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Not exact matches
The process takes a person's
cells (blood,
skin) and converts them into
stem cells.
According to Science Daily, Dr. Nagy, senior investigator at the Samuel Lunenfeld Research Institute of Mount Sinai Hospital, there is a «new method of generating
stem cells that does not require embryos as starting points and could be used to generate
cells from many adult tissues such as a patient's own
skin cells.»
One of the key caveats at the time, however, was that the technique required the use of a virus to introduce several genes into the
skin (or other)
cell, and these would remain in the
cell, and so might contaminate the resulting
stem cell or create cancer risks.
Scientists looking for new methods to make human tissue have successfully used cloning technology to create embryonic
stem cells from
skin cells.
Embryonic
stem cells are produced during development by the same process of epigenetic programming that later will produce adult
cells such as
skin and brain.
We referred to the news that these
cells, called induced pluripotent
stem cells (iPSCs), could be made from human
skin....
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While scientists have previously had success in 3D printing a range of human
stem cell cultures developed from bone marrow or
skin cells, a team from Scotland's Heriot - Watt University claims to be the first to print the more delicate, yet more flexible, human embryonic
stem cells (hESCs).
Frankenbunnies Embryos made by Chinese researchers who fused human
skin cells with rabbit eggs, hoping to create a source of
stem cells.
Treating the
skin cells with a biochemical cocktail to promote neural
stem cell characteristics seemed to do the trick, turning it into a one - step process, he and his colleague report today in Science Translational Medicine.
To make the HSCs, the Harvard group used human
skin cells to create induced pluripotent
stem cells (iPSCs), adult
cells researchers genetically reprogram to an embryonic -
stem -
cell state, where they can grow into any kind of
cell.
To solve these problems, Hingtgen's group wanted to see whether they could skip a step in the genetic reprogramming process, which first transforms adult
skin cells into standard
stem cells and then turns those into neural
stem cells.
The researchers dialed the
skin cells back, developmentally speaking, to produce induced pluripotent
stem cells (iPSCs)-- a special type of
cell that can both self - renew, making more iPSCs, and differentiate, specializing into almost any other
cell type.
The idea fell out of favour following the scandal of 2005, and after the development of a way to turn ordinary
skin cells into so - called induced pluripotent
stem cells (iPS
cells), which behave rather like hESCs.
To develop their «disease in a dish» model, the team took
skin cells from patients with Allan - Herndon - Dudley syndrome and reprogrammed them into induced pluripotent
stem cells, which then can be developed into any type of tissue in the body.
Toxicologist Thomas Hartung described these minibrains, grown from
stem cells derived from people's
skin cells, at the annual meeting of the American Association for the Advancement of Science.
The researchers say that they can grow the stomach organoids from both embryonic
stem cells and
skin cells induced to pluripotency.
«In effort to treat rare blinding disease, researchers turn
stem cells into blood vessels: Patients around the world contribute
skin samples to test potential new therapy.»
Since 2006, researchers have been able of take differentiated specialized
cells, like
skin cells, and transform them into induced pluripotent
stem cells or iPSCs.
«This new study uncovers for the first time the dynamic of
stem cells during wound healing and identifies new molecular players associated with
skin regeneration.
Beginning in the 1970s, physicians learned how to harvest
skin stem cells from a patient with extensive burn wounds, grow them in the laboratory, then apply the lab - grown tissue to close and protect a patient's wounds.
«It was particularly exciting to observe that the repair of the
skin epidermis involves the activation of very different
stem cells that react the same way to the emergency situation of the wound and have the power to completely restore the damaged tissue», comments Mariaceleste Aragona, the first author of the study.
Cellular reprogramming turns an adult
cell, such as a
skin cell, into an induced pluripotent
stem (iPS)
cell.
So Izpisúa Belmonte and his colleagues harvested fibroblasts, which are far more common than
stem cells, from the
skin of people with the bone marrow disease Fanconi anaemia.
Anand and his colleague Susan McKay started with human
skin cells, which they turned into induced pluripotent
stem cells (iPSCs) using a tried - and - tested method.
