on Poseida Announces Initial Phase 1 Data for P - BCMA - 101 CAR - T
Stem Cell Memory Product in Patients with Relapsed / Refractory Multiple Myeloma
Poseida Announces Initial Phase 1 Data for P - BCMA - 101 CAR - T
Stem Cell Memory Product in Patients with Relapsed / Refractory Multiple Myeloma
Not exact matches
Neural
stem cells with the ability to form new neurons in the brain are normally present in the hippocampus (the part of the brain connected to learning and
memory) and in the subventricular zone of the brain.
Healthy people in their 70s have just as many young nerve
cells, or neurons, in a
memory - related part of the brain as do teenagers and young adults, researchers report in the April 5
Cell Stem Cell.
In the hippocampus, a brain region vital for laying down new
memories, «
stem cells continue to add new circuit elements,» says Stanford University neuroscientist Theo D. Palmer, who helped Monje find out why brain fogginess can persist for years after cancer treatment has ended.
When the researchers tracked the
stem cells in the mice's brains, they saw that only about 5 percent of them actually developed into neurons, suggesting the
cells did not rescue
memory by replacing dead neurons, LaFerla says.
«We began with
stem cells taken from cord - blood, which have fewer acquired mutations and little, if any, epigenetic
memory, which
cells accumulate as time goes on,» says Zambidis, associate professor of oncology and pediatrics at the Johns Hopkins Institute for
Cell Engineering and the Kimmel Cancer Center.
Neuroscientists Jing Wang and Freda Miller, both then at Toronto's Hospital for Sick Children, showed that when nondiabetic mice are given metformin, their
memory improves, thanks to an increase in the neural
stem cell population and in the number of these
cells that develop into healthy neurons in the hippocampus, the brain's
memory center.
After concluding that increased
stem cell production in a certain area of the brain had a positive effect on behavioral deficits of Alzheimer's, Prof. Offen has moved to research into the area of the brain that controls
memory.
His group showed that a small number of
stem -
cell like CD8 T
cells - called «
memory»
cells - were enough to produce and repeatedly replenish all of the T - effector
cells needed to fight the disease.
In mice and humans alike, the cerebral cortex — the outermost layer of brain tissue associated with high - level functions such as
memory and decision - making — starts out as a spherical sheet of tissue made up of only neural
stem cells.
Mice with human astrocytes performed better on
memory experiments than those that had received mouse
cell grafts, the team reports today in Cell Stem C
cell grafts, the team reports today in
Cell Stem C
Cell Stem CellCell.
Buried deep underneath the folds of the cerebral cortex, neural
stem cells in the hippocampus continue to generate new neurons, inciting a struggle between new and old as the new attempts to gain a foothold in
memory - forming center of the brain.
«This is very promising because
stem cells play an important role in learning,
memory and regeneration.»
But one glimpse came in 2013, when scientists transplanted human neural
stem cells into the brains of mice which had damage in regions responsible for learning and
memory.
The scientists implanted neural
stem cells into the hippocampus, which is a brain region involved in making new
memories and connecting them to emotions.
While the exact contribution adult - born neurons make to overall learning and
memory remains mysterious, Song notes that these results are promising for any future nerve
stem cell therapy.
Warren D. Shlomchik, M.D. Yale University
Memory T
cells for improved immune reconstitution and GVL in allogeneic hematopoietic
stem cell transplantation
FLATOW: There's another study out this week showing epigenetic differences between induced
stem cells and embryonic
stem cells, that induced
stem cells had a
memory, basically.
Germany, still wrestling with dark
memories of Nazi - era eugenics and human experimentation, is cautious about genetics and
stem cell research.
Citation: Marchetto MCN, Yeo GW, Kainohana O, Marsala M, Gage FH, Muotri AR (2009) Transcriptional Signature and
Memory Retention of Human - Induced Pluripotent
Stem Cells.
New UC Irvine research is among the first to demonstrate that neural
stem cells may help to restore
memory after brain damage.
«
Stem Cells Can Improve
Memory After Brain Injury.»
In the study, mice with brain injuries experienced enhanced
memory — similar to the level found in healthy mice — up to three months after receiving a
stem cell treatment.
They found that only about 4 percent of them turned into neurons, indicating the
stem cells were not improving
memory simply by replacing the dead brain
cells.
Clearing out the entire immune system, all of its
memory and quirks, and restarting it fresh with a new supply of
stem cells is a good approach to many of the issues in the aged immune system.
The scientists then set out to learn whether neural
stem cells from a mouse could improve
memory in mice with brain injuries.
Scientists then could spend less time coaxing
stem cells to turn into other types of
cells, at least as it relates to
memory research.
Marie - Dominique Filippi, PhD, PhD Cincinnati Children's Hospital Medical Center Cincinnati, OH Mitochondrial Morphology Controls Hematopoietic
Stem Cell Self - Renewal and Confers Them Divisional
Memory
Electronic
memory boosters
stem from research on the brain's ability to change and adapt over time by generating new brain
cells and forming new neural pathways.
Researchers are now taking advantage of the
memories of
stem cells produced from adult
cells to provide new possibilities for individuals having type 1 diabetes, which impacts 3 million individuals in the US.
Develops new nerve
cells from the
stem cells (blank
cells) in the hippocampus, which is the part of the brain related to
memory and learning.
«Statins make regular users become older faster, leaving them open to long - term mental and physical decline, according to disturbing new research... Scientists have found the heart disease drug badly affects our
stem cells, the internal medical system which repairs damage to our bodies and protects us from muscle and joint pain as well as
memory loss.»