Sentences with phrase «several markers of»

In a recent speech he laid down several markers of change he wanted to see happen in the Courts system.

Closely monitoring several markers of cell damage (including creatine kinase, lactate dehydrogenase, prostaglandin - E and tumor necrosis factor - alpha) in their sample of 18 male athletes (who used 20 grams of creatine monohydrate per day for five days, mixed with 60 grams of maltodextrine), the researchers found levels of these markers were reduced after the race, compared to 16 control subjects who took only the maltodextrine.

After 12 weeks, they had seen improvements in several markers of brain function (25).

In one set of experiments, when the scientists boosted insulin resistance by giving mice a compound that cuts insulin signaling, they saw increased expression of several markers of aging in beta cells.

The scientists identified several markers of aging beta cells, including one protein called IGF1R that is an important player in cell survival.

«The new method has allowed us to measure several markers of diet and nutrient status at the same time in a large number of people, which we believe is the first time this has been done,» he says.

The research, published in PLOS ONE, found that several markers of insulin resistance were increased following sustained exposure (6 - 8 weeks) to hypoxia at high altitude and that this change was related to increased blood levels of markers of inflammation and oxidative stress.

Not exact matches

In my case, several nurses noted I had classic physiological markers for insufficient glandular tissue plus a history of infertility, but specifically noted that they chose not to tell me.

Upon narrowing the study's focus to the three smallest and least studied U.S. racial groups, Pacific Islander, multiracial, and American Indian adolescents had higher prevalence for using several illicit substances as well as every marker of suicidality compared to non-Hispanic white adolescents.

In that study, the UChicago researchers matched genetic markers of the «input» and «output» neurons of the mammalian neocortex with genes expressed in several bird DVR nuclei.

Researchers from several institutions, including, UCLA, Boston University, Stanford University and the Institute for Aging Research at Hebrew SeniorLife, analyzed blood samples from nearly 10,000 people to find that genetic markers in the gene responsible for keeping telomeres (tips of chromosomes) youthfully longer, did not translate into a younger biologic age as measured by changes in proteins coating the DNA.

These markers do not make any proteins, but they contain the names of 46 scientists on the project and several quotations written out in a secret code.

Several researchers, however, are tracking chemical markers in the blood and in the breath with the goal of creating screening tools that could someday not just find cancer but also indicate how dangerous it is likely to be.

Despite this, the extensive breadth of the new study allowed the researchers to identify several genetic markers underlying the fruit size increases, which is great news for breeders who might want to further increase the apple's girth.

After watching those mice thrive for several months, Lagasse repeated the experiment using fluorescent markers to trace the path of the liver cells.

«Thanks to this innovative approach that connects several layers of information, we were able to identify a urinary marker that can easily detect the presence of a case of diabetes,» said Johan Auwerx.

«By analyzing the blood of children of controls and comparing it to children of bipolar patients, we identified several genes or markers that can explain the increased risk.»

Several studies have used cell - surface markers — proteins found on the outer membranes of tumor cells — to identify glioblastoma stem cells; but the specific markers used have been controversial and can not reflect molecular processes going on within tumor cells.

Researchers at Stanford University School of Medicine have identified several new biological markers to measure the progression of the inherited neurodegenerative disorder Huntington's disease (HD).

The cells are tiny — a few could fit on the head of a pin — so a single biodrone could carry several, enabling it to measure multiple atmospheric markers simultaneously.

These included wakeup glucose levels; levels of the essential minerals calcium, iron, and magnesium; fat and cholesterol levels; kidney and liver enzymes; and several markers for inflammation and tissue damage.

Each of these magnetic markers is designed to target specific sites within biomolecules and thus enables several approaches for the structural analysis of different biomolecules.

In a statement put on the Web this morning, NIH reported that all 64 lines «show characteristics of stem cell morphology» and have undergone several population doublings, and most of them have demonstrated all the protein markers «known to be associated with human embryonic stem cells.»

Kisspeptins circulating in the blood increase dramatically during normal human pregnancy, to several thousand times non-pregnancy levels, which makes them a novel predictive marker for assessing the risk of later complications.

A type of antifungal antibody, called ASCA, is widely used as a diagnostic marker since it is highly elevated in the blood of patients with several chronic diseases including Crohn's.

A section of a head and neck tumor — red and green markers show the proliferation of cancer stem cells — that formed when one of several newly characterized genes, Myh9, was suppressed.

Instead of focusing on just a few pre-defined markers, metabolomics analysis allows for the determination of the study participants» metabolic profile, i.e. the concentrations of several metabolites.

He's identified several families with a strong hereditary pattern of the disease and has begun searching for common genetic markers.

Numerous stem rust resistance (Sr) genes are known and in recent years several of these have been cloned and used to develop so - called «perfect» markers to allow more rapid and accurate breeding.

(6) Moreover, subcutaneous adipose of prematurely - aged transgenic mice exhibited high levels of staining for the senescence marker senescence - associated - β - galactosidase (SAβ - gal) and expressed high levels of several established markers of senescence, including p21, p19, interleukin - 6, (insulin - like growth factor binding protein - 2 (Igfbp2), and Pai - 1; primary BubR1H / H; INK - ATTAC mouse embryonic fibroblasts forced artificially into senescence by oncogenic Ras or serial passage exhibited a subpopulation that was both GFP + and stained positively SAβ - gal.

We therefore used several approaches and different nuclear markers to infer the phylogenetic relationships and to estimate the amount of gene flow between ancient and modern horses.

