Sentences with phrase «stem cells study shows»

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Studies have shown that these cancer - fighting compounds and enzymes found in broccoli and other cruciferous vegetables may actually prevent the relapse of certain cancers by killing cancer stem cells.

In 2010, researchers from the University of Michigan Comprehensive Cancer Center published a study in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cells.

«In directing stem cells, study shows context matters.»

Now, in a new study published today, Sept. 8, in the Proceedings of the National Academy of Sciences, a team of researchers from the University of Wisconsin - Madison has added a new wrinkle to the cell differentiation equation, showing that the stiffness of the surfaces on which stem cells are grown can exert a profound influence on cell fate.

For example, animal studies have shown that neurons derived in the lab from human embryonic stem cells improve Parkinson's symptoms; however, any residual stem cells associated with those neurons could form masses of unwanted cells.

And while cytochalasin D might not be the actual agent scientists use to trigger bone formation in the clinic, Rubin's study shows that triggering actin transport into the nuclei of cells may be a good way to force mesenchymal stem cells to become bone cells.

Pre-clinical studies have shown it to be effective in eliminating a number of different kinds of cancers cells, including cancer stem cells from human breast cancer patient biopsies.

«Our stem cell - based studies indicate that low - calorie sweeteners promote additional fat accumulation within cells compared with cells not exposed to these substances, in a dose - dependent fashion — meaning that as the dose of sucralose is increased more cells showed increased fat droplet accumulation,» said Sabyasachi Sen, M.D., Associate Professor of Medicine at George Washington University in Washington, D.C. «This most likely occurs by increasing glucose entry into cells through increased activity of genes called glucose transporters.»

While some previous studies found that maintenance lenalidomide after autologous hematopoietic stem cell transplant improved overall survival for newly diagnosed multiple myeloma patients, others showed no benefit to this approach.

Hwang claimed his stem cells did not result from parthenogenesis, but George Daley, head of the study, showed that the genome of Hwang's cell line has a genetic signature that indicates it sprang from a parthenogenetic embryo.

Mouse studies published this week in Cell and its sister journal Cell Stem Cell and in Nature show precisely how the virus slows fetal growth, damages the brain, and leads to miscarriage.

A study in the International Society for Stem Cell Research's journal Stem Cell Reports, published by Cell Press on November 20 shows that a Sox2 protein, alone or in combination with another protein, Ascl1, can cause nonneuronal cells, called NG2 glia, to turn into neurons in the injured cerebral cortex of adult mice.

A few studies showed that stem cells from bone marrow could create scar tissue.

In the study published in the journal Science Signaling, the team led by LLuís Espinosa, investigator of IMIM's research group into stem cells and cancer, have shown that inhibition of endosomal activity is a potential therapeutic strategy for the treatment of cancers with the BRAF mutated gene.

This study shows that the mesenchymal subtype is the most aggressive subtype, that it has the poorest prognosis among affected patients, and that cancer stem cells isolated from the mesenchymal subtype have significantly higher levels of the enzyme ALDH1A3 compared with the proneural subtype.

Semenza says previous studies have shown that resistance to chemotherapy arises from the hardy nature of cancer stem cells, which are often found in the centers of tumors, where oxygen levels are quite low.

Recent studies showed that low oxygen conditions increase levels of a family of proteins known as HIFs, or hypoxia - inducible factors, that turn on hundreds of genes, including one called NANOG that instructs cells to become stem cells.

Studies in diabetic mice, also presented in Cell Stem Cell, show that the drug can reverse the colon damage.

A 2010 study in Stem Cells and Development showed that fetal cells can migrate to the brain of a mother mouse and mature into neurons, Nelson Cells and Development showed that fetal cells can migrate to the brain of a mother mouse and mature into neurons, Nelson cells can migrate to the brain of a mother mouse and mature into neurons, Nelson says.

They also published findings from an animal study showing that the effect of stem cell therapy following heart attack is indirect — the stem cells themselves do not survive long after being placed in the heart, but they cause enduring effects by stimulating the rapid growth of surviving heart tissue and attracting stem cells already in the heart, which mature into functional heart cells.

«This pilot study showed that the culture system not only allowed for efficient propagation of sperm stem cells, but also eliminated ALL cells,» said Sadri - Ardekani.

Some of the first evidence for cancer stem cells came from studies of leukemia in the 1990s, which showed that only a small subset of the cancerous blood cells could propagate the disease in mice.

Ko first cloned the human GT198 gene while a postdoctoral fellow at Harvard Medical School, and subsequent studies by her and others have shown it has multiple roles that also include regulating stem cells, cell suicide and turning other genes off and on.

