Sentences with phrase «scientists know genes»

Just because scientists know the gene responsible for a rare disease doesn't mean they know what's going on.

Not exact matches

Yet for decades, scientists have known surprisingly little about what genes are linked with the development of Major Depressive Disorder (MDD).

The advance is based on a technique that allows scientists to narrow in on a specific gene and cut - and - paste bits of DNA to change its function, known as CRISPR - Cas9.

The tool is known as CRISPR - Cas9, and it could eventually allow scientists to home in on a particular, potentially faulty gene and swap it out with another, potentially healthy one.

Dawkins was also well known by the public as a great scientist, though his true talent was in communicating scientific ideas in books such as The Selfish Gene (Oxford University Press) rather than in his actual research.

Before this groundbreaking discovery scientists knew that DNA carried genes which parents passed onto their offspring but didn't know how it worked or what DNA looked like.

However, the impact of the two methylation - regulating enzymes was still seen at 10 to 15 months, when scientists found decreased expression of hundreds of genes — many of which are key tumor suppressor genes such as BMP3, SFRP2 and GATA4 — in the smoke - exposed cells and a five - or - more-fold increase in the signaling of the KRAS oncogene that is known to be mutated in smoking - related lung cancers.

Since many genes are altered in autism, the UB scientists knew a histone modifier might be effective.

Scientists believe that is what happened during a 1999 French gene therapy trial on a group of 10 young children with X-SCID, an immune deficiency disorder known as boy - in - the - bubble syndrome.

Knowing what the master genes are could give scientists targets for new pharmaceuticals to treat brain diseases.

They started with pairs of fat yellow mice known to scientists as agouti mice, so called because they carry a particular gene — the agouti gene — that in addition to making the rodents ravenous and yellow renders them prone to cancer and diabetes.

In the 1990s scientists such as himself, he explains, were too caught up in the promise of gene therapy to realize that they did not know enough about it to warrant human testing.

Scientists would like to know the root causes of evil behavior: Is it a product of our genes or environment?

Although piRNAs have been known about for many years, scientists have until now had very little understanding of exactly how the piRNAs that guide PIWI proteins to jumping genes in the nucleus are produced.

Scientists have known for 20 years that SMN is necessary in every cell of the body, since disrupting the gene in a mouse causes early embryonic death, before muscle or nerve cells form.

Deafness has long been known to run in families, and while genes for about 60 syndromes that have deafness as one of multiple symptoms have been mapped, only last month did scientists locate the first of the estimated 100 genes that can cause hearing loss alone.

While the researchers don't know precisely how the gene influences beak size, the work may help scientists better understand the genetic underpinnings of evolution, she says.

Somehow, scientists know, the genes that control development — generally turned off in adult cells — get turned back on again by the oocyte, enabling the cell to take on the youthful potential of a newly fertilized egg.

And determining treatment strategies will be no less complex: Last summer, for example, a team of scientists linked 124 different genes to resistance to four leukemia drugs.

Other scientists are probing the FOXP2 gene further by studying the protein it produces, known as FOXP2.

Next, together with scientists from the Transfaculty Research Platform, they investigated whether any known schizophrenia risk genes are associated with the hippocampus.

Scientists think that this gene silencing process, known as RNA interference (RNAi), might help the worms adapt to changing conditions.

Scientists knew Apc was involved in stifling tumor formation because most colon cancers find a way to turn the gene off.

The scientists found that mice with a mutant gene known to impair mouth movements necessary for speech in humans aren't coordinated enough to run on a track.

Scientists want to know if the virus could interact with other factors, such as mutated genes, to trigger the disease.

Scientists also know dozens of gene variants that increase people's risk of lupus.

Using a gene from fruit flies, scientists have produced the most resilient and stretchy rubber known.

Like Wray, the scientists estimated the genes» rate of evolution by comparing their DNA sequences in two different species, a technique calibrated to the date when the two species are known to have diverged.

Domestic animals from cows to dogs have undergone similar transformations, yet scientists know relatively little about the genes involved.

On closer inspection, the scientists discovered that the three genes involved in producing miR135 are located in areas of the genome that are known to be associated with risk factors for bipolar mood disorders.

The BRAF gene and the protein it makes are involved in the body's pain response, but scientists didn't know whether the gene also played a role in itch.

Scientists already know how to use a weakened strain of a respiratory virus called adenovirus to transport healthy genes to cells.

The genome - editing technique known as CRISPR allows scientists to clip a specific DNA sequence and replace it with a new one, offering the potential to cure diseases caused by defective genes.

Scientists believe that's what happened during a 1999 French gene therapy trial on a group of 10 infants with X-SCID, an immune deficiency disorder known as boy - in - the - bubble syndrome.

Scientists knew a third gene was involved in species» incompatibility, but researchers had technical difficulties identifying it.

For decades, scientists have known that people with two copies of a gene called apolipoprotein E4 (ApoE4) are much more likely to have Alzheimer's disease at age 65 than the rest of the population.

Among the 70 genes that the team's research revealed are markedly different in the giraffe, the scientists identified genes that are known to regulate both of these functions.

Scientists have known for years that the pattern of genes is different in exhausted T cells than in functional T cells that are fully engaged in fighting disease, but the actual extent of these differences has been uncertain.

The scientists also identified four homeobox genes — the kind involved in the development of body structures — which are known to specify the regions of the spine and legs.

An international team of roughly 300 scientists known as the Enhancing Neuro Imaging Genetics through Meta Analysis (ENIGMA) Network pooled brain scans and genetic data worldwide to pinpoint genes that enhance or break down key brain regions in people from 33 countries.

Scientists already know that the possession of certain immune system genes makes people more likely to develop MS, and it could be that these genes make people prone to autoimmune reactions when faced with microbial molecular mimicry.

The team of medics and scientists at the Wellcome Trust Centre for Mitochondrial Research at Newcastle University, together with international collaborators, have identified mutations in a gene, known as TMEM126B, involved in energy production in patient's muscles.

Scientists have known for a while that phages are able to transduce genes but this was considered a rare event for genes encoding resistance to antibiotics.

In a study led by Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research member Dr. Julian Martinez - Agosto, UCLA scientists have shown that two genes not previously known to be involved with the immune system play a crucial role in how progenitor stem cells are activated to fight infection.

At the time, scientists studying Icelandic horses known for a special gait discovered that they, as well as American Standardbred horses used in harness racing, share a somewhat shortened version of a gene called DMRT3.

Because scientists know Neandertals and modern humans mated with each other, «is it possible that the «modern» DNA these late Neandertal groups picked up included genes for enhanced cognitive abilities?»

Scientists have known for years that the genome is riddled with sequences that control gene activity and is not just made up of genes.

In search of an explanation, the scientists combed through the African elephant genome and found at least 40 copies of genes that code for p53, a protein well known for its cancer - inhibiting properties.

Indiana University scientists have discovered the first known instance of a plant or animal lacking several key genes involved in energy production in cells.

The news has thrilled both patients and scientists, who have been working for decades on the technology to mute misbehaving genes, known as RNA interference, or RNAi.