We tested all possible pairwise comparisons of means by couple drinking categories and gender with a Tukey adjustment for Type 1 error (
Supplementary Figure 1).
NorAQ was developed to measure abuse in the health care system as well as emotional (three items), physical (three items) and sexual (four items) abuse by different perpetrators (see online
supplementary figure S1).
Prevalence rates for the other items on this scale were similar to corresponding items in the NorAQ (see online
supplementary figure S1).
The significant partner presence by attachment avoidance interaction on P2 local peak amplitude, b = 3.29, SE = 1.32, P = 0.013, ƒ2 = 0.371, is presented in the bottom panel of Figure 1 (see also
Supplementary Figure S3).
The meta - analysis of parent - rated child behaviour at long - term follow - up, as shown in online
supplementary figure 4, included child behaviour scores (Strengths and Difficulties Questionnaires (SDQ)-RRB- from three studies.36 53 58 No significant effect was found (d = 0.15; 95 % CI − 0.03 to 0.31).
The meta - analysis on cognitive development included five studies (online
supplementary figure 3).27 46 — 48 55 There was no significant difference between intervention and control groups (d = 0.13; 95 % CI − 0.08 to 0.41).
Participants in two classes of transitory poverty were placed in - between these two extremes in their association with demographic variables (see table 2 and online
supplementary figure 1).
UPDATE 4 November 2009: Another error was found in the corrected
Supplementary figure S8a from December 2008: The previously posted version of the figure had an error due to incorrect application of the procedure described in the paper for updating the network in each century increment.
However,
Supplementary Figure 4 shows that the chosen difference method provides stable estimation of model TCRs provided that the final decade has, like the 1861 — 80 base period, low volcanic forcing.
Moreover, contrary to
Supplementary Figure 4, Supplementary Table 6 gives a median TCR estimate in this case of 1.81 °C, implying an underestimate of 4 %, not 8 %.
The top RH panel of
Supplementary Figure 4 shows that the median TCR estimate when doing so, with 2000 — 09 as the final decade is ~ 2.00 °C.
I had somehow overlooked that the supplementary material included information about the other AR4 models, in
Supplementary Figure 4] However, looking at that figure, it's not particularly clear that most of the AR4 models show a trend toward weakening.
That is what Kosaka and Xie found in their elegant little model experiment — see
their supplementary Figure 3.
As shown in
Supplementary Figure 2 (Figure S2), GSEA analysis revealed that cation channel activity was higher in both cohorts of untreated NSCs and dopaminergic neurons, while it was low in susceptible NSCs treated with amiodarone HCL (Fig.
The acquisition of growth signal self - sufficiency is one of the hallmarks of cancer.28 In this paper, we show that a broad spectrum of spontaneous mutations in one of the endogenous JAK1 alleles is the main mechanism that confers to BaF3 cells cytokine - independent growth capability in vitro and full tumorigenicity in vivo (Online
Supplementary Figure S5), secondary to the upregulation of the JAK1 transcript.
Supplementary figure I shows the forest plots for the age and sex adjusted relative risks.
Similar results were observed using F958C - positive cells (Online
Supplementary Figure S4D).
However, this increase in intrinsic resistance correlated with increased expression of JAK1 protein and RNA levels (Online
Supplementary Figure S4C and D).
Out of the 25 mutants, 6 showed a significant reduction in their sensitivity to INCB018424 (Online
Supplementary Figure S3A).
Supplementary figure J shows the forest plots for stroke and cigarette consumption in men according to age.
Supplementary figure A shows the search terms and flowchart: 13861 abstracts were reviewed (by DM and SB), and any selected for consideration had their reference list manually checked for additional studies.
The 18 reports of women showed that one cigarette per day had 31 % (interquartile range 2 - 46 %) of the excess risk of 20 cigarettes per day (pooled relative risks 1.57 v 2.84), and smoking five cigarettes per day had 43 % (14 - 55 %) the excess risk (relative risk 1.76)(fig 3;
supplementary figure C. (Excluding one study that might have included former smokers in the reference group increased the relative risks for one and 20 cigarettes per day to 1.63 and 2.87.)
Similarly, using a principal component analysis, we also identified suites of molecular functions that are associated with complexity (
Supplementary Figure 11.2).
Cells cultured with CMP6 for two weeks were more resistant to CMP6 than F958V - positive cells which had never been exposed to this inhibitor before (Online
Supplementary Figure S4B).
Supplementary figure M shows examples of individual studies of coronary heart disease or stroke, plotting the observed (reported) relative risks with the ones we estimated using the log - linear model; the fit was generally good.
Altogether, 25 different missense mutations were identified as listed in the Online Supplementary Table S1 and Online
Supplementary Figure S1.
Therefore, proliferation of the F958V - positive cells in the presence of the JAK inhibitor CMP6 is not completely abolished and allows further expansion and proliferation of these cells in the presence of the JAK inhibitor CMP6 for days or even weeks (Online
Supplementary Figure S4A).