Using a mathematical model known as the Ising model, invented to describe phase transitions in statistical physics, such as how a substance changes from liquid to gas, the Johns Hopkins researchers calculated the probability distribution of methylation along the genome in several different human
cell types, including normal and cancerous colon, lung and liver
cells, as well as brain,
skin, blood and embryonic
stem cells.
The neural progenitor
cells used were derived from iPSCs (induced pluripotent
stem cells), which were in turn derived from donor
skin cells.
Further preclinical work will be needed to use the herpes - loaded
stem cells for breast, lung and
skin cancer tumors that metastasize to the brain.
Scientists may have turned mouse
skin cells into embryolike
stem cells, but prior claims for the power of adult
cells have yet to stand the test of time
In 2006, Japanese scientists figured out how to reprogram specialized
cells, such as those in
skin, so that they act like embryonic
stem cells.
Wells's team first turned human
skin cells into pluripotent
stem cells, which can grow into any type of tissue.
Finally, he would suck out
stem -
cell - rich fat from the patient's belly and inject it into a layer under the dermis to replenish the fat that keeps
skin elastic and soft.
To investigate the role of astroglia in Down syndrome, the research team took
skin cells from individuals with Down syndrome and transformed them into
stem cells, which are known as induced pluripotent
stem cells (iPSC).
A TECHNIQUE for making
stem cells from adult
skin cells without tinkering with their DNA could herald a breakthrough in the quest for
stem -
cell therapies that do not rely on embryo - derived
cells.
The research was supported by the National Science Foundation Graduate Research Fellowship Program, the National Institute of Arthritis and Musculoskeletal and
Skin Diseases of the National Institutes of Health, the Rose Hills Foundation Research Award, the California Institute for Regenerative Medicine's Bridges Program and the UCLA Broad
Stem Cell Research Center.
A promising alternative to hESCs emerged in 2006 when researchers produced so - called induced pluripotent
stem cells (iPS) from ordinary tissue such as
skin.
There are now other methods to make
stem cells, but those made via SCNT have unique value because they are genetic copies of the living person who donated the
skin cells (other methods either use foreign
cells or involve genetic reprogramming).
Last year Loring transformed
skin cells from the drill, a silver - bearded African monkey, into a pluripotent
stem cell that can form many different tissue types.
They also found that saliva contains another class of small RNAs, called piwi - interacting RNAs, or piRNAs, which are produced by
stem cells,
skin cells and germ
cells.
They then tried to reprogram
skin cells from the animals, turning them into induced pluripotent
stem cells (iPS), which are capable of forming other types of
cell.
Thanks to crucial contributions from three young lab members, he said, his team succeeded in converting mature
skin cells into pluripotent
stem cells.
This year they succeeded in generating mini-livers, or liver buds, from
stem cells that were taken from human
skin and reprogrammed to an embryonic state.
In May 2013, Mitalipov was the first scientist in the world to demonstrate the successful use of somatic
cell nuclear transfer, or SCNT, to produce human embryonic
stem cells from an individual's
skin cell.
In a last - ditch effort to save a dying 7 - year - old boy, scientists have used
stem cells and gene therapy to replace about 80 percent of his
skin.
The research team took
skin fibroblast tissue from adult mole - rats and reprogrammed the
cells to revert to pluripotent
stem cells.
In one promising approach, cellular reprogramming,
stem cells can be generated by fusing adult
skin cells with embryonic
stem cells from existing
cell lines.
The new epidermis, grown from human pluripotent
stem cells, offers a cost - effective alternative lab model for testing drugs and cosmetics, and could also help to develop new therapies for rare and common
skin disorders.
Zheng, together with Leah Boyer, then a researcher in Gage's lab and now director of Salk's
Stem Cell Core, generated diseased neurons by taking skin cells from patients with Leigh syndrome, reprogramming them into stem cells in culture and then coaxing them to develop into brain cells in a d
Stem Cell Core, generated diseased neurons by taking
skin cells from patients with Leigh syndrome, reprogramming them into
stem cells in culture and then coaxing them to develop into brain cells in a d
stem cells in culture and then coaxing them to develop into brain
cells in a dish.