Sentences with phrase «stem cell expansion»

Rational Bioprocess Design for Human Pluripotent Stem Cell Expansion and Endoderm Differentiation Based on Cellular Dynamics.

StemXVivo ® GMP Mesenchymal Stem Cell Expansion Media - Thaw the MSC Expansion Media at 2 - 8 °C or room temperature.

Not exact matches

Mr Blair also used his trip to California to woo researchers in stem cell science to come to the UK, after Mr Bush used his first presidential veto to block the further expansion of federal investment in this area of research.

U.S. stem cell scientists breathed a sigh of relief this July when a federal judge upheld the Obama administration's expansion of stem cell research.

Previous trials of retinoids against breast cancer have been conducted only after anti-estrogen treatments, at which point, «we were already getting expansion of cancer stem cells — treating with a retinoid after that was already too late,» Fettig says.

Sheng Ding, PhD, a senior investigator in the Roddenberry Stem Cell Center at Gladstone and co-senior author on the study, adds, «This new cellular reprogramming and expansion paradigm is more sustainable and scalable than previous methods.

Neural stem cells called outer radial glial (oRG) cells help fuel the expansion of the unusually big human brain.

The approach enabled a wide range of studies of human brain development, including implicating a new class of neural stem cell recently discovered by the lab in the evolutionary expansion of the human brain and identifying how the mosquito - borne Zika virus may contribute to microcephaly in infants infected in utero.

The group observed that, at the cellular level, one of the side effects of the diet was an expansion of hair follicle stem cells, leading to increasing hair follicle growth and retention rates.

In studies of neural development in mice, Stahl found that TRNP1 produces a protein that determines whether neural stem cells self - replicate, leading to a balloonlike expansion of cortical surface area, or whether they differentiate into a plethora of intermediate stem cell types and neurons, thickening the cortex and forming more complex brain structures.

«A few weeks after they are born,» says Dr. Enikolopov, «the pituitary undergoes massive expansion» that suggests a role for adult stem cells.

First, the MimEX ™ Cell Plating Procedure is used to maintain a uniform irradiated fibroblast monolayer for the rapid clonal expansion and efficient differentiation of tissue - specific adult epithelial stem cells.

A few years ago, Dr. Funderburgh and other University of Pittsburgh researchers identified stem cells in a layer of the cornea called the stroma, and they recently showed that even after many rounds of expansion in the lab, these cells continued to produce the biochemical components, or matrix, of the cornea.

For the expansion and differentiation of human keratinocyte stem cells for permanent skin restoration in victims of extensive burns.

MimEX ™ Tissue Models System provides a platform for the isolation, expansion, and differentiation of adult epithelial stem cells into 3 - D ex vivo organ tissue.

Expansion of embryonic and adult neural stem cells by in utero electroporation or viral stereotaxic injection.

Using Cultrex ® BME, MimEX ™ Tissue Models System provides a platform for the isolation, expansion, and differentiation of adult epithelial stem cells into 3 - D ex vivo organ tissue.

Benedetta Artegiani (Calegari, TUD)-- «A Transitory Overexpression of Cdk4 / CyclinD1 Triggers a Greater Expansion of Neural Stem Cells and Neurons in the Adult Mouse Brain» (2012)

In his spare - time, Riggs promotes the expansion of the Student Society for Stem Cell Research (SSSCR).

Expansion and maintenance of human embryonic stem cell - derived endothelial cells by TGFbeta inhibition is Id1 dependent.

Next Bruno Chilian from Evotec presents work using stem cells specially engineered to study the CAG genetic expansion that causes HD.

To culture embryonic stem cells on LN521 enables easy and efficient expansion of your hESCs and iPSCs and provides a biorelevant in vitro stem cell niche.

Overexpression of cdk4 and cyclinD1 triggers greater expansion of neural stem cells in the adult mouse brain.

Specially formulated to enhance single cell expansion in the cloning step of stem cell genome editing, StemFit Basic02 offers superior and stable growth performance, high colony forming efficiency and robust scalable cell expansion.

Cost - effective creation of biofunctionalised scaffolds, tailored to function as stem cell niches for expansion, transport and delivery.

Finally, we show that addition of small molecule inhibitors of eIF2α dephosphorylation to muscle stem cell cultures permits their ex vivo expansion and engraftment into a preclinical mouse model of Duchenne muscular dystrophy.

