Dr. Christiane Opitz —
Studying cancer cell metabolism, treating terminally ill patients, pursuing an academic career and enjoying motherhood.
Not exact matches
Middle - aged people who eat protein - heavy diets are four times as likely to die of
cancer as those who eat only a little protein, according to the
study, which was published in the journal
Cell Metabolism.
Contrary to current research this new
study found that LKB1, a molecule that regulates the
metabolism of many adult
cells, is an important molecule in the
cancer's promotion and survival.
This suggests that «the python intestine may represent a valuable model for
studying the interactions of
metabolism with the regulation of
cell division / death and WNT signaling relevant to
cancer,» the researchers said.
Frigo and his team demonstrated in this
study that androgens take control of the AMPK signaling cascade, a master regulator of
metabolism, to increase prostate
cancer cell growth.
In a
study presented in the featured clinical investigation article of the November issue of The Journal of Nuclear Medicine, they used 18F - fluorodeoxyglucose (FDG) PET / CT imaging to show that the amount of
cell - free tumor DNA circulating in the bloodstream correlates with tumor
metabolism (linked to
cancer aggressiveness), not tumor burden (amount of
cancer in the body).
After completing her graduate
studies in 2006, she joined the laboratory of Dr. Craig B. Thompson at the University of Pennsylvania for postdoctoral work focusing on
cancer cell metabolism.
Lee believes that the
study findings provide additional insight about the «crosstalk» between
cancer metabolism and
cell cycle.
To address these questions, Dang, Altman, and Hsieh collaborated with Penn colleague, Aalim Weljie, PhD, research assistant professor of Pharmacology, using an osteosarcoma
cancer cell line to
study the interaction of MYC and
metabolism in
cancer cells.
«This work ties together the
study of
cell metabolism and
cancer chronotherapy — If
cells don't have to «rest,» they may replicate all the time, with no breaks at all.»
«Our original hypothesis was that
cancer cells were modifying their
metabolism based on communications they were receiving from
cells in the microenvironment near the tumor,» said Nagrath, assistant professor of chemical and biomolecular engineering at Rice and co-author of a new
study describing the research in the open - access journal eLife.
«Some
studies suggested that exosomes harbored the potential to regulate
cancer cell metabolism, but most research had focused on the exosomes that were produced and emitted by
cancer cells themselves.
If you read some of the published
studies from Dr. Seyfried and Dr. D'Agostino, you'll see that they are working on the idea of combining this kind of therapeutic ketosis with other supplements that challenge
cancer cell metabolism.
A 2015
study in mice, published in the journal
Cell Metabolism, found that following a calorie - restricted diet that mimics fasting for five days a month for three months may promote a longer life and also reduce the risk factors for a number of conditions, including certain
cancers, diabetes, and heart disease.
In 1931 Otto Heinrich Warburg was awarded the Nobel Prize in Physiology for his
study on the
metabolism of tumors and the respiration of
cells, particularly
cancer cells.
This is a link to another recent
Cell Metabolism study publication that looked at actual people as opposed to mice - Low Protein Intake Is Associated with a Major Reduction in IGF 1,
Cancer, and Overall Mortality in the 65 and Younger but Not Older Population
Cell Metabolism, Volume 19, Issue 3, 407 - 417, 4 March 2014
Because
cancer cell metabolism relies upon glucose, minimizing a tumor's access to sugar as a means to manage or even limit cancerous
cell growth has been the subject of several recent
cancer therapy
studies.