Specifically, intensive postmortem neurological
studies of their brain tissues reveal a relatively low density of acetylcholine (a neurotransmitter) nerve sites, which, at normal densities, function in critical ways to help re-initiate breathing following a sleep - related apnea or extended breathing pauses.
Not exact matches
More work has to be done on humans as many
of the results showed up in mice samples, however in
studying the human
brains of women who had AD scientists found significantly less male fetal
tissue in their
brains as in the same
of women who did not have AD.
It's to put the
study of the mind back in the
study of the
brain, says Solms: «What neuropsychoanalysis is all about is this: How does the actual stuff
of being a person relate to the
tissue and physiology and anatomy and chemistry
of the
brain?»
Kristian Doyle, assistant professor
of immunobiology and neurology at the University
of Arizona College
of Medicine in Tucson, uses biomarkers to
study how the immune system deals with dead
brain tissue after a stroke.
As another crucial part
of the new
study on Internet addiction, the research team zeroed in on
tissue deep in the
brain called white matter, which links together its various regions.
Focusing on the neural pathway from the
brain's prefrontal cortex to the amygdala, they combined optogenetics — a technique that uses light to control the activity
of neurons in living
tissue — with behavioral testing, a methodology that allows researchers to
study functional connections between different regions
of the
brain.
In the new
study, researchers mined databases
of genomic data from humans and chimpanzees, to find enhancers expressed primarily in the
brain tissue and early in development.
A recent
study published in Annals
of Neurology reports that healthy human
tissue grafted to the
brains of patients with Huntington's disease in the hopes
of treating the neurological disorder also developed signs
of the illness, several years after the graft.
Among the 42 Zika - infected women in the
study, 12 were carrying fetuses with severe abnormalities, including absence or withering
of brain structures,
tissue death, restricted growth and, in one case, microcephaly.
Twenty people in the
study experienced meningitis (inflammation
of the
tissue that surrounds the
brain and spinal cord), either while they were being treated for Ebola or after they left the treatment unit.
Now, researchers in The Netherlands have coupled machine learning methods with a special MRI technique that measures the perfusion, or
tissue absorption rate,
of blood throughout the
brain to detect early forms
of dementia, such as mild cognitive impairment (MCI), according to a new
study published online in the journal Radiology.
The findings tallied with another
study which involved screening post-mortem
brain tissue from people who had had some form
of psychosis.
Recent
studies suggest that the total loss in
brain volume due to atrophy — a wasting away
of tissue caused by cell degeneration — between our teen years and old age is 15 percent or more, which means that by the time we're in our seventies, our
brains have shrunk to the size they were when we were between 2 and 3 years old.
Dr Vera Weisbecker
of UQ's School
of Biological Sciences said the
study represented the first dataset comparing
brain growth in different mammals, gathered through a novel method
of non-invasive micro-CT (computed tomography) scanning which allowed the fast data acquisition
of soft
tissue growth in tiny mammals.
Mammalian
brain growth is
studied in this paper which shows that a widely accepted hypothesis
of how the mammalian
brain proportions grow and evolve does not work, using a novel method
of micro-CT scan that allows the first fast data acquisition
of soft
tissue growth in tiny mammals.
Researchers also
studied the
brain tissue of the infected mice under a microscope and found that the memory problems tracked with changes in nerve cells.
«Zebrafish
brain repair following concussion: New model enables
study of animal's remarkable ability to regenerate injured
brain tissue.»
In this
study, the researchers from Imperial's Department
of Surgery and Cancer and the Royal British Legion Centre for Blast Injury
Studies, applied xenon to slices
of mouse
brain tissue after exposing them to blast shockwaves that emulated those produced by improvised explosive devices (IEDs).
Again, McAninch and colleagues also continued to collaborate with the University
of Miami
Brain Bank to obtain and study brain tissue from young, healthy African American brain do
Brain Bank to obtain and
study brain tissue from young, healthy African American brain do
brain tissue from young, healthy African American
brain do
brain donors.
Powers is planning expand his
study size and is partnering with another CCTS - funded stroke investigator who developed an animal model
of ischemia in order to analyze micro-RNA released in
brain tissues at the precise area around a blocked blood vessel.
Researchers most commonly
study the effect
of antidepressants using a technique known as microdialysis, in which they insert a probe into the
brain to take tiny chemical samples from the
tissue.
The cerebral cortex is the outermost layer
of neural
tissue in the
brain and is one
of the most extensively
studied brain structures in the field
of neuroscience.
A weakness
of the
study is that it does not include any measured observations
of the
brain tissue, which is often the case in
studies of Alzheimer's disease.
In this
study, the researchers looked at the organization
of newborn
brain tissue using Diffusion Tensor Imaging (DTI), a magnetic resonance imaging (MRI) technique.
