Sentences with phrase «several of these alterations»

Not exact matches

He said «several officials» at the finance ministry's division in charge of state land sales were involved in the alterations.

Jacci assessed my closet, pulled together a pile of alterations, walked me through the process of getting a custom suit made, and outfitted me with several new pcs.

However, several scholars have suggested that mocked is not a later alteration, but what Mark originally wrote, I believe that Mark took mocked from Psalm 69:9; in his narrative of Jesus» death, Mark weaves together Psalms 22 and 69, as he does other Old Testament passages elsewhere in his Gospel.

While I was raised a Catholic, I do attest that, the bible is often changed to conform to each era, we have many alterations and editing that is involved, as I once sat down with a handful of bibles and compared several passages.

Several months ago, O&W enacted a number of green alterations to its business, including the conversion of its delivery fleet to biodiesel fuel and the replacement of warehouse lighting to energy - efficient and motion - sensor lighting.

[3] The town is named after Paul Busti, an official of the Holland Land Company, but its pronunciation uses a long i sound at the end, a frequent alteration in the names of several upstate New York towns.

The study provides «compelling evidence» of alterations of DNA in several regions of the genome in children with CD, according to Professor Jack Satsangi of University of Edinburgh and colleagues.

Rietveld and full - pattern analysis of the XRD data have revealed a complex mineralogy, with contributions from parent igneous rocks, amorphous components and several minerals relating to aqueous alteration, for example clay minerals and hydrated sulphates.

Another 20 % of patients have alterations causing chromosomal disorganization and the consequent malfunctioning of several genes and proteins.

This cancer is associated with several alterations of the cell's DNA, but it has been unclear which gene or genes are involved in its development.

In the course of this work, he has pioneered several new approaches in the fruit fly that have had important implications for mammalian neurobiology, including: the demonstration that the fruit fly has a sleep - like behavior similar to that of mammals, studies of physiological and behavioral consequences of mutations in a neurotransmitter system affecting one of the brain's principal chemical signals, studies making highly localized genetic alterations in the nervous system to alter behavior, and molecular identification of genes causing naturally occurring variation in behavior.

Mechanistic target of rapamycin (mTOR): Alterations to the mTOR gene and levels of protein produced have been shown to modestly extend life span in several species.

You're looking at several alterations on chromosome 17; the right-most peak is a focal amplification of ERBB2, the gene encoding the Her2 receptor.

It is not always possible to obtain fully normal tissues and thus several of the tissues denoted as normal will include alterations due to inflammation, degeneration and tissue remodeling.

In 2005, the identification of an activating mutation in JAK2 (the V617F mutation) as a STAT5 - activating and disease - causing genetic alteration in a significant proportion of patients with myeloproliferative neoplasms (MPNs) has emphasized the oncogenic role of the JAK tyrosine kinases in hematologic malignancies.2 — 5 JAK2 is a member of the Janus tyrosine kinase family comprising three other mammalian non-receptor tyrosine kinases (JAK1, JAK3 and TYK2) that associate with cytokine receptors lacking intrinsic kinase activity to mediate cytokine - induced signal transduction and activation of STAT transcription factors.6 All JAKs share a similar protein structure and contain a tyrosine kinase domain at the C - terminus flanked by a catalytically inactive pseudokinase domain with kinase - regulatory activity, by an atypical SH2 domain and by a FERM domain that mediates association to the membrane - proximal region of the cytokine receptors.7, 8 Soon after the discovery of JAK2 V617F, we and others described that activating JAK1 mutations are relatively common in adult patients with T - cell acute lymphoblastic leukemia (ALL) and participate in ALL development allowing for constitutive activation of STAT5.9 — 11 Several STAT5 - activating JAK1 mutations were also reported in AML and breast cancer patients.10

Puberty typically begins between 9 and 12 years of age, and creates a surge of hormones that trigger rapid physical growth, sexually dimorphic alterations in facial structure, metabolic changes, and several social, behavioral, and emotional changes (Crone and Dahl, 2012).

Over the past several years, numerous studies have documented alterations in the gut microbiota of people with IBS relative to healthy people.

This may be because steroid hormones cause neurophysiological alterations in the sensory centers of the brain — a process that can take several hours to several days.

The owner of the Nürburgring, Capricorn Nürburgring GmbH, has announced that the speed limits currently enforced on the Nordschleife will be lifted after several circuit alterations are completed in 2016.

Several prototypes were tested that year, but the launch of the Nissan Primera in 1990 prompted Ford to made a number of major alterations to the final product, as it saw the new competitor from Nissan to be the benchmark car in this sector, having previously identified the Honda Accord as the class leader.

Common Feline Anesthetic May Cause Brain Damage: Several studies have hinted that use of ketamine, an anesthetic drug closely related to PCP («angel dust») in children may result in alterations in learning ability and memory.

For example, alterations in the population of intestinal bacteria of the Lactobacillus group are thought to play a role in the development and progression of several neurological disorders, including anxiety / depression, autism, multiple sclerosis and Alzheimer's disease.

Alterations in several growth factor like cytokine or hormone signaling systems have been documented in the pathogenesis of the disease.

Sadly, the alteration of currency did lead to a span of several weeks where it was impossible to find a gift card for Xbox Live as retailers had already removed the Points cards and did not yet have the gift cards.

Notably, the overworld (which underwent several alterations as well) is explored akin to the dungeons, as Link has to make use of his tools and skills to make his way through the areas, as well as to meet the various conditions and items to gain access to the actual dungeons.

The experimentation blossomed into a lifelong obsession that would culminate in his best - known series of paintings, Homage to the Square, in which he painted several differently - colored squares within larger squares in order to illustrate his theory that alterations in environment, shape and light would produce changes in color.

The assessment considered the impacts of several key drivers of climate change: sea level change; alterations in precipitation patterns and subsequent delivery of freshwater, nutrients, and sediment; increased ocean temperature; alterations in circulation patterns; changes in frequency and intensity of coastal storms; and increased levels of atmospheric CO2.

Over the years they have gone through several alterations, and the newest set of federal law limits, established this July 2013 by the Department of Transportation, implements a 30 minute rest requirement to be taken during the first eight hours of a drivers shift.

According to AndroidPit, version 5.1 contains a variety of bug fixes and performance improvements, plus several alterations to the Material Design look introduced with Android Lollipop.

In humans, both the HPA system and the autonomic nervous system show developmental changes in infancy, with the HPA axis becoming organized between 2 and 6 months of age and the autonomic nervous system demonstrating relative stability by 6 to 12 months of age.63 The HPA axis in particular has been shown to be highly responsive to child - caregiver interactions, with sensitive caregiving programming the HPA axis to become an effective physiological regulator of stress and insensitive caregiving promoting hyperreactive or hyporeactive HPA systems.17 Several animal models as well as human studies also support the connection between caregiver experiences in early postnatal life and alterations of autonomic nervous system balance.63 - 65 Furthermore, children who have a history of sensitive caregiving are more likely to demonstrate optimal affective and behavioral strategies for coping with stress.66, 67 Therefore, children with histories of supportive, sensitive caregiving in early development may be better able to self - regulate their physiological, affective, and behavioral responses to environmental stressors and, consequently, less likely to manifest disturbed HPA and autonomic reactivity that put them at risk for stress - related illnesses such as asthma.

Caplan (2010) proposed a model of «problematic Internet use», identifying several specific cognitive and behavioral constructs associated with negative outcomes of the Internet use such as preference for online social interaction, mood alteration, cognitive preoccupation or compulsive behavior.