Sentences with phrase «studying the diseased cells»

For many illnesses, researchers would like to study the diseased cells from a patient in the lab; their ultimate hope is that they can also fix those cells by modifying them genetically and then inject them back into the patient.

Studying the diseased cells in a controlled environment allows scientists to test environmental factors and drugs on the cells, while also gaining insight into how the neurons develop defects or dysfunction.

Not exact matches

A stronger immune system: Another study found that taking daily cold showers increases the number of disease - fighting white blood cells.

The biotech specialist said that its updated phase 2 data in a study of its poziotinib candidate treatment for non-small cell lung cancer resulted in a preliminary confirmed objective response rate and potential progression - free survival benefit in patients with the EGFR Exon 20 Mutant form of the disease.

Studies have shown that their wide array of antioxidants actually inhibit the growth of cancer cells, as well as protecting the body from cardiovascular disease — orange vegetables have been shown to provide the most protection against this disease.

It offers cardio protection, it helps lower bad cholesterol, it may help prevent the progression of multiple sclerosis, it has the ability to regenerate brain cells after a stroke, it has the ability to cross the blood - brain barrier to potentially ward off Alzheimer's disease, apparently it's good at wiping amyloid plaque from the brain (which studies haves linked to Alzheimer's), it may help to prevent certain types of cancer, and studies have shown that it inhibits cancer cell growth and metastases (meaning it keeps cancer from spreading).

One study, published in the «Journal of Alzheimer's Disease» in October 2013, found that the oil in coconut helps shield nerve cells from the toxic effects of protein plaques, which would otherwise drive Alzheimer's disease progrDisease» in October 2013, found that the oil in coconut helps shield nerve cells from the toxic effects of protein plaques, which would otherwise drive Alzheimer's disease progrdisease progression.

This article is questionable as it has no links or actual references to the studies it talks about, like someone above has mentioned also there is no information on how the diagnosis were made, and lastly it does not take into account that celiac disease is NOT an allergy, it is an auto immune disease where the body attacks its own cells confusing them with gluten proteins, it is not about tolerance, I would not be trusting this information, do lots of research on your own from legitimate scientific sources before making a decision.

«By studying the ways different proteins like keratin dynamically change within a cell, we can better understand the progression of cancers and other diseases,» they say.

Cadwell cautions that such a strategy must await further evidence to confirm his theory that this trend in Paneth cell death occurs in people deficient in ATG16L1 who are, like his study mice, prone to higher risk of inflammatory disease and transplant rejection.

«Our study results are the first to argue that we may be able to treat inflammatory bowel disease and protect against transplant rejection not only by blocking TNF alpha as is done currently, but also by stimulating ATG16L1 to prevent early death of cells lining the gut,» says study senior investigator Ken Cadwell, PhD, an associate professor at NYU School of Medicine and NYU Langone Health's Skirball Institute for Biomolecular Medicine.

McCallion's strategy to make sense of all this data looks at the active genes in cells affected by a disease, groups of genes that interact with one another, their vulnerability to mutation and information from past scientific studies to filter more than a thousand gene candidates for disease risk down to just a handful within any one implicated region.

A related paper, involving Svendsen, his colleague Gad Vatine, PhD, and a team from University of California, Irvine, published the same day in the journal Cell Reports, used a similar approach to study Huntington's disease.

In a study, his team found that female incest survivors had abnormalities in the ratios of immune cells, compared with untraumatised women, exposing them to autoimmune diseases.

In the present study, the researchers have discovered a reason for reduced fertility in people with autoimmune polyendocrine syndrome type 1 (APS1), which increases the risk of developing autoimmune disease (caused by the immune system attacking and damaging healthy cells) and which is often used as a model for autoimmune disease in general.

The diagnosis of cancer and study of disease progression is often accomplished by examining a tumor sample containing many billions or even trillions of cells.

Workers in Chinese factories exposed to high levels of formaldehyde had lower counts of white blood cells that fight germs and diseases, according to a 2010 study led by Zhang.

«Chronic inflammation of the intestine is thought to be caused by abnormal interactions between gut microbes, intestinal epithelial cells and the immune system, but so far it has been impossible to determine how each of these factors contribute to the development of intestinal bowel disease,» said Hyun Jung Kim, Ph.D., former Wyss Technology Development Fellow and first author on the study, speaking about the limitations of conventional in vitro and animal models of bacterial overgrowth and inflammation of the intestines.

Scientists use cell reprogramming techniques to produce cells in the lab so that they can study diseases.

In a groundbreaking study that provides scientists with a critical new understanding of stem cell development and its role in disease, UCLA researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research led by Dr. Kathrin Plath, professor of biological chemistry, have established a first - of - its - kind methodology that defines the unique stages by which specialized cells are reprogrammed into stem cells that resemble those found in the embcell development and its role in disease, UCLA researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research led by Dr. Kathrin Plath, professor of biological chemistry, have established a first - of - its - kind methodology that defines the unique stages by which specialized cells are reprogrammed into stem cells that resemble those found in the embCell Research led by Dr. Kathrin Plath, professor of biological chemistry, have established a first - of - its - kind methodology that defines the unique stages by which specialized cells are reprogrammed into stem cells that resemble those found in the embryo.

Scientists have made a key discovery that could speed up the production of cells in the lab for studying diseases such as multiple sclerosis and Parkinson's disease.

What impact they may have had is now only a guess, but this study revealed that these cells were less common in the brains of women who had Alzheimer's disease, suggesting they may be related to the health of the brain.

«Cultural revolution in the study of the gut microbiome: Human gut - on - a-chip technology used to co-culture gut microbiome, human intestinal cells could lead to new therapies for inflammatory bowel diseases.»

