Sentences with phrase «studying these models allowed»

Studying these models allowed us to see for the first time how a specific genetic mutation may kick start the tauopathy process.»

Studying these models allowed the research team to see how the LRRK2 mutation kick starts neurodegeneration — making this an extremely powerful model of Parkinson's disease.

Not exact matches

The complaint may be that the curriculum is too «academic» and insufficiently «Professional»; too «theoretical» and insufficiently «practical»; or, conversely, that it is too single - mindedly focused on producing «Professional ministers» in a certain model and too inflexible to allow individual students to pursue their own intellectual interests; and, above all, that the curriculum consists of too many small pieces of information that are not adequately «integrated,» that it provides not so much a course of study as — in H. Richard Niebuhr's wonderfully wry phrase - «a series of studious jumps in various directions.»

In this theoretical model, the OIST researchers believe they have found a way to create a stable necklace, one that would allow for more time to study it and appreciate its refined majesty.

Researchers from Instituto de Medicina Molecular (iMM) Lisboa have created a chimera virus that allows the study of molecules to treat cancers caused by human herpes virus infection in mice models of disease.

«Advances in high performance computing are finally allowing us to understand the explosive death of stars, and this study shows that such models are needed to figure out new ways to measure dark energy.»

«This study is important, in part because we now have a new xenograft model that will for the first time allow us to apply new biomarkers to better predict disease progression and test new therapeutics.»

Satellite imagery is used for all sorts of climate study, from identifying conditions that allow infectious diseases like West Nile virus and cholera to emerge, to creating models for predicting hurricanes, to distinguishing natural resources such as wind, water and sunlight.

But the fact that one part of the rings didn't cool as expected allowed us to model what they might be like on the inside,» said Ryuji Morishima of NASA's Jet Propulsion Laboratory, Pasadena, California, who led the study.

These techniques include: human tissue created by reprogramming cells from people with the relevant disease (dubbed «patient in a dish»); «body on a chip» devices, where human tissue samples on a silicon chip are linked by a circulating blood substitute; many computer modelling approaches, such as virtual organs, virtual patients and virtual clinical trials; and microdosing studies, where tiny doses of drugs given to volunteers allow scientists to study their metabolism in humans, safely and with unsurpassed accuracy.

«With this breakthrough it is possible to generate cell models with the same alterations as observed in tumour cells from patients, which will allow us to study their role in tumour development,» says CNIO researcher Sandra Rodríguez - Perales.

Using these models, we get a global view of the entire molecule and they also allow us to study changes in large proteins using a laptop in only a few minutes,» explains Orellana.

In addition to helping understand disease by providing more powerful study models, «what this technology would allow you to do is reprogram a skin cell, for example, from a Parkinson's patient... into a pluripotent cell and then in a petri dish redirect that cell into... a neuron» to treat that patient.

This new technology offers two main advantages based on the use of molecular tools to manipulate the genome: firstly, working models that had not existed up until now for the study of tumour biology and, secondly, their application will eventually allow for the study of new therapeutic targets and therapies.

Modeling studies on geoengineering to reflect sunlight away from the Earth suggest that modifying the planet's reflectivity could slow the meltdown of the Greenland ice sheet in the short term, but not stop it entirely, and could still allow an eventual total meltdown in the next millennia or so.

«For instance, a paper talking about protein - folding patterns is a great example of the practice of making models to understand phenomena, while preliminary results from a study of black holes might be a great way to ask students to examine what the next steps would be for the researchers, allowing them to develop hypotheses and design possible experiments,» Lake said.

Now, a team of scientists at the Icahn School of Medicine at Mount Sinai have developed the Just EGFP Death - Inducing T - cell, or JEDI T - cells, which enable the visualization of T - cell antigens, allowing researchers to study T - cell interactions with different cell types, model disease states, and finally determine the functions of otherwise poorly characterized cell populations.

«The nature of this research allows us to study the mechanisms of injury and recovery directly in humans rather than in animal models,» Dr. McCrea said.

The models were built and simulated using an open - source software package, EpiModel, that allowed the study authors to test different potential scenarios with varying levels of adherence to PrEP's recommended daily regimen and PrEP coverage among MSM.

«Studying these effects in model systems such as rats and flies allows us to address these questions by manipulating the likely mechanisms involved, which we can't do in humans.»

Mouse embryonic stem cells, reported in 1981 by Martin Evans, Matthew Kaufman, and Gail Martin, have allowed scientists to generate genetically customized strains of mice that have revolutionized studies of organismic development and immunity and have provided countless models of human disease.

