Sentences with phrase «single cell genomics»

The researchers used single cell genomic sequencing, a very useful and still comparatively new capability.

The Microbial Single Cell Genomics facility in Uppsala is already operational and aims to provide a broad range of single cell genomics services.

Recognizing the remarkable opportunities to apply single cell technologies to major questions in biology and medicine, JAX recently launched a joint center for single cell genomics together with the University of Connecticut, including UConn Health.

Single cell genomics allows the separation and isolation of cells to extract and sequence individual parasite DNA and determine any differences between the parasites within an infection.

«There are many efforts around the world to systematically determine the transcript levels in cells, tissues and organs, involving new technologies such as single cell genomics and spatial transcriptomics».

With single cell genomics, we have a tool that gives us this information from each individual, with all their diversity included.

The combination of these methods enables complex tissues to be studied by single cell genomics workflows, revealing interrelationships between molecular and cellular phenotypes within tumor microenvironments.

Using the oral microbial community as a model system, we are applying functional genomic approaches including Stable Isotope Probing (SIP), metatrascriptomics and directed single cell genomic approaches to enable us to overcome this limitation.

His lab develops novel single cell genomic and epigenomic methods to characterize the immune system and develop new targets for immunotherapy.

Our experience in single cell genomics is unique in Spain and suits research on virtual every species, tissue or disease context.

Single cell genomics means that one can study the genetic material of single cells.

I started working on my current project revolving around single cell genomics!

During the fall of 2011 he first became involved in SciLifeLab when helping to start up the facility for single cell genomics, which he is also director of.

«A common problem in the field of single cell genomics is the inability to validate mutations that are detected in individual cells,» said Yong Wang, Ph.D., a postdoctoral fellow in the Department of Genetics and first author on the study.

Single cell genomics allow us to take a drop of water from any pond around the globe, separate the microorganisms it contains and classify them individually according to their genetic information.

My lab is dedicated to explore the vast uncharacterized microbial diversity using cutting - edge culture independent technologies, such as single cell genomics and metagenomics.

«It's the same process as for single cell genomics, but for aggregates of symbiotic bacteria and archaea,» said DOE JGI Microscale Applications Group head Rex Malmstrom of the technique called BONCAT - FACS (BONCAT — Fluorescence - Activated Cell Sorting).

In the recent years, culture - independent methods, such as metagenomics and single cell genomics have been developed that allow for the genomic exploration of this so - called «microbial dark matter».

«Single cell genomics can be applied to understand the heterogeneity of tumors, to explain how genetically identical cells may show distinct behavior, and to explore the vast, uncharacterized microbial landscape.

Currently, we are exploring several environmental samples retrieved from allover the world - ranging from hydrothermal vents in Japan to hot springs in Yellowstone National Park and New Zealand — for the presence of novel archaeal (and bacterial) lineages using cultivation - independent approaches, such as metagenomics and single cell genomics.

Single cell genomics is an emerging technology enabling the exploration of genomes of individual microbial cells without the need for prior cultivation.

Single cell genomics of uncultured marine alveolates shows paraphyly of basal dinoflagellates — Jürgen F H Strassert, ISME

Scientific programs include: human genomic sequencing and analysis, synthetic genomics and exploration of new vaccines using this technology, and environmental and single cell genomics to explore the vast unseen world of microbes living in the human body, the ocean, soil and air.

Indeed, as we ride the waves of single cell genomics — and genome sequencing and editing, too — we can see further than ever before.

Connection to SciLifeLab: Director at the Single cell genomics facility.

Paul Robson, who serves as JAX Genomic Medicine's director of single cell genomics, believes the work of the new center will be critical to advancing the goals of precision medicine: «If you want better insight into how biology works, you need to look at its fundamental unit,» he says.

Although the field of single cell genomics is still fairly new, it is already becoming clear that cells once thought to be genetically similar, if not identical, are in fact quite different.

Single cell genomics: thinking small by Iain Macaulay We all emerged from a single cell and it only takes a mutation in a single cell to cause disease.

Together with Anna - Maria Divne, I am setting up and establish methods for single cell genomics, from single cell sorting, to whole genome amplification, target screening and sequencing library preparation.Why can you find me on this homepage?

Our single cell genomics toolkits allow us to deconvolute sample and tissue heterogeneity and to track dynamic changes throughout stimulation or perturbation.