Tobias Heckel (Hoflack, TUD)-- «Revealing
Src tyrosine kinase - dependent signaling pathways in osteoclasts: Implications on actin organization and cell polarity» (2008)
Not exact matches
Therefore, a team led by Vladimir Tesar, MD, PhD (Charles University and General University Hospital, in the Czech Republic) tested the potential of an investigational drug called bosutinib that inhibits a particular
tyrosine kinase called
Src / Bcr - Abl.
Disruption of Ca2 + - dependent cell - matrix adhesion enhances c -
Src kinase activity, but causes dissociation of the c -
Src / FAK complex and dephosphorylation of
tyrosine - 577 of FAK in carcinoma cells.
Variola and monkeypox viruses utilize conserved mechanisms of virion motility and release that depend on Abl and
Src family
tyrosine kinases.
We also found that the
SRC and ABL non-receptor
tyrosine kinases and the SHEP1 scaffolding protein are binding partners of the Eph receptors, and we identified signaling connections between Eph receptors and integrins.
The tumor suppressor DAPK is reciprocally regulated by
tyrosine kinase Src and phosphatase LAR.