Sentences with phrase «several clinical trials of»

He has participated in several clinical trials of various vaccines and published a paper on the safety and effectiveness of the Feline Infections Peritonitis vaccine.

In fact, Morgan, Palinkas, Barrett - Connor, and Winged (1993) articulate this with, «In several clinical trials of interventions designed to lower plasma cholesterol, reductions in coronary heart disease mortality have been offset by an unexplained rise in suicides and other violent deaths» (p. 75).

In several clinical trials of interventions designed to lower plasma cholesterol, reductions in coronary heart disease mortality have been offset by an unexplained rise in suicides and other violent deaths

Several clinical trials of such drugs are now under way.

The research team also found mutations in the PIK3CA gene, which has been well studied in cancer and is already the focus of several clinical trials of targeted therapies.

Conservative iron chelation is currently being tested in several clinical trials of Parkinson's disease, Alzheimer's disease and amyotrophic lateral sclerosis.

The Washington University team is planning several clinical trials of such drugs in sepsis patients in the near future.

Previous research raised the possibility that HDL might not be quite as protective against heart disease as generally believed by cardiologists, especially after several clinical trials of HDL - raising drugs showed little or no effect.

Not exact matches

The startup is in the midst of several clinical trials and completed a 52 - week Phase II clinical trial of an osteoarthritis treatment in July.

«IBM and the FDA will explore the exchange of owner mediated data from several sources, such as Electronic Medical Records, clinical trials, genomic data, and health data from mobile devices, wearables and the «Internet of Things,»» said the company in a press release.

Intarcia has completed several late - stage clinical trials in which it uses the pump to deliver a glucose - controlling drug continuously for months — an idea, that if successful (and approved by the FDA) could significantly help patients with type 2 diabetes, fewer than half of whom maintain the recommended glycemic levels.

«Many investors expected a more lengthy FDA review process of the JCAR015 trial (and potentially other CAR - T programs) and feared that a higher - degree regulatory scrutiny could increase the development risk of CAR T cell,» Leerink Research said in a note co-authored by analysts Michael Schmidt, Ph.D., Jonathan Chang, Ph.D., and Varun Kumar, Ph.D. «While it may take several weeks to reopen all clinical sites of the ROCKET trial, we believe the trial shouldn't be delayed by more than ~ 3 months.»

To achieve this goal, several approaches are envisaged: identifying small populations with severe disease where a medicine's benefit - risk balance could be favorable; making more use of real - world data where appropriate to support clinical trial data; and involving health technology assessment bodies early in development to increase the chance that medicines will be recommended for payment and ultimately covered by national healthcare systems.

She oversees several NIMH funded clinical trials targeting the motivational system to enhance the drive to improve one's quality of life and health outcomes.

There are several randomized controlled clinical trials (RCTs) evaluating the effect of probiotic bacteria on the prevention and treatment of allergic disease.

Although some SIDS experts and policy - makers endorse pacifier use recommendations that are similar to those of the AAP, 272,273 concerns about possible deleterious effects of pacifier use have prevented others from making a recommendation for pacifier use as a risk reduction strategy.274 Although several observational studies275, — , 277 have found a correlation between pacifiers and reduced breastfeeding duration, the results of well - designed randomized clinical trials indicated that pacifiers do not seem to cause shortened breastfeeding duration for term and preterm infants.278, 279 The authors of 1 study reported a small deleterious effect of early pacifier introduction (2 — 5 days after birth) on exclusive breastfeeding at 1 month of age and on overall breastfeeding duration (defined as any breastfeeding), but early pacifier use did not adversely affect exclusive breastfeeding duration.

Several JAK2 inhibitors have already been approved by the FDA or are currently in clinical trials for the treatment of other cancers.

Safety of PS - extracts has been established in several clinical trials.

What physicians tell you if you call yourself «Doctor»: Your uncle has non-Hodgkin's lymphoma, but there are several promising treatments in clinical trials, and I've taken the liberty of signing him up for the one with the greatest chance of success.

The researchers suggest a clinical trial should be carried out to compare which of the two strategies is better in treating infection, but it will require several thousands of patients with hip infections.

Gault transferred to a new research area — Alzheimer's disease — where she is now responsible for several proof - of - concept trials, also known as phase II clinical trials.

Sadoff says clinical tests of spray - dried BCG could begin as soon as late 2008, when his group plans to conduct mid-stage trials of several new forms of the vaccine.

