Subgroup analyses showed that the prevalence of depression and depressive symptoms in different specialties varied from 17.0 % to 53.0 %.
Subgroup analyses showed significant differences for continent of residence and depression severity (ie, depressive symptoms or a clinical diagnosis depression).
Subgroup analyses showed trends or significant overall survival improvements for all subgroups measured, including by disease stage, ECOG score, age, and other factors.
Subgroup analyses showed benefit with the combination in all groups, with the exception of those with brain metastases at baseline, though this included a total of only 12 patients.
Commenting on the findings, Prof Robert Pirker, programme director for lung cancer at the Vienna General Hospital in Vienna, Austria, not involved in the study, said: «
This subgroup analysis shows that the effect of necitumumab was slightly greater in patients with EGFR expressing tumours than it was in the entire SQUIRE population.
Not exact matches
Although the results of the meta - regression
showed no evidence of significant heterogeneity between
subgroups, summary association estimates were slightly different in
subgroup analyses by study design and exposure assessment.
Even though the primary results of a related study investigating the effects of music therapy with children with autism, do not
show that music therapy works better than other therapies,
subgroup analysis identified that children with childhood autism or coexisting intellectual disability improve to a greater extend from music therapy than children with another autism diagnosis.
There were similar results across prespecified
subgroups of patients including
analyses of PD - L1 expression, which
showed hazard ratios in favor of nivolumab.
Additional
analyses favor the hypothesis that MEIS1 exhibits pleiotropy for insomnia and RLS and
show that the observed association with insomnia complaints can not be explained only by the presence of an RLS
subgroup within the cases.
The graphs below
show the results of statistical
analysis of various
subgroups.
The post-hoc
subgroup analyses by sex and baseline triglyceride levels did not
show significant effects.
In the a priori
subgroup analyses, higher fibre intake in the intervention arm than in the control arm
showed a significantly greater reduction in non-HDL cholesterol.
As I've previously written, 9 of the 10
analyses show significant, positive effects for at least some
subgroups of students.
A
subgroup analysis of high risk women who were unmarried and from low SES households (40 %)
showed that home visits reduced the number of subsequent births (mean difference [MD] 0.5, p = 0.02), months that women received welfare (MD 29.9, p = 0.005), reports of behavioural impairment due to substance abuse (incidence 0.41 v 0.73, p = 0.005), records of arrests (incidence 0.16 v 0.90, p < 0.001), convictions (incidence 0.13 v 0.69, p < 0.001), and verified reports of child abuse and neglect involving the mother as perpetrator (incidence 0.11 v 0.53, p < 0.01).
Notes: The study was not powered to
show gender - specific differences; therefore these
subgroup analyses should be interpreted with caution.
Results from the
analyses of the 4 sex / age
subgroups (data not
shown) yielded findings similar to the model based on the full sample.