The DEF - CS system is a robust culture system for efficient expansion of human induced pluripotent stem (iPS) cells in a feeder - free and defined environment.

Stem cell polarity is established by the PAR complex, comprised of PAR3 / PAR6 / aPKC, to regulate self - renewal and expansion.

Regina Duryagina (Bornhäuser, TUD)-- «Role of Jagged - 1 and extracellular matrix components for the maintenance of hematopoietic stem and progenitor cells during ex-vivo expansion» (2013)

Christian Lange (Calegari, TUD)-- «Cdk4 / CyclinD1 Overexpression in Neural Stem Cells Shortens G1, Delays Neurogenesis, and Promotes the Generation and Expansion of Basal Progenitors» (2010)

Dissertation work led to phenotypic validation of a novel gene for the scale - up and expansion of stem cells.

I have read and collected info about each clinical trial to include sponsor, trial status, country, donor source, disease indication, cell expansion, stem cell dosages, etc. so this could get very interesting!

The in vitro expansion of muscle stem cells (MuSCs), also known as satellite cells, may provide a potent means to treat a wide range of muscle - related diseases such as sarcopenia and muscular dystrophy.

The portfolio includes U.S. and foreign patents and applications directed to culture, expansion and scale - up of pluripotent stem cells and cell types derived therefrom, various differentiation processes for production of mesendoderm, definitive endoderm, PEC - 01, and endocrine precursors, as well as claims directed to the Company's Encaptra ® macro-encapsulation device platform.

Grinenko T, Arndt K, Portz M, Mende N, Günther M, Cosgun KN, Alexopoulou D, Lakshmanaperumal N, Henry I, Dahl A, Waskow C Clonal expansion capacity defines two consecutive developmental stages of long - term hematopoietic stem cells.

A new study demonstrates how a three - dimensional culture substrate can help to maintain the number of primitive stem cells present during the expansion...

Judson RN, Quarta M, Oudhoff MJ, et al., Inhibition of Methyltransferase Setd7 Allows the In Vitro Expansion of Myogenic Stem Cells with Improved Therapeutic Potential.

Bone marrow - derived mesenchymal stem cells (BM - MSCs) are obtained by isolating mononucleated cells from a marrow aspirate by centrifugation on a density gradient, followed by adherent cell expansion in tissue culture.

The order severely restricts embryonic stem cell research to existing lines of cells and bans federal funding for any research expansion outside his directive.

Review of «Inhibition of Methyltransferase Setd7 Allows the In Vitro Expansion of Myogenic Stem Cells with Improved Therapeutic Potential» from Cell Stem Cell by Stuart P. Atkinson

«With the new stem cell model, however, we hope eventually to put together a much more detailed picture of this process of repeat expansion and gene silencing, and that should put us in a good position to devise optimal therapies,» Gottesfeld said.

«With the new stem cell model, we hope eventually to put together a much more detailed picture of this process of repeat expansion and gene silencing, and that should put us in a good position to devise optimal therapies,» says Professor Joel Gottesfeld.

After creating a stem cell model of the disease from patients» skin cells, the Scripps Research scientists found strong evidence for the involvement of a DNA repair enzyme in the FXN triplet repeat expansion.

In vitro expansion of single Lgr5 + liver stem cells induced by Wnt - driven regeneration.

«In the transition from skin cells to stem cells, and then as the stem cells grew in culture and divided to produce their own daughter stem cells, the triplet repeat expansions within FXN became longer,» said Ku.

Due to the large number of hES cells and human induced Pluripotent Stem (hiPS) cells needed by I - Stem's research groups, the development of large - scale culture systems for expansion and differentiation of those cells is critical.

The scientists» studies also showed that AIM2 played a role independent of its immune role, in suppressing abnormal expansion of intestinal stem cell populations.

The remarkable size expansion of the human neocortex is thought to partly arise from a second pool of neural stem cells, called the basal Radial Glial (bRG) cells (Fig. 1).

In addition, we wish to characterize how variations in neural stem cells behavior may account for the large expansion of the human brain, but also how alterations may lead to pathological brain development.

Zonari E, Desantis G, Petrillo C, Boccalatte FE, Lidonnici MR, Kajaste - Rudnitski A, Aiuti A, Ferrari G, Naldini L, Gentner B. Efficient ex vivo engineering and expansion of highly purified human hematopoietic stem and progenitor cell populations for gene therapy.