the promise
of improved therapeutics through personalized medicine, it is important that both clinicians and patients discuss the possibilities
of incidental findings prior to ordering the testing, as the findings can have serious implications for both the patient and their family members,» said Melinda Yushak, M.D., M.P.H., first author on the study and a medical
oncology fellow in Yale
School of Medicine.
Principal investigator Leena Gandhi, MD, PhD, director
of the thoracic medical
oncology program at Perlmutter Cancer Center at NYU Langone Health and associate professor of Medicine in the division of Medical Oncology at NYU School of Medicine, presented these findings April 16 at the American Association for Cancer Research (AACR) Annual Meeting 2018 in
oncology program at Perlmutter Cancer Center at NYU Langone Health and associate professor
of Medicine in the division
of Medical
Oncology at NYU School of Medicine, presented these findings April 16 at the American Association for Cancer Research (AACR) Annual Meeting 2018 in
Oncology at NYU
School of Medicine, presented these findings April 16 at the American Association for Cancer Research (AACR) Annual Meeting 2018 in Chicago.
Naomi Ko, MD, MPH, instructor
of medicine in the Section
of Hematology
Oncology at Boston University
School of Medicine and a practicing breast oncologist at Boston Medical Center, stresses the need for further investigation.
«We wondered whether we could make a safer and more tolerable form
of DON by enhancing its brain penetration and limiting its exposure to the rest
of the body and, thus, toxicity,» says Barbara Slusher, Ph.D., professor
of neurology, medicine, psychiatry, neuroscience and
oncology at the Johns Hopkins University
School of Medicine and director
of Johns Hopkins Drug Discovery.
said UNC Lineberger's Stergios Moschos, MD, an associate professor in the UNC
School of Medicine Department
of Hematology /
Oncology and a co-author
of the study.
Jean - Pierre Issa, MD, Director
of the Fels Institute for Cancer Research and Molecular Biology at Temple University
School of Medicine and co-Leader
of the Cancer Epigenetics Program at the Fox Chase Cancer Center is lead author
of the study, which has been published August 19 in the journal, Lancet
Oncology.
In men whose prostate cancer spreads, doctors typically prescribe drugs that block testosterone production, but cancer cells eventually become resistant to this means
of reducing the hormone, says Denmeade, a professor
of oncology at the Johns Hopkins University
School of Medicine.
The tumors» genomes were then analyzed for genetic mutations, or alterations in their DNA, by her team and that
of Bert Vogelstein, M.D., professor
of oncology at the Johns Hopkins University
School of Medicine and the co-director
of the Ludwig Center at the Johns Hopkins Kimmel Cancer Center.
In addition, the subgroup
of patients with unmethylated MGMT promoter and HLA - A2 appear to particularly benefit,» said Patrick Y. Wen, MD, director
of the Center for Neuro -
Oncology at Dana - Farber Cancer Institute and professor
of Neurology, Harvard Medical
School, who will present the data at the conference.
«For someone to go up against alectinib, it would be nice to know earlier if there might be an improvement,» says Robert C. Doebele, MD, PhD, investigator at the University
of Colorado Cancer Center and associate professor
of Medical
Oncology at the CU
School of Medicine.
Stewart Massad is chief
of the gynecologic
oncology division at the Southern Illinois University
School of Medicine in Springfield.
As
of 1991, Dr. Jain is the Andrew Werk Cook Professor
of Tumor Biology (Radiation
Oncology) at Harvard Medical
School, and director
of the Edwin L. Steele Laboratory
of Tumor Biology at Massachusetts General Hospital.
However, some
of these cancers become resistant to the effects
of radiation over time, according to Venu Raman, Ph.D., an associate professor
of radiology and radiological science and
of oncology at the Johns Hopkins University
School of Medicine and member
of the Johns Hopkins Kimmel Cancer Center.
«We are planning clinical trials with a recently developed vaccine to target annexin A2,» says Zheng, an associate professor
of oncology and surgery at the Johns Hopkins University
School of Medicine.
Co-investigators on the study are Vancheswaran Gopalakrishnan, doctoral student at The University
of Texas Health Science Center at Houston
School of Public Health; Christine Spencer, Tatiana Karpinets, Ph.D., Robert Jenq, M.D., and Andrew Futreal, Ph.D.,
of Genomic Medicine; Miles Cameron Andrews, Ph.D., Alexandre Reuben, Ph.D., Jeffrey Lee, M.D., and Jeffrey Gershenwald, M.D.,
of Surgical
Oncology; Michael Tetzlaff, Ph.D., M.D., and Alexander Lazar, M.D., Ph.D.,
of Pathology; Wen - Jen Hwu, M.D., Ph.D., Claudia Glitza, M.D., Ph.D., Hussein Tawbi, M.D., Ph.D., Sapna Patel, M.D., Michael Davies, M.D., Ph.D., and Patrick Hwu, M.D.,
of Melanoma Medical
Oncology; Padmanee Sharma, M.D., Ph.D.,
of Genitourinary Medical
Oncology and Immunology; and Jim Allison, Ph.D.,
of Immunology.
«The link between metabolism and cancer has been proposed or inferred to exist for a long time, but what is more scarce is evidence for a direct connection — genetic mutations in metabolic enzymes,» said senior author Ricardo C.T. Aguiar, M.D., Ph.D., associate professor
of hematology -
oncology in the
School of Medicine and a faculty scientist with the Cancer Therapy & Research Center (CTRC) at the UT Health Science Center and the South Texas Veterans Health Care System, Audie L. Murphy Division.
Ross is the Roger A. Berg Research Professor
of radiology and professor
of biological chemistry at the U-M Medical
School, while Rehemtulla is the Ruth Tuttle Freeman Research Professor
of Radiation
Oncology.
«Even before the patient completes all
of the MRIs, CT scans and other imaging procedures following diagnosis, we can have a recommendation for which drug and dosage to prescribe,» said Kareem Azab, PhD, an assistant professor
of radiation
oncology at the
School of Medicine and the Siteman Cancer Center member who leads the research.
«This is the first national study to identify specific regions
of the United States where residents may be at an increased risk for poor clinical outcomes — including misdiagnoses and late detection — as a result
of limited access to specialized gynecologic cancer care,» says David Shalowitz, MD, a fellow in the division
of Gynecologic
Oncology at the Perelman
School of Medicine at the University
of Pennsylvania, and lead author on the study.
Teeth and nails are good for measuring radiation because they pick up free radicals (atoms, or ions, with unpaired electrons) created by ionizing radiation and can retain them for long periods
of time, says Harold Swartz, a Dartmouth Medical
School professor
of radiation
oncology and director
of the Dartmouth Biodosimetry Center for Medical Countermeasures against Radiation.
Jain is the Cook Professor
of Radiation
Oncology (Tumor Biology) at Harvard Medical
School.