These include blood - derived leukocytes, cells of the mammary epithelium, stem cells and
cell fragments, which provide immune - protection to the infant.
(Patients may also receive infusions of white cells that help fight infection or platelets, the small, colorless
cell fragments that help stanch bleeding by clotting.)
Previous studies had shown that if you cut a Stentor cell in half,
each cell fragment will regenerate into a fully functional cell with a mouth and tail.
«The method we used involved the sequencing and quantification of RNA molecules in individual
cell fragments, something that was never done before,» says Dr. Thijs Ettema, associate professor at the Department of Cell and Molecular Biology, Uppsala University, who led the study.
New paper available: RNA sequencing of Stentor
cell fragments reveals key processes underlying cellular regeneration
As it also generates transcriptome data from separate Stentor
cell fragments, it paves the way for future investigations of transcriptional responses below the level of individual cells.
Our new study uses transcriptomics of
cell fragments of the ciliate Stentor to reveal the importance of protein phosphorylation, microtubule - based processes and genes involved in the cell cycle for cellular regeneration.
Red blood cells are recycled here; platelets (a small colorless disk - shaped
cell fragment without a nucleus, found in large numbers in blood and involved in clotting) and white blood cells (less technical term for leukocyte which include lymphocytes, granulocytes, monocytes, and macrophages) are stored in the spleen.
Casts are accumulations of
cell fragments and debris that built up in the small tubules that lead urine from its formation in the kidneys to its storage in your dog or cat's bladder.
Not exact matches
Sometimes these
fragments end up being reabsorbed by the embryonic
cells.
TruePrime LB addresses current liquid biopsy sensitivity and specificity issues by using adapted amplification of cancer - specific, large -
fragment,
cell - free DNA based on primer - free technology that combines the enzymes TthPrimPol and Phi29 DNA polymerase.
In Robinson's lab, Sharon studied protein - protein interactions within proteasomes, large multiprotein complexes that clear
cells of unwanted proteins by degrading them into small peptide
fragments.
In SIF - seq, hundreds or thousands of DNA
fragments to be tested for enhancer activity are coupled to a reporter gene and targeted into a single, reproducible site in embryonic
cell genomes.
Small protein
fragments, also called peptides, are promising as drugs because they can be designed for very specific functions inside living
cells.
The «bad» ApoE4 form tends to be broken down into toxic
fragments that damage the
cell's energy factories — the mitochondria — and alter the
cell skeleton.
In another study, Rezende helped functionally characterize the specific
fragments of the
cell surface protein, Als5p, that allows the pathogenic fungus, Candida albicans, to bind to its host.
The chromosomes here were isolated from
cells, heated until each DNA double helix unzipped into two complementary strands, and then mixed with previously prepared, tagged DNA
fragments.
Some lab tests have shown nano - sized plastic
fragments can enter
cells and cause tissue damage.
As those
cells proliferated in laboratory dishes, the bits of human DNA were also copied, creating
cell lines, each of which had a different
fragment.
In June, however, researchers reported evidence of blood
cells and collagen fibers in poor - quality fossil
fragments that were 75 million years old.
The task of HLAs is to bind to
fragments of proteins that are broken down in the
cells, transport the
fragments to the
cell surface and present them to the T - lymphocytes.
The presence of the dead, snarled nerve
cells and sticky protein
fragments characteristic of Alzheimer's in the main smell - processing structures of these deceased patients could suggest the disease gets its start in the olfactory system.
These improvements push the boundaries of nucleic - acid detection and
fragment sizing, affecting applications such as single -
cell nucleic acid analysis, PCR - free preparation of NGS library preparation, bacterial artificial chromosome clone sizing, and exosome analysis.
When the team used
fragments of interfering RNA to sabotage the production of beta - catenin in these stem
cells, the blood
cells returned to an early leukaemic state.
