Sentences with phrase «small brain models»

«Problematic relationship: Small brain models distort contact intensity between neurons.»

Not exact matches

The system mimics the «homunculus model of mind» — the idea that there's a small human inside our brains controlling our actions, viewing the images we see and understanding them for us.

In a model of glioblastoma, a brain cancer that does not metastasize outside of the brain, they could readily see that the length of circulating tumor DNA was smaller than healthy DNA by 20 - 50 base pairs.

An international team of researchers has shown that a new small - molecule drug can restore brain function and memory in a mouse model of Alzheimer's disease.

In a novel animal study design that mimicked human clinical trials, researchers at University of California, San Diego School of Medicine report that long - term treatment using a small molecule drug that reduces activity of the brain's stress circuitry significantly reduces Alzheimer's disease (AD) neuropathology and prevents onset of cognitive impairment in a mouse model of the neurodegenerative condition.

By using the smaller and less complex cricket brain as a model, Dr. Adamo hopes to uncover more broad patterns of nervous system function in both immune responses and, of course, behavior.

Blocking this process with a small - molecule drug prevented the characteristic brain plaques and memory loss in a mouse model of the disease.

In the March issue of Scientific American Carl Schoonover, author of Portraits of the Mind: Visualizing the Brain from Antiquity to the 21st Century, describes a new computer - modeling technique that allows researchers to zoom in on the smallest components of the active brain in 3Brain from Antiquity to the 21st Century, describes a new computer - modeling technique that allows researchers to zoom in on the smallest components of the active brain in 3brain in 3 - D.

Now, a study in the journal Brain describes what could be considered a direct «aquarium - to - bedside» approach, taking a drug discovered in a genetic zebrafish model of epilepsy and testing it, with promising results, in a small number of children with the disease.

Their model is the fruit fly, a master in motion vision, possessing a relatively small brain.

iTeos is now developing EOS200271 which is a synthetic, small molecule inhibitor of indoleamine 2,3 - dioxygenase (IDO1), which has demonstrated the same anti-tumour activity in multiple preclinical tumour models in combination with immune checkpoint inhibitors as competitors, but also has demonstrated superior brain penetration.

«This study provides proof - of - concept experiments, in large animal models, that a small, miniaturized device can be safely implanted in the brain and provide miniaturized control of the electrical activity and function of single neurons or small groups of neurons.

These plaques are extracellular aggregations of a small protein called beta - amyloid that are prominent in diseased patients» brains, as well as in mouse models of the disease.

The core facility is a two - photon in vivo imaging platform developed at the Nonlinear bioimaging laboratory, a technique that allows for non-invasive structural and functional measurements in small animal models at different scales: from macroscopic imaging of the brain morphology to highly resolved microscopy of neuron populations, single neurons, and even subcellular structures.