In a study being published in the journal Neuron, researchers show that the signal molecule TGF - beta acts as a time signal that regulates the nerve stem cells» potential at different stages of the brain's development — knowledge that may be significant for future pharmaceutical development.

This study shows that the stem cells behave as you would like them to and they appear safe, says Roger Barker of the University of Cambridge.

«However, our study has shown that even by making fairly modest changes in temperature we can activate our stem cells to form brown fat at a cellular level.

In a new study published in Science, the laboratory of Sebastian Jessberger, professor in the Brain Research Institute of the University of Zurich, has shown for the first time the process by which neural stem cells divide and newborn neurons integrate in the adult mouse hippocampus.

In the new study, Lipton and his colleagues used human stem cell and mouse models to show exactly how SNO can trigger cell death in Parkinson's disease.

Previous studies have shown that a small molecule known as ONC201 currently in advanced cancer clinical trials, targets self - renewing colorectal cancer stem cells.

The study, published in Nature Medicine on November 16, 2015, is the first to show that Duchenne muscular dystrophy directly affects muscle stem cells.

«For nearly 20 years, we've thought that the muscle weakness observed in patients with Duchenne muscular dystrophy is primarily due to problems in their muscle fibres, but our research shows that it is also due to intrinsic defects in the function of their muscle stem cells,» said Dr. Michael Rudnicki, senior author of the study.

In the fruitfly testis niche, previous studies have shown that different stem cell types had to coordinate with each other.

A new study by researchers at Karolinska Institutet in Sweden shows how an unexpectedly high number of mutations in the stem cells of muscles impair cell regeneration.

«Patient's own stem cells could clear a cloudy cornea, study shows.»

Dr Mohamed Elrayess, from ADLQ, said: «In this study we have shown that the impaired ability of fat stem cells to store excess fat was partially due to increased levels of the inflammatory marker interleukin - 6 in the blood.

This study provides experimental evidence which shows the important role of RNA levels in the controlling the fate of embryonic stem cells, and shows an understanding of RNA's ability to differentiate stem cells at the molecular level.

In a study led by Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research member Dr. Julian Martinez - Agosto, UCLA scientists have shown that two genes not previously known to be involved with the immune system play a crucial role in how progenitor stem cells are activated to fight infectStem Cell Research member Dr. Julian Martinez - Agosto, UCLA scientists have shown that two genes not previously known to be involved with the immune system play a crucial role in how progenitor stem cells are activated to fight infectstem cells are activated to fight infection.

Using the Drosophila melanogaster fruit fly as a model organism, the team led by Prof. Dr. Ingrid Lohmann at Heidelberg University's Centre for Organismal Studies was able to show how a special developmental gene from the Hox family influences germline stem cells.

«Multiple myeloma patient study shows promise for natural killer cells: Phase I study included combination with high - dose chemotherapy and stem cell transplantation.»

The authors say it's the first study to show RNA splicing modulators inhibit cancer stem cell activity.

Thorough study of changes in the gene activity regulation mechanism showed that reprogrammed and embryonic stem cells are similar.

The study recently published in «Cell Stem Cell» also shows that signals secreted by the choroid plexus dynamically change during aging which affects aged stem cell behavCell Stem Cell» also shows that signals secreted by the choroid plexus dynamically change during aging which affects aged stem cell behavStem Cell» also shows that signals secreted by the choroid plexus dynamically change during aging which affects aged stem cell behavCell» also shows that signals secreted by the choroid plexus dynamically change during aging which affects aged stem cell behavstem cell behavcell behavior.

«Molecular competition drives adult stem cells to specialize, study shows.»

A new study in rats shows that lacing a penis graft with adult stem cells yields better healing and sexual function than using the graft alone.

Now, in a study recently published in the journal PLOS ONE, a team of scientists from VCU Massey Cancer Center have shown a genetic relationship between the reactivation of hCMV and the onset of graft - versus - host disease (GVHD), a potentially deadly condition in which the immune system attacks healthy tissue following a bone marrow or stem cell transplant.

In the study, the protein Miro1 was shown to regulate the transfer of mitochondria from mesenchymal stem cells to epithelial cells.

The Stowers study is the first to show that hematopoietic stem cells (the parent cells) can be directly controlled by their own progeny (megakaryocytes).

«Our results show that the movement of mitochondria from stem cells to recipient cells is regulated by the protein Miro1 and is part of a well - directed process,» remarked Anurag Agrawal, Professor at the CSIR - Institute of Genomics and Integrative Biology in Delhi, India, and one of the lead authors of the study.

«We were able to show that the stem cells divide differently in these patients,» explains associate professor Dr. Philipp Koch, who led the study together with Dr. Julia Ladewig.

«In this study, we showed that cancer stem cells co-opt a RNA editing system to clone themselves.