We then measured the proliferation of these cells with increasing concentrations of INCB018424 and calculated the IC50 (Online
Supplementary Figure S3B).
Moreover, similarly to autonomous BaF3 harboring spontaneously acquired mutations, all JAK1 mutants induced the constitutive activation of STAT5 and MAP kinase pathways when ectopically expressed in BaF3 cells (Online
Supplementary Figure S2B) for 8 representative mutants.
Compared with WT protein, while KMT2D mutant reduced the level of H3K4me3, this reduction was restored by the HDAC inhibitors romidepsin and chidamide (Figure 3B and Online
Supplementary Figure S2).
As shown in Online
Supplementary Figure S2A, none of these proteins were phosphorylated in BaF3 phe116 or IL -9-selected BaF3 phe116 / 9 in the absence of cytokine.
Importantly, cells expressing the double mutants V658F / F958C showed identical sensitivity to the inhibitor as cells expressing F958C mutant alone (Online
Supplementary Figure S3B).
This gatekeeper Thr residue is not conserved in the JAK kinase family, but the Phe958 residue of JAK1 is the homologous residue of Phe317 in ABL kinase, which is close to the gatekeeper residue and was also found to be mutated in imatinib - resistant BCR - ABL positive patients13, 29,30 (Online
Supplementary Figure S6A and S6B).
We constructed classifiers to distinguish between the baseline and post-intervention states (Supplementary Methods) and achieved prediction accuracies of 96 % for the vacation effect (area under the receiver operating characteristic curve, or AUROC, equal to 0.98) and 85 % for the meditation effect (AUROC = 0.93;
Supplementary Figure S1), supporting the potential for blood - based wellness biomarkers.
However, there is only moderate intersection between the two methods on the genes contributing the most to the predictions (
Supplementary Figure 36c).
The key experiments that will be replicated are those reported in Figure 3B and
Supplementary Figure S6.
Consumption of fermented milk products (soured milk and yogurt) indicated a negative relation with both the oxidative stress and the inflammatory markers (see
supplementary figure C, panel A).
This file contains
Supplementary Figures 1 - 10, Supplementary Tables 1 - 14, a Supplementary Discussion and Supplementary References.
Supplementary Figures 1 - 11, Supplementary Table 1 - 4, Supplementary Methods and Supplementary References
This file contains Supplementary Discussion, Supplementary Methods, Supplementary Notes,
Supplementary Figures S1 - S6 and Supplementary Tables S1 - S9.
This file contains Supplementary Text,
Supplementary Figures 1 - 19, Supplementary Table 1 and Supplementary References.
The file also contains additional references, Supplementary Table 1 and
Supplementary Figures 1 - 4 with legends.
Meta - analysis of the primary outcome is reported in figure 2, and the secondary outcomes are reported in online
supplementary figures.
For the internalising and externalising subscales, no significant difference between intervention and control group was found (see online
supplementary figures 2 and 3).
Not exact matches
We then calculate what the ratio would be if Amazon added 50,000 Amazon workers and 62,500
supplementary workers over a ten year period, as Amazon's RFP projects, and if the city's housing supply grew 20 percent faster than it did in the earlier period.1 We adjusted the 20 percent
figure up or down to reflect differences in metros» level of difficulty in producing new housing, and we assumed that vacancy rates would drop to between 3 and 5 percent of the city's housing stock.
Using
figures from the RFP, we assume the 50,000 new workers would earn $ 100,000 on average, and that
supplementary workers would earn a fraction thereof, as per Amazon's estimates.
It notes that authority to spend money on both missions will come through
supplementary appropriations before Parliament, but given that an election is expected this fall it will likely be a year, or more, before those
figures are tabled.
As in his earlier book, A History of Christian Thought: An Introduction, and its two
supplementary volumes of selections from primary sources, Placher shows himself to be an insightful, judicious and reliable interpreter of the tradition and of significant
figures and issues in contemporary debates.
Dr. Bawumia accused the Finance Minister Seth Terkper of massaging debt to GDP ratio
figures during his presentation of
supplementary budget in July this year.
Since 1999, most of the fiscal budgets of the Nigerian government has followed an increasing dimension in
figures; in 1999: N0.524 trillion, 2000: N0.702 trillion including a
supplementary budget of N0.49 passed in May 2000, 2001: N0.894 trillion, 2002: N0.840 trillion but N1.06 trillion was authorized, 2003: N1.446 trillion, 2004: N1.189 trillion was presented before the Nigerian Parliament, 2005: N1.618 trillion was presented but N1.799 trillion was authorized, 2006: N1.89 trillion, 2007: N2.7 trillion, 2008: N2.45 trillion, 2009: N2.67 trillion, 2010: N4.6 trillion, 2011: N4.972 trillion, 2012: N4.8 trillion, 2013: N4.9 trillion, 2014: N4.6 trillion, 2015: N4.493 trillion excluding a
supplementary budget of N466 billion in November 2015.