Sentences with phrase «studies of the haplotype»

Not exact matches

Indeed, he notes, it's improbable that all of the previous genetic studies of red deer, including those living throughout Europe today, wouldn't have picked up any of the haplotypes he and his team identified in their new research.

«For instance, the benefits of the new UK10K haplotype reference panel are already being realised in analyses of international consortia as well as the 0.5 M people UK BioBank study.»

Apart from a few private Northern European haplotypes, all modern horse breeds included in the study clustered into a roughly 700 - year - old haplogroup, transmitted to Europe by the import of Oriental stallions, they report.

The research team, co-led by Dr Rollins and Professor Bill Sherwin of UNSW, in collaboration with the Department of Agriculture and Food in Western Australia, studied the DNA of 279 starlings near Munglinup in the south east of Western Australia and identified birds with a novel mitochondrial genome sequence (Haplotype H).

To study natural selection, the team combed the International Haplotype Map for long stretches of DNA flanked by a single nucleotide polymorphism (SNP, or «snip»)-- that is, an altered base, or «letter,» in the genetic alphabet.

Professor Sherwin, of the UNSW School of Biological, Earth and Environmental Sciences, said the advantageous mutation then spread rapidly through the population, with the proportion of birds carrying Haplotype H increasing from 17 per cent to 47 per cent during the five years of the study.

In the study, researchers applied the pipeline to sequence the genome of an Asian individual (YH) and generated a 5.15 Gb assembled genome with a haplotype N50 of 484 kb.

Omics techniques employed in our group range from whole genome sequencing and epigenomic techniques, to single cell / single strand DNA sequencing (Strand - seq; see Figure 1), the latter of which enables haplotype - resolved studies of genetic variation and genome instability.

Individuals with APOE 3 — TOMM40 clade A haplotypes had a mean AAO of 73.31 years vs 72.93 years for APOE 3 — TOMM40 clade B. Thus, in this much larger study (total cases = 1594, total controls = 1190; total APOE 33 cases = 474, total APOE 33 controls = 701) than the original study (N = 34), we found a trend toward association but in the opposite direction than previously reported.

September 23, 2003 deCODE has identified both at - risk and pretective haplotypes within the PDE4D gene, and is applying its findings to develop novel drugs and diagnostics deCODE's landmark study in the genetics of stroke, identifying the first gene ever linked to...

Polymorphisms in five of 15 genes (33 %) encoding molecules known to primarily influence pancreatic beta - cell function - ABCC8 (sulphonylurea receptor), KCNJ11 (KIR6.2), SLC2A2 (GLUT2), HNF4A (HNF4alpha), and INS (insulin)- significantly altered disease risk, and in three genes, the risk allele, haplotype, or both had a biologically consistent effect on a relevant physiological trait in the QT study.

200/3: 30 Imputing genotypes of the Haplotype Reference Consortium into the haplotypes of a large case control study of age - related macular degeneration.