Sentences with phrase «sequencing efforts in»

Sequencing efforts in the past few years have pushed the number closer to 1,000 (ref.
«This study demonstrates the benefit of broad - based sequencing efforts in personalized oncology.

Not exact matches

Venter, who is one of the first people to sequence the human genome, co-founded the company in effort to discover early genetic markers for a variety of disorders.
But rather than buying up a genetic research outfit, it decided to build its own in the form of the Regeneron Genetics Center (RGC), an ambitious four - year old effort to sequence as many exomes (the protein - encoding part of the genome) as possible, pair them with medical records, and accelerate drug development.
It can be argued that (1) the longer version was written by Luke and the confusion is due to the sequence cup - bread - cup, not found in early liturgies and therefore disliked by early copyists, or (2) what Luke wrote was only the shorter version (cup - bread, as in the Didache); the confusion is due to the efforts of copyists to supply additional materials.
Most importantly, he blocked an Arsenal effort in a chaotic sequence, which even the superhuman De Gea was unlikely to stop.
«We have discovered that the two more destructive pathogens share a pattern of parallel changes in their core metabolic pathways that enables them to exploit more efficiently the nutrient resources available in banana,» said Stergiopoulos, who along with bioinformatician Ti - Cheng Chang, led the effort to sequence and analyze the fungal genomes of eumusae leaf spot and yellow sigatoka, comparing their findings with the previously sequenced black sigatoka genome sequence.
«Intensive DNA sequencing efforts to find the genetic «drivers» of metastasis, which is what kills patients in up to 80 percent of cases, have thus far been disappointing, to say the least,» he said.
To aid in relief efforts and facilitate rapid global research, we have immediately released all sequence data as it is generated.
A consortium of peanut growers, peanut shellers, brokers and food manufacturing groups provided $ 6 million in funding for the genome sequencing effort through The Peanut Foundation.
She has sequenced hundreds of tumor samples from across the island in an effort to understand how it evolves and how that affects the devils» survival rates.
The 15 AACR scientists, who were already in Washington, D.C., to meet with the U.S. Food and Drug Administration on genetic testing for cancer patients, tossed around ideas including expanding NCI's tumor genome - sequencing efforts and getting the government to cover the costs of genomic tumor profiling.
Along the way he led BGI, which moved to Shenzhen in 2007, into some of its most ambitious projects, including an ongoing effort to sequence 10,500 bird genomes.
The genes of 50 top bulls have been sequenced in an effort to understand how genes from temperate cattle have influenced important production traits in the modern Brahman breed.
«In addition to funding rice sequencing, the [Thai] government is about to launch an effort that will move on to functional genomics,» says Apichart Vanavichit, a molecular biologist at Thailand's National Center for Genetic Engineering and Biotechnology in Nakorn Pathom, which is helping to sequence chromosome In addition to funding rice sequencing, the [Thai] government is about to launch an effort that will move on to functional genomics,» says Apichart Vanavichit, a molecular biologist at Thailand's National Center for Genetic Engineering and Biotechnology in Nakorn Pathom, which is helping to sequence chromosome in Nakorn Pathom, which is helping to sequence chromosome 9.
In fact two projects, a public effort and a private venture, had competed to capture the sequence.
Lo was encouraged by the variants because retroviruses are extremely mutable pathogens that change their gene sequences again and again in response to immune system efforts to kill them.
The largest population genome sequencing effort to date is published in Nature.
Rapid advances in genome sequencing have provided promising new techniques to help researchers conserve endangered species, but efforts to resurrect extinct animals raise complex legal, ethical and environmental questions, experts said at a 4 November event at AAAS.
As scientists began to sequence human genes in the 1990s, sorting out the cellular locations of each gene's proteins became a priority, says Mathias Uhlén, a microbiologist at the Royal Institute of Technology in Stockholm, Sweden, and director of the Protein Atlas effort.
To demonstrate the utility of the gorilla Y chromosome sequence they generated, the researchers designed genetic markers that can be used to differentiate the genetic relatedness among male gorillas and thus to aid in conservation genetics efforts targeted at preserving this endangered species.
The barley genome sequence also enabled the identification of regions of the genome that have been vulnerable to genetic bottlenecking during domestication, knowledge that helps to guide breeders to optimize genetic diversity in their crop improvement efforts.
This was a daunting task, as the barley genome is almost twice the size of the human genome and 80 percent of it is composed of highly repetitive sequences, which can not be assigned accurately to specific positions in the genome without considerable extra effort.