But additional research has confirmed that structures resembling blood
cells and collagen protein fibers — key elements of connective tissue — were preserved in six of eight
fragments.
The answer could lie in tiny
fragments of RNA that are passed on in sperm
cells.
«The gene has been cloned, and we know it interferes with the production of toxic amyloid
fragments,» says Ralph Nixon, a professor of psychiatry and
cell biology at New York University School of Medicine and a past chair of the Medical and Scientific Advisory Council of the Alzheimer's Association.
Neurobiologist Ulo Langel of Stockholm University in Sweden, with colleagues at several other labs, solved this problem by pairing PNAs with
fragments from two other proteins — transportan or pAntp — that use an unidentified mechanism to slip easily into
cells.
However,
fragments of viral DNA remain and are detected by the resting host
cell.
Aborted viral DNA
fragments are quickly removed during infection by
cell - free HIV particles, so they are not detected by the
cell's defensive system.
When prompted,
fragments of a tRNA synthetase come together and charge a tRNA with a bio-orthogonal amino acid (N3), which is inserted as a recognizable tag into all subsequent proteins made in the
cell.
However, in
cell - to -
cell transmission, the viral DNA
fragments overwhelm
cell maintenance, building up until they surpass a threshold and are detected.
They checked that the viral gene
fragments in the child and mother were a close match, and double - checked that the samples of blood
cells from the child were his and no one else's, by matching them genetically with the mother.
DCs are specialized immune
cells that can ingest foreign antigens, degrade them and present the
fragments on their surface to activate T
cell - mediated immunity.
There it passes on the
fragments to other immune
cells, which produce a distinctive fork - shaped antibody, known as immunoglobulin E, or IgE.
3) Protein binds to HIV
fragment on helper T
cell and CD3 receptor on killer T
cell, activating the killer T
cell and bringing the two
cells close together.
Desgrosellier said the team will follow up with mouse models containing tumor
fragments from patients to better reflect the diversity of
cell types present in human disease.
«Our hypothesis was that Lyme bacteria shed vesicle - like particles — or
fragments — derived from the
cell wall of the bacteria circulating in the serum of individuals.
By cutting gelsolin down to a specific
fragment and putting it into chemo - resistant cancer
cells, the international team discovered they could make these
cells susceptible to the cancer - killing effects of cisplatin.
Expression of the adiponectin gene was reduced in the offspring of sleep -
fragmented mothers, especially in their visceral fat
cells.
Neuronal
cell - glial
cell adhesion was inhibited by prior incubation of the neurons with Fab»
fragments of antibodies to neuronal membranes.
«The antigens must get far enough into the
cell for them to be processed, but must also return — as antigen
fragments — to the surface.»
It is the APCs which ingest antigen, break it down, combine the
fragments with Class II molecules, return them to the surface and «present» them to T
cells.
p53 activates a mitochondrial protease called Omi, which is then released into the cytosol of the
cell when Ras causes mitochondria to
fragment.
The method has allowed researchers to study key players involved in
cell division — which include proteins that form much of the structure of chromosomes, and
fragments of DNA that help to orchestrate the process.
Over time, formalin crosslinks proteins in the
cells, and
fragments and derivatizes both DNA and RNA.
The researchers also found differences in microRNA expression in bipolar
cells — tiny
fragments of RNA that play key roles in the «reading» of genes.
But rather than delivering the entire gene for the clotting - factor proteins to
cells, as most gene therapies do, the researchers used the viruses to engineer immune - regulating B
cells to express a
fragment of the clotting factor fused to an immune molecule called an immunoglobulin.
Following a single treatment with CRISPR / Cas9, viral
fragments were successfully excised from latently infected human
cells embedded in mouse tissues and organs.
If it was a mixture of microbes, it would be the perfect sample for a technique she and her colleagues were developing called Hi - C sequencing, which disentangles the genomic sequences of a community of microbe species using formaldehyde to link DNA
fragments within the same
cell.