Today in Cell and associated journals, 24 research studies from the landmark BLUEPRINT project and IHEC consortia reveal how variation in blood cells» characteristics and numbers can affect a person's risk of developing complex diseases such as heart disease, and autoimmune diseases including rheumatoid arthritis, asthma, celiac disease and type 1 diabetes.

In preclinical studies using cell models that mimicked liver cells of patients with the rare disease Friedreich's ataxia (FA), a widely used cholesterol - lowering drug increased a precursor of HDL (high - density lipoprotein), the «good cholesterol,» according to new research published in PLOS ONE from the Perelman School of Medicine at the University of Pennsylvania.

The idea to specifically study this group of patients was based on groundbreaking research Garon published in the New England Journal of Medicine last year, which found that among patients who received pembrolizumab, those with PD - L1 expression on at least 50 percent of their cancer cells showed the longest survival and disease control.

«Mechanistic finding may help develop treatment for Ice Bucket Challenge disease: Study blames a fault in the cell's machine that cuts and pastes genetic instructions for a deadly motor neuron disease.»

«We found that a particular vaginal bacterium, Gardnerella vaginalis, did not cause infection during exposure to the urinary tract, but it damaged the cells on the surface of the bladder and caused E. coli from a previous UTI to start multiplying, leading to another bout of disease,» said the study's senior author, Amanda Lewis, PhD, an assistant professor of molecular microbiology and of obstetrics and gynecology at Washington University.

Yang said the study not only indicated which genes are affected by traumatic brain injury and linked to serious disease, but also might point to the genes that govern metabolism, cell communication and inflammation — which might make them the best targets for new treatments for brain disorders.

Guo and his collaborators continue their studies by establishing additional mouse models of leukemia that have been transplanted with patient cells of relapsed and refractory disease.

Dr. McCabe said nanoparticles are a leading - edge technology also being studied for delivery of drugs for other conditions, such as cancer, heart disease, and bacterial infections, in order to target specific cells to reduce toxicity and side effects of those medications and to make them more effective.

Researchers at Nagoya University have been studying the therapeutic effect of T cells, vital disease - fighting components in our body's immune system, for fighting cancer.

We believe that they will also lead to the development of a whole new range of therapies for neurodegenerative diseases of the central nervous system,» explains corresponding author of the study Jihwan Song, professor and director of Neural Regeneration and Therapy Group at the CHA Stem Cell Institute of CHA University.

This proof - of - principle study shows «for the first time... that human iPS cells can be used to model a diverse range of inherited diseases in adult cells,» the authors wrote in their paper, published online in The Journal of Clinical Investigation August 25.

A new study has found that stem cell therapy can reduce lung inflammation in an animal model of chronic obstructive pulmonary disease (COPD) and cystic fibrosis.

«Our studies show that mutations in our white blood cell cells, that we acquire as we age, may cause cardiovascular disease.

Tissue engineering provides a more practical means for researchers to study cell behavior, such as cancer cell resistance to therapy, and test new drugs or combinations of drugs to treat many diseases.

Specifically, the Mount Sinai study was designed to test whether pharmacological compounds designed to block the function of XPO1 / CRM1 could stop disease progression in mouse models that exhibit some of the characteristics of MS. Researchers found that two chemical agents (called KPT - 276 and KPT - 350) prevented XPO1 / CRM1 from shuttling cargo out of the nucleus of nerve cells, which protected them from free radicals and structural damage.

In addition, the substance used to stick cells together (ViaGlue), will provide researchers with tools to create and test 3D in vitro cardiac tissue in their own labs to study heart disease and issues with transplantation.

Now, a UCLA study has traced the Pavlovian response to a small cluster of brain cells — the same neurons that go awry during Huntington's disease, Parkinson's disease and Tourette's syndrome.

Together, the two studies advance the idea that gut microbes play a role in turning the immune system against nerve cells, causing MS.. It will take a lot more work to develop cures or preventive strategies based on that, but the research raises the intriguing possibility of treating an often - devastating disease with something as low - tech as fecal transplants or probiotics.

The study involved laboratory cell lines of human leukemia and mouse models of the disease.

Comparing his study to Surmeier's, Redmond noted: «One is an approach to try to minimize disease progression or maybe even get some recovery, the other is more aimed at the other end, after (dopamine - producing] cells are already dead.»

Mice transplanted with cells grown from a patient suffering from Huntington's disease (HD) develop the clinical features and brain pathology of that patient, suggests a study published in the latest issue of Acta Neuropathologica by CHA University in Korea, in collaboration with researchers at Université Laval in Québec City, Canada.

Studying such diseases is a good first step because they are cancers of immune cells themselves, and it's possible to analyze them with a mere blood sample.

In research that has implications for diabetes and other metabolic diseases, an international study based at UT Southwestern Medical Center found that the protein connexin 43 (Cx43) forms cell - to - cell communication channels on the surface of emerging beige fat cells that amplify the signals from those few nerve fibers.

The study successfully countered harmful effects of mutant huntingtin and protected nerve cells in several models of Huntington's disease.

«The compounds identified in this study, when administered orally, both reduced the inflammation that is a hallmark of multiple sclerosis and protected against the nerve cell damage seen in mouse models of the disease,» said Jeffery Haines, PhD, a post-doctoral fellow at Mount Sinai and the study's lead author.

But a new study suggests that mature cells also play a key role in initiating cancer — a finding that could upend the way scientists think about the origins of the disease.

A study has traced the Pavlovian response to a small cluster of brain cells — the same neurons that go awry during Huntington's disease, Parkinson's disease and Tourette's syndrome.