Several human trials testing the effectiveness of these extracts have been conducted in the last several years (124 — 130).
Not exact matches
Agrillo, of the University of Padua in Italy, is finishing up
several years of pitting
humans against fish in
trials of their abilities to compare quantities.
An NIH - backed vaccine is among
several heading for
human trials, but the timeline for large - scale deployment remains murky
GABA and related therapies would have to be tested in
human clinical
trials, a process that could take
several years, the researchers said, noting that many treatments that work in mice do not always translate into effective
human therapies.
Neufeld says he's looking forward to testing NOS - 2 inhibitors in clinical
trials for
human glaucoma, and says that
several pharmaceutical companies said they are interested in developing more specific and effective inhibitory molecules.
Sharpe highlights
several hurdles on the route to a
human equivalent of the drug, such as creating an oral version rather than the injectable form used in the rodent
trials.
Assuming this and
several other related
human trials currently under way are a success, the next step will be making enough of these crucial breast - milk sugars and doing it cheaply.
Tengion develops
human «neotissues and neoorgans» using their Autologous Organ Regeneration Platform, and currently has
several ongoing preclinical and clinical
trials in the area of bladder and kidney augmentation and blood vessel replacement.
The drug still needs
several years of animal testing before a
human trial is conceivable, Cheng says.
They are also reaching out to drug industry partners to investigate the potential of initiating
human trials to test glutamate blockers as PTSD therapeutics, which may take
several years to assemble.
«There are
several vaccines in
human trials right now, but to date, none of them has been shown to protect during pregnancy,» said Michael S. Diamond, MD, PhD, the Herbert S. Gasser Professor of Medicine at Washington University School of Medicine in St. Louis, and the study's co-senior author.
Although
human drug
trials are
several years away, Leinwand has cofounded a company to fund her research.
Several drugs and vaccines have shown promise in nonhuman primates, but none of them have successfully made it through phase I
human trials.
Human trials of oligonucleotides for
several other neurological diseases are underway, including Huntington's disease and amyotrophic lateral sclerosis (ALS), commonly known as Lou Gehrig's disease.
Several human clinical
trials began last fall at test sites including BIDMC, WRAIR, and National Institute of Allergy and Infectious Diseases affiliated clinical
trial sites.
Human clinical
trials with the new therapy could begin within the next
several months, researchers say.
The high quality of the new lines should make them appealing for clinical
trials, says Braude, but it could take
several years before the cells make their way into
humans — if they ever do.
Several sites in the Neonatal Research Network, based at the National Institute of Child Health and
Human Development (NICHD), stopped recruiting new patients to six other ongoing
trials while they reviewed documents.
Clinical
trials for
several vaccines are in various phases, with promising published results in
humans.
There are
several potential neuroprotective drugs, but no definite benefit has been shown in
human trials yet.
Currently, Everon is optimizing
several lead compounds: small molecules and biologics that have already demonstrated a rejuvenation effect in aging animals, as measured by a lowered mouse FI (similar FI has recently been accepted by FDA as a measure of aging in the ongoing Metformin
human trial).
PD01A: Promising Animal Efficacy; Initial
Human Safety and Hints of Disease Modification At the time of our last post on α - synuclein vaccines, AFFiRiS had published
several papers about the AFFITOME immnotherapy discovery platform [8 - 11] and had even begun their first Phase I
trial of PD01A, but had kept nearly silent on many of the most elementary aspects of the vaccine.
In addition to preventive vaccines, such as Gardasil and Cervarix, laboratory research and
several human clinical
trials are focused on the development of therapeutic HPV vaccines.
In Louisiana, the 4 - year - old TCA Cellular Therapy company has
several ongoing FDA - approved clinical
trials on
humans, using patients» own stem cells to treat heart and vascular diseases.
Several human clinical
trials have now shown that stem cells can be transplanted into the eye.
Several clinical
trials, including this one led by Emoryâ $ ™ s Nicole Turgeon, have shown that islets isolated from deceased
human donors can restore normal blood sugar regulation in patients with type 1 diabetes.
The good news is that science never stops - researchers have already been working on better drugs for
several years, with
several candidates moving towards
human trials.
The company is collaborating with
several partners in performing
human trials, such as the University of Utah, University of Pittsburgh and the Cleveland Clinic.
With
several human clinical
trials involving the CRISPR gene - editing process moving forward, the original study resulted in a flurry of criticism from many scientists in the field.
It will also be important to determine the effects of IER in other populations, for example in individuals with more profound metabolic derangements such as those with established T2DM, the evidence for which is relatively sparse.36 Additionally, given that
several rodent and
human IER (50 - 100 % ER on restricted days)
trials have demonstrated metabolic improvements in the absence of overall ER 15, 22, 27, 31, 53,105, one can speculate that IER may have potential applications within non-overweight populations and as a maintenance strategy post-weight-loss.
... Longer - term clinical
trials and careful postmarketing surveillance during the next
several decades are needed to determine whether cholesterol - lowering drugs cause cancer in
humans.
The caveat is there aren't too many
human studies with PQQ yet; most of these are animal studies, but preliminary clinical studies are extremely encouraging, and
several larger clinical
trials are currently either completed waiting publication or are in process.
The single
human weight loss
trial of raspberry ketones often cited by supplement companies is confounded by the inclusion of
several other ingredients including caffeine, synephrine, and capsaicin.
Few clinical
trials have been conducted in
humans, although
several long - term studies are now under way.
Several trials using
human cells have shown it to have protective effects on the skin.
When the defense, powered by an organization called Yes on 8, appealed the 2010 win in the Ninth Circuit, and through further appeals over
several years brought it to the U.S. Supreme Court in July 2012, the plaintiffs narrate the
trials, bringing a
human perspective to the legal frustrations.
And while he's been successful in
several attempts with animals, he considers himself five years away from being ready for
human trials.
Dogs don't generalize well - it takes them
several trials for them to think that ALL
humans suddenly know how to play.
Google's self - driving tech spinoff Waymo is set to make a big push into its
trial programs for its autonomous vehicles: the company has inked a deal to buy «thousands» more minivans from Fiat Chrysler, which it plans to run across
several cities in the US without a
human driver at the wheel.