The
study shows that one out
of three stroke patients who present with at - risk
brain tissue on their scans improve and some may walk out
of the hospital saved from what would otherwise have been a devastating
brain injury.»
A September 2002 follow - up
study found no evidence for widespread transdifferentiation
of blood - forming stem cells in
brain, liver, kidney, gut and other
tissues.
«Only about half
of the patients we screened with the
brain - imaging software had enough salvageable
brain tissue to enter the
study.
In the 8 participants for whom an adequate number
of imaging
studies were completed, whole
brain volume — the overall amount
of brain tissue — decreased significantly throughout the
study period.
Historically, animal models — from fruit flies to mice — have been the go - to technique to
study the biological consequences
of aging, especially in
tissues that can't be easily sampled from living humans, like the
brain.
Doing this type
of study on cells in
brain tissue has been challenging because the cells are densely packed and intimately intertwined.
Importantly, individual classes
of inhibitory neurons are quite sparse in the
brain, so any unique features
of those cells would likely have been lost in earlier
studies that looked at the
tissue as a whole.
Working with the
brains of six normal children and seven autistic children ages 2 to 16, most
of whom died
of drowning, Courchesne has
studied neurons under the microscope and even counted the number
of neural cells in different
tissue samples.
A recent generation
of studies of postmortem
brain tissue from people with schizophrenia, particularly from the laboratory
of Professor David Lewis and his colleagues at the University
of Pittsburgh, have shed light on schizophrenia - related abnormalities in the interplay
of the main excitatory neurons, pyramidal neurons, and a specific class
of inhibitory nerve cells, called chandelier cells, in the prefrontal cortex.
The
study of human astrocytes has faced issues related to access (samples
of living
tissue must be obtained from
brain cancer or epilepsy surgeries or fetal
tissue) and purification (breaking apart astrocytes away from other cells often killed them and many experiments ended in failure).
The 3D
tissue structures will let researchers
study the early stages
of human
brain development in unprecedented detail.
«It's critically important to be able to look at questions
of brain development in real human
tissue when you're trying to
study human disease.
But metal electrodes can quickly damage natural
brain tissue, making it impossible to
study the transfer
of signals over extended periods.
In a
study published in the Journal
of Clinical Investigation, researchers looked at how immune cells reached the myelin, focusing on the barrier between
brain tissue and the rest
of the body.
The researchers conducted additional
studies of the virus using
brain tissue from epilepsy patients and showed that the virus does not infect noncancerous
brain cells.
Here at the Harvard
Brain Tissue Resource Center, donated specimens are sliced up, preserved, stored, and eventually parceled out to neuroscientists worldwide who
study them for clues to disease, cognition, and the mysterious cellular underpinnings
of psychology.
Thousands
of studies have suggested that stimulating
brain tissue like this can help treat a range
of conditions including tinnitus, depression and stroke.
«We are talking about fast - growing tumors that invade normal
brain tissue and are very difficult to treat,» said Orin Bloch, MD, a neurosurgeon at Northwestern Memorial Hospital and lead author
of the
study.
If the compound identified in this
study successfully reduces
tissue death and improves recovery in further experiments, it could lead to new approaches for preserving
brain cells after an ischemic stroke,» said Francesca Bosetti, Ph.D., Pharm.D., program director at the NIH's National Institute
of Neurological Disorders and Stroke (NINDS).
Interestingly, many
of the genes identified in this
study have been shown to have lower gene activity at the molecular level in autistic post mortem
brain tissue samples.
Studies have found beta - amyloid in
tissue following traumatic
brain injury and as evidence
of optic nerve damage in shaken - baby syndrome.
Joanna Fowler has made significant contributions to
brain research and the understanding
of diseases such as addiction, which she
studies using positron emission tomography (PET), an imaging technique that measures the concentration and movement
of a positron - emitting radioisotope in living
tissue.
Changiz Geula, a professor
of neuroscience at Northwestern University, has been
studying brain tissue collected from people who died at age 90 or older.
The
study published in the Journal
of Alzheimer's Disease focused on a type
of brain tissue called white matter, which is composed
of millions
of bundles
of nerve fibers used by neurons to communicate across the
brain.
In their comprehensive
study, which involved a search
of gene activity maps as well as testing
of human
brain tissue, the researchers identified more than 100 enhancers which were much more active in the
brain than in other
tissues.
For the moment, Blue
Brain scientists study rodent brain tissue and characterize different types of neurons to excruciating detail, recording their electrical properties, shapes, sizes, and how they con
Brain scientists
study rodent
brain tissue and characterize different types of neurons to excruciating detail, recording their electrical properties, shapes, sizes, and how they con
brain tissue and characterize different types
of neurons to excruciating detail, recording their electrical properties, shapes, sizes, and how they connect.