Studying simian immunodeficiency virus (SIV), the team found that specialized cells in the intestine called Paneth cells are early responders to viral invasion and are the source of gut inflammation by producing a cytokine called interleukin - 1 beta (IL - 1β).
Not exact matches
To
study the pathogenesis of HIV - induced PNS disease, Jamie Dorsey, Research Technologist, and the research team led by Dr. Mankowski developed a
simian immunodeficiency virus (SIV)- infected macaque model that closely reflects key peripheral nervous system (PNS) alterations seen in HIV patients with peripheral neuropathy.
Researchers for the past decade have focused on the T cell approach, based on
studies showing that monkeys receiving such vaccines against
simian immunodeficiency virus, related to HIV, lived longer or had lower viral levels than usual.
And in a
study of monkeys, researchers discovered that a cytomegalovirus - based vaccine protected 50 percent of animals from infection by
simian immunodeficiency virus.
HIV's close cousin, the
simian immunodeficiency virus (SIV), has been around for tens of thousands of years — much longer than the few hundred years that some
studies had suggested.
In April two
studies of
simian immunodeficiency virus, a kin of HIV that infects monkeys, reported that the virus swiftly infects and decimates key immune cells in the gut within days, not years, of infection.
A new
study led by scientists at Beth Israel Deaconess Medical Center (BIDMC) shows that an HIV - 1 vaccine regimen, involving a viral vector boosted with a purified envelope protein, provided complete protection in half of the vaccinated non-human primates (NHPs) against a series of six repeated challenges with
simian immunodeficiency virus (SIV), a virus similar to HIV that infects NHPs.
A new
study, published in PLOS Pathogens, investigates the genome editing of bone - morrow stem cells in pigtail macaques as a potential treatment for
simian / human
immunodeficiency virus (SHIV).
Results from a recent
study show that novel vaccine combinations can provide partial protection against infection by
Simian Immunodeficiency Virus (SIV) in rhesus monkeys.