Several vaccines against HSV - 1 tested in clinical trials for the prevention of adult - to - adult transmission have failed, Leib noted, but none have been tested for prevention of adult - to - baby so - called «vertical transmission» of the virus.

Decitabine is approved by the U.S. Food and Drug Administration to treat myelodysplastic syndromes and leukemia, and for use in clinical trials for several types of solid - tumour cancers including colorectal.

Tengion develops human «neotissues and neoorgans» using their Autologous Organ Regeneration Platform, and currently has several ongoing preclinical and clinical trials in the area of bladder and kidney augmentation and blood vessel replacement.

Meanwhile, his research teams are moving several other novel therapies toward clinical trials, each of which has potential for use in the synergistic model of cancer treatment that Black believes will offer the best hope for his patients.

However, several clinical trials are currently underway to assess a type of therapy that inhibits a DNA repair enzyme known as PARP in tumors with HRD,» said Heeke.

Hh antagonists are currently in clinical trials for the treatment of several types of cancer.

Hypothermia affects several different mechanisms of injury and has been shown in several clinical trials to be neuroprotective in newborns; however, it may not help the most severe babies.

«Since several BACE1 inhibitors are currently being evaluated in clinical phase 3 trials for the treatment of Alzheimer's disease, the identification of potential side effects will be of great importance to ensure a positive clinical outcome,» said Dr. Jochen Herms, a Professor of translational brain research at Ludwig - Maximilians - University Munich.

In fact, nearly 50 clinical trials have been conducted using potential γ - secretase inhibitors for Alzheimer's disease or several types of cancer.

Work done so far suggests that the technique — a modified form of IVF — is safe enough to try in clinical trials, the HFEA panel said, as long as several extra experiments are carried out first and children born as a result of the technique are followed up for an extensive period.

WASHINGTON, D.C. — Several prominent members of Congress plan to introduce legislation that would create a clinical trials registry, in which all trials must be listed from inception and results posted as they emerge.

QAs need to have a good understanding of safety and confidentiality laws, and of standard operating procedures and regulations, so they should have several years» professional experience in a clinical trial.

In addition, several pharmaceutical companies are including Neurotrack in clinical trials of experimental Alzheimer's therapies.

But a clinical trial suggests that for most infants, surgery followed by the use of contact lenses for several years — and an eventual lens implant — may be the better solution.

Its effectiveness in several clinical trials led the U.S. Food and Drug Administration to approve preventive use of ARVs in 2012.

As a new generation of gene therapy clinical trials shows promise to cure or halt the progression of several rare diseases, the time has come to explore ways to pay for the cutting edge treatments, a pediatric hematologist - oncologist from Dana - Farber / Boston Children's Cancer and Blood Disorders Center argues in a commentary published by the journal Science.

Several human clinical trials began last fall at test sites including BIDMC, WRAIR, and National Institute of Allergy and Infectious Diseases affiliated clinical trial sites.

Several companies, including Second Sight in Sylmar, California, have developed prosthetic retinas, some of which are currently in clinical trials.

The high quality of the new lines should make them appealing for clinical trials, says Braude, but it could take several years before the cells make their way into humans — if they ever do.

Specifically, the research team found that the experimental drug CX456, part of the AMPAkine class in clinical trials for several neurological conditions, counters for the dampening effect of anesthesia on nerve signaling.

«In recent years we've seen a significant improvement in the length of good - quality life men can hope to live even with the most advanced prostate cancers — thanks to clinical trials giving us several new prostate cancer drugs.

Several of the compounds are currently in clinical trials to treat cancers like leukemia and myeloma.

Several types of immunotherapy for glioblastoma are in late - stage clinical trials.

For example, last month's spending bill that established NCATs requests several reports and outside studies of the center's activities and stipulates that it can not support expensive, late - stage clinical trials of the kind typically done by industry.

However, the safety of the copper complex can be validated through several other clinical trials already underway for different uses, he added.

Several early stage clinical trials using autologous infusions of ZFN - generated CCR5 - modified CD4 + T cells are currently underway (clinicaltrials.gov identifiers NCT00842634, NCT01252641, NCT01044654).

Several changes were made for researchers engaged in clinical trials: TCPS 2 (2014) suggested that data from these trials be made available and provided modified methods of data access in multi-site clinical trials for both Principal and Site Investigators [2].

She coordinated several clinical trials on growth hormone therapy in children with CKD and was coordinator of the ESCAPE trial.