SapTrap includes a prebuilt donor plasmid library containing several types of fluorescent (EGFP, tagRFP, mCherry) and nonfluorescent (Halo, SNAP) tags, a selectable marker -LRB-

SapTrap includes a prebuilt donor plasmid library containing several types of fluorescent (EGFP, tagRFP, mCherry) and nonfluorescent (Halo, SNAP) tags, a selectable marker (floxed Cbr - unc - 119) for easy screening of the insertion event, and a variety of connector modules (linker sequences between the tag and homology arms).

Several postmortem studies report the presence of inflammatory markers in the brains of depressed or mood - disordered patients.

The researchers followed up to identify markers of aging in these cells, using several mouse models — one with impaired glucose tolerance (a contributor to type 2 diabetes progression) and another that shows markers of rapid aging.

Six Xa genes have been tagged with molecular markers and used to help identify new resistant lines, resulting in the release of resistant varieties in several countries.

Of note, mouse neural stem cells (NSCs) were reprogrammed using only one (Oct4) or two factors (Oct4 and Klf4), due to the endogenously high expression of pluripotent genes, such as Sox2 and c - Myc, as well as several intermediate reprogramming markers [14], [17], [18Of note, mouse neural stem cells (NSCs) were reprogrammed using only one (Oct4) or two factors (Oct4 and Klf4), due to the endogenously high expression of pluripotent genes, such as Sox2 and c - Myc, as well as several intermediate reprogramming markers [14], [17], [18of pluripotent genes, such as Sox2 and c - Myc, as well as several intermediate reprogramming markers [14], [17], [18].

A combination of several germ cell markers will thus be necessary to detect germ cell differentiation from ES cells.

There are currently no disease - modifying treatments that have been shown to slow the progression or delay the onset of HD in humans; however, several compounds have demonstrated promise in animal models of HD.1 Robust and sensitive markers of disease progression are required to assess their efficacy in humans.

With the RNAscope ® duplex assay we demonstrated localization of PD - L1 and several immune markers in lung cancers.

«I've woken up from the sound of my wheels on road markers on several occasions,» says the former applications engineer, a dad who used to endure a 55 - mile commute.

Several of my inflammatory markers were higher than I wanted them to be, meaning I was moving in the wrong direction on the autoimmune spectrum.

A study of young male athletes found that 2 weeks of supplementing with CLA improved several inflammatory markers and reduced inflammation.

I can't say for certain that after undergoing advanced lab studies (LDL particle number and size, markers of inflammation, tests for genetics like homocysteine, MTHFR and clotting, lipoprotein a, fibrinogen, and ferritin levels) that I would have found one or several defects to treat in Felicia's husband, but it is likely.

Specifically, they found that berberine significantly inhibited amyloid beta - stimulated production of several inflammation markers, including interleukin - 6 and monocyte chemotactic protein - 1.

For the study, 10 individuals ran and walked at different speeds on a uniquely designed treadmill; several cameras captured their gait with monitoring reflective markers placed on different parts of the individuals» lower limbs as the treadmill collected data from the applied force.

Surprisingly, the researchers did not find increased levels of Alzheimer's markers when they looked specifically at people with obstructive sleep apnea, a breathing disorder that's a major disruptor of sleep and a risk factor for several other chronic diseases.

Several years ago investigators tracked the biotin status of thirteen pregnant women through the course of their pregnancies, measuring a marker of deficiency in their urine.

Of these, several have reported post-treatment reductions in total cholesterol 12, 53, triglyceride 12, 53 and increases in high density lipoprotein (HDL) cholesterol.20 In studies using normotensive rats, three to six months of IER has been observed to lower blood pressure 16 - 19 and heart rate 16, 17, 19, with the magnitude of the change comparable to CER (40 % ER / day) rats.19 In accordance with these findings areimprovements in aortic endothelium - dependent and heart rate variability (a marker of sympatho - vagal balance) in IER - fed rats.Of these, several have reported post-treatment reductions in total cholesterol 12, 53, triglyceride 12, 53 and increases in high density lipoprotein (HDL) cholesterol.20 In studies using normotensive rats, three to six months of IER has been observed to lower blood pressure 16 - 19 and heart rate 16, 17, 19, with the magnitude of the change comparable to CER (40 % ER / day) rats.19 In accordance with these findings areimprovements in aortic endothelium - dependent and heart rate variability (a marker of sympatho - vagal balance) in IER - fed rats.of IER has been observed to lower blood pressure 16 - 19 and heart rate 16, 17, 19, with the magnitude of the change comparable to CER (40 % ER / day) rats.19 In accordance with these findings areimprovements in aortic endothelium - dependent and heart rate variability (a marker of sympatho - vagal balance) in IER - fed rats.of the change comparable to CER (40 % ER / day) rats.19 In accordance with these findings areimprovements in aortic endothelium - dependent and heart rate variability (a marker of sympatho - vagal balance) in IER - fed rats.of sympatho - vagal balance) in IER - fed rats.72

Stress resistance has not been assessed however and so the biological relevance of this finding is currently unknown.32 Several IER trials (75 - 85 % ER on restricted days) in overweight / obese populations have reported reductions in various markers of oxidative stress 37, 41, which in one study was accompanied by a complementary increase in the anti-oxidant uric acid.37 In a direct comparison of IER (75 % ER for two days / week) and CER, both ER strategies displayed equal efficacy in reducing levels of fast - acting advanced oxidation protein products (AOPP) after six months, which displayed a tendency to occur earlier (i.e. at three months) in the IER group.41 Levels of slow - acting (i.e. long term) AOPP tended to decrease in the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directions