Their DNA was the basis of the first effort to compile a complete Neandertal genetic sequence, which was published in 2010.
Last year, SciLifeLab researchers also joined an effort to sequence the genomes of microbes living in the Baltic Sea.
Efforts to put individual genome sequences and accompanying personal health information online in a freely accessible database just got a boost in the United Kingdom.
This effort involves first generating lots of tiny, overlapping bits of DNA that must be assembled in the right order after their nucleotide sequences are determined.
Large - scale genome sequencing efforts, like the Human Microbiome Project, have focused on the community of microorganisms that live in the human gut.
When it is complete in 2008, EarthScope's web of instruments will provide public data for geoscience, not unlike the way the human genome sequencing effort has for biology.
At Weill Cornell, Imielinski is participating in the precision oncology effort, which will sequence tumor DNA to match patients to particular therapies.
«Their performance has been remarkable,» says Richard Gibbs, who heads the public sequencing effort at Baylor College of Medicine in Houston.
In today's Nature Genetics, researchers report that they have produced a so - called optical map of the parasite's 14 chromosomes, an achievement that should aid the ongoing effort to sequence the Plasmodium genome.
In this research effort, scientists conducted DNA sequencing on more than 500 adults and children with DCM and more than 1,100 healthy controls from several ethnically distinct cohorts to learn about the genetic profile of the disease.
Participants are enrolled in MSSNG, an effort funded by Google and the nonprofit group Autism Speaks to analyze sequences from 10,000 people.
Her lab selected and grew the algae for sequencing in a collaborative effort with CIFAR Fellow Adrián Reyes - Prieto, who she first met at the Institute's program meetings.
In the latest sequencing effort, Willerslev and researchers from Denmark, China, and the United States analyzed the genomes of 80 polar bears from Greenland and 10 brown bears from North America and Europe.
Warinner began her graduate studies at Harvard in 2004, just after the sequencing of the human genome was completed and by the time she left in 2010, efforts to survey the human microbiome were in full swing.
As part of a long - standing effort to study the rampant drug - resistant TB in Samara, a region of Russia about 1,000 kilometers southeast of Moscow, researchers collected TB isolates from 2,348 patients and sequenced the entire genomes of 1,000 of them.
One way to conceptualize these systems is to think of the processes involved in driving a car: the novice needs to rely on controlled processing, requiring focused concentration on a sequence of operations that require mental effort and are easily disrupted by any distractions.
Another researcher, Richard A. Finkelstein, said that participation in American Society of Microbiology (ASM) meetings supported his efforts to isolate and sequence toxins that cause cholera, a deadly intestinal disease.
Another attendee was Craig Venter, who led a private effort to sequence the human genome in the late 1990s that competed with a public effort led by Collins.
The sequencing effort was a collaboration among IRRI; BGI in Shenzhen, China; and the Chinese Academy of Agricultural Sciences in Beijing.
One well - accepted effort compares the nucleic acid sequences that code for ribosomal RNA and a few proteins in many different organisms.
If such efforts succeed, says Robert Waterston, a geneticist who heads the genome sequencing center at Washington University in St. Louis, Missouri, the technique «could be the start of something impressive.»
PARIS — Scientists have agreed to collaborate on an eagerly awaited effort to sequence the genome of the mosquito Anopheles gambiae, the main vector for the malaria parasite in sub-Saharan Africa.
In an effort to better understand and help combat the ants, a group of researchers led by Neil Tsutsui at the University of California, Berkeley, sequenced the genome of L. humile.
Richard Gibbs and colleagues at the genome center at Baylor College of Medicine in Houston, Texas, will lead the effort, and a group at Celera Genomics in Rockville, Maryland, will add brute - force sequencing power.
«Understanding how Cas9 is able to locate specific 20 - base - pair target sequences within genomes that are millions to billions of base pairs long may enable improvements to gene targeting and genome editing efforts in bacteria and other types of cells,» says Doudna who holds joint appointments with Berkeley Lab's Physical Biosciences Division and UC Berkeley's Department of Molecular and Cell Biology and Department of Chemistry, and is also an investigator with the Howard Hughes Medical Institute (HHMI).
It has launched projects such as a major effort to develop knock - out mice (ScienceNOW, 7 September 2006) and The Cancer Genome Atlas (Science, 16 December 2005, p. 1751), which, with the cancer institute, is sequencing mutations in human cancers.
Both public and private efforts published a rough draft in 2001 and the full sequence was completed in 2003.
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