The study also allowed the researchers to examine tree mortality — information needed to figure out how much carbon dioxide trees can store — to improve climate models.

Mitchell's current analysis covered studies involving a different mouse model that did allow for the observation of p - tau.

Mitchell's prior analysis examined lab studies that used an Alzheimer's lab mouse model that did not allow for the study of p - tau.

A new study using complex computational models finds that smart solid - state transformers (SSTs) could be used to make a stable, reliable «smart grid» — allowing the power distribution system to route renewable energy from homes and businesses into the power grid.

«The models fill important data gaps and allow relevant LCA studies to be carried out on electric powertrains.

«Models such as this allow us to study the focal system with almost no constraint of time or space, and explore a wide range of environmental conditions with a level of detail that can not be attained in the field.»

The 3D model allows surgeons to study the patient's specific defect in detail from every angle.

Modelling studies suggest that around Llyn Brianne reductions of between 30 and 50 per cent in the acidity of rainfall will be necessary to prevent further acidification of soils and streams and only a 60 to 90 per cent reduction would allow recovery of fisheries, river invertebrates and fishing birds such as dippers.

Using models and satellites The study authors» «cutting - edge methodology will allow observations to be used consistently to examine large - scale deforestation impacts on rainfall, and to refine and evaluate current models to support conservation planning in the tropics,» Aragao wrote.

However, using digital models has further advantages adds Dr. Lawrence Witmer: «Digital models allow the study of the external and internal features of a fossil.

«We have successfully developed the first mouse model for Alix that allows us to study the consequences of Alix loss of function in vivo.

In a new study, published online June 6 in Nature, researchers at University of California San Diego School of Medicine and Moores Cancer Center, together with colleagues at Keio University, the University of Nebraska and Ionis Pharmaceuticals describe an innovative new model that not only allowed them to track drug resistance in vivo, but also revealed a new therapeutic target, which early testing suggests could provide a strategy to arrest pancreatic cancer growth.

To study this barrier and determine why a lack of blood flow causes it to leak, the researchers built a blood - vessel - on - a-chip model consisting of a channel lined with a layer of human endothelial cells surrounded by extracellular matrix within a microfluidic device, which allowed them to easily simulate and control the flow of blood through a vessel and evaluate the cells» responses.

The screening procedure — used in the U.S. to model and study virus replication — allows for continuing evaluation of new antivirals or anti-Ebola drugs, since there is a likelihood of future Ebola outbreaks.

«The study provides more realistic modeling estimates of how much vegetation change will occur over the 21st century and will allow better predictions of future climate change,» she said.

«Future studies on maternal smoking and other environmental, genetic, and epigenetic factors, as well as animal models, should allow identification of the biological mechanisms responsible for these associations.

«We use zebrafish to study Alagille syndrome because these vertebrates allow us to use experimental approaches that aren't possible with other disease models,» says Duc Dong, Ph.D., assistant professor in the Human Genetics Program at SBP and senior author of the paper.

The results so far show only a correlation between fires and water cycle indicators, but the data gathered from the study is allowing scientists to improve climate models to be able to establish a more direct relationship between biomass burning and its impacts on drought.

«In this study, the Fluvial Egg Drift Simulator (FluEgg) model allowed us to examine the complex dependencies between flow, temperature, and egg development,» said USGS hydrologist Ryan Jackson.

For example, Chemistry - Climate models allow the possible effects of climate change on the recovery of the ozone hole to be studied.

The model allowed them to study the problem in greater detail, breaking the area into 12 - kilometer squares.

Medaka fish are considered model organisms for life science research, which means they have characteristics that allow them easily to be maintained, reproduced and studied.

A new study in animal models suggests that blocking a protein that helps the virus thrive could restore immune function, allowing the body to fight infection.

Physiological similarities between dogs and humans, and conserved genetics between some dog and human cancers, can allow pet dogs to serve as useful models for studying new cancer drugs, he said.

The introduction of fluid pressure modeling of both industry activity and water table fluctuations in the Azle study represents the first of its kind, and has allowed the SMU team to move beyond assessment of possible causes to the most likely cause identified in this report.

A nonhuman primate model could eliminate the current gap and allow researchers to better study aspects of fine motor control and cognition in a nervous system that is structurally similar to humans».

«Because the mice used in this model have immune systems that allow them to survive initial infection, they could be particularly helpful for studying the long - term effects of Zika virus infection.»

Further, future studies will take advantage of the induced non-human primate animal model of endometriosis allowing for the measurement of microbial changes throughout disease progression.

Main sequence stars have been extensively studied through stellar models, allowing their formation and evolutionary history